Experimental Investigation of Cavitation as a Possible Damage Mechanism in Blast-Induced Traumatic Brain Injury in Post-Mortem Human Subject Heads

2017 ◽  
Vol 34 (8) ◽  
pp. 1589-1602 ◽  
Author(s):  
Robert S. Salzar ◽  
Derrick Treichler ◽  
Andrew Wardlaw ◽  
Greg Weiss ◽  
Jacques Goeller
Keyword(s):  
Traumatic Brain Injury ◽  
Experimental Investigation ◽  
Brain Injury ◽  
Human Subject ◽  
Damage Mechanism ◽  
Post Mortem

Cytokine expression in post-mortem human brain tissue following acute traumatic brain injury

Injury ◽  
2010 ◽  
Vol 41 ◽  
pp. S52-S53
Author(s):  
T. Frugier ◽  
D. O’Reilly ◽  
M.C. Morganti-Kossmann ◽  
C. McLean
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Human Brain ◽  
Brain Tissue ◽  
Cytokine Expression ◽  
Post Mortem ◽  
Human Brain Tissue ◽  
Acute Traumatic Brain Injury

scholarly journals Brain-originated peptides as possible biochemical markers of traumatic brain injury in cerebrospinal fluid post-mortem examination

2018 ◽  
Vol 56 (2) ◽  
pp. 97-103 ◽  
Author(s):  
Mieszko Olczak ◽  
Magdalena Kwiatkowska ◽  
Justyna Niderla-Bielińska ◽  
Dominik Chutorański ◽  
Sylwia Tarka ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Cerebrospinal Fluid ◽  
Brain Injury ◽  
Biochemical Markers ◽  
Post Mortem ◽  
Post Mortem Examination

scholarly journals An update on the rod microglia variant in experimental and clinical brain injury and disease

2021 ◽  
Author(s):  
Katherine R Giordano ◽  
Charlotte R Denman ◽  
Phoebe S Dubisch ◽  
Murtaza Akhter ◽  
Jonathan Lifshitz
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Microscopic Observation ◽  
Cellular Function ◽  
Post Mortem ◽  
General Paresis ◽  
Shaped Cell ◽  
Neuronal Processes ◽  
And Function ◽  
Experimental Traumatic Brain Injury

Abstract Contemporary microglia morphologies include ramified, activated, and amoeboid, with the morphology of microglia considered highly coupled to the cellular function. Rod microglia are an additional activated microglia variant observed in the aging, injured, and diseased brain. Rod microglia were reported frequently in the early 1900’s by neuropathologists in post-mortem cases of general paresis, Alzheimer’s disease, and encephalitis, and then remained largely ignored for almost 100 years. Recent reports have renewed interest in rod microglia, most notably after experimental traumatic brain injury. Rod microglia are formed by the narrowing of the soma and retraction of planar processes, which results in the appearance of an elongated, rod-shaped cell. Rod microglia are most commonly observed in the cortex, aligned perpendicular to the dural surface adjacent to neuronal processes, and the hippocampus, aligned perpendicular to hippocampal layers. Further, rod microglia form trains with one another, apical end to basal end. By replicating the process of sketching microscopic observation, rod microglia are redefined by circumnutation around the long axis. In this update, we summarize the rod microglia variant in clinical and experimental literature and advocate for investigation into mechanisms of rod microglia origin and function.

Post-mortem biochemistry of NSE and S100B: A supplemental tool for detecting a lethal traumatic brain injury?

2018 ◽  
Vol 55 ◽  
pp. 65-73 ◽  
Author(s):  
Monique Sieber ◽  
Jan Dreßler ◽  
Heike Franke ◽  
Dirk Pohlers ◽  
Benjamin Ondruschka
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Post Mortem

Reliability of Post-mortem Biochemical Investigations after Fatal Traumatic Brain Injury

2017 ◽  
Vol 07 (04) ◽  
Author(s):  
Benjamin Ondruschka ◽  
Monique Sieber ◽  
Dirk Pohlers ◽  
Heike Franke ◽  
Jan Drebler
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Post Mortem

Investigation of Cavitation as a Possible Damage Mechanism in Blast-Induced Traumatic Brain Injury

2012 ◽  
Vol 29 (10) ◽  
pp. 1970-1981 ◽  
Author(s):  
Jacques Goeller ◽  
Andrew Wardlaw ◽  
Derrick Treichler ◽  
Joseph O'Bruba ◽  
Greg Weiss
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Damage Mechanism

scholarly journals Neurofibrillary tangle pathology and Braak staging in chronic epilepsy in relation to traumatic brain injury and hippocampal sclerosis: a post-mortem study

Brain ◽  
2011 ◽  
Vol 134 (10) ◽  
pp. 2969-2981 ◽  
Author(s):  
Maria Thom ◽  
Joan Y.W. Liu ◽  
Pam Thompson ◽  
Rahul Phadke ◽  
Marta Narkiewicz ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Hippocampal Sclerosis ◽  
Neurofibrillary Tangle ◽  
Post Mortem ◽  
Chronic Epilepsy ◽  
Braak Staging ◽  
Tangle Pathology

scholarly journals Microcavitation as a Neuronal Damage Mechanism in an In Vitro Model of Blast Traumatic Brain Injury

2017 ◽  
Vol 112 (3) ◽  
pp. 159a ◽  
Author(s):  
Jonathan B. Estrada ◽  
Mark T. Scimone ◽  
Harry C. Cramer ◽  
Lauren Mancia ◽  
Eric Johnsen ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
In Vitro Model ◽  
Neuronal Damage ◽  
Damage Mechanism ◽  
Blast Traumatic Brain Injury ◽  
Vitro Model
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