Early Excision and Late Excision of Heterotopic Ossification after Traumatic Brain Injury Are Equivalent: A Systematic Review of the Literature

2007 ◽  
Vol 24 (11) ◽  
pp. 1675-1686 ◽  
Author(s):  
Byron Chalidis ◽  
Dirk Stengel ◽  
Peter V. Giannoudis
Keyword(s):  
Systematic Review ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Heterotopic Ossification ◽  
Review Of The Literature

scholarly journals Recurrence of heterotopic ossification after removal in patients with traumatic brain injury: A systematic review

2016 ◽  
Vol 59 (4) ◽  
pp. 263-269 ◽  
Author(s):  
Waleed Almangour ◽  
Alexis Schnitzler ◽  
Marjorie Salga ◽  
Charlotte Debaud ◽  
Philippe Denormandie ◽  
...  
Keyword(s):  
Systematic Review ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Heterotopic Ossification

scholarly journals Pterins as Diagnostic Markers of Mechanical and Impact-Induced Trauma: A Systematic Review

2019 ◽  
Vol 8 (9) ◽  
pp. 1383 ◽  
Author(s):  
Angus Lindsay ◽  
Gregory Baxter-Parker ◽  
Steven P. Gieseg
Keyword(s):  
Systematic Review ◽  
Traumatic Brain Injury ◽  
Cardiac Surgery ◽  
Brain Injury ◽  
Liver Resection ◽  
Review Of The Literature ◽  
Multiple Forms ◽  
Concentration Changes ◽  
Exercise Induced

We performed a systematic review of the literature to evaluate pterins as biomarkers of mechanical and impact-induced trauma. MEDLINE and Scopus were searched in March 2019. We included in vivo human studies that measured a pterin in response to mechanical or impact-induced trauma with no underlying prior disease or complication. We included 40 studies with a total of 3829 subjects. Seventy-seven percent of studies measured a significant increase in a pterin, primarily neopterin or total neopterin (neopterin + 7,8-dihydroneopterin). Fifty-one percent of studies measured an increase within 24 h or trauma, while 46% measured increases beyond 48 h. Pterins also showed promise as predictors of post-trauma complications such as sepsis, multi-organ failure and mortality. Exercise-induced trauma and traumatic brain injury caused an immediate increase in neopterin or total neopterin, while patients of multiple trauma had elevated pterin levels that remained above baseline for several days. Pterin concentration changes in response to surgery were variable with patients undergoing cardiac surgery having immediate and sustained pterin increases, while hysterectomy, liver resection or hysterectomy showed no change. This review provides systematic evidence that pterins, in particular neopterin and total neopterin, increase in response to multiple forms of mechanical or impact-induced trauma.

Pediatric Mild Traumatic Brain Injury: Who Can Be Managed at a Non-pediatric Trauma Center Hospital? A Systematic Review of the Literature

2021 ◽  
pp. 000313482110508
Author(s):  
Olivia A. Keane ◽  
Mauricio A. Escobar ◽  
Lucas P. Neff ◽  
Ian C. Mitchell ◽  
Joshua J. Chern ◽  
...  
Keyword(s):  
Systematic Review ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Trauma Center ◽  
Pediatric Trauma ◽  
Evidence Based ◽  
Review Of The Literature ◽  
Mild Tbi ◽  
Pediatric Tbi ◽  
Pediatric Trauma Center

Background Pediatric traumatic brain injury (TBI) affects about 475,000 children in the United States annually. Studies from the 1990s showed worse mortality in pediatric TBI patients not transferred to a pediatric trauma center (PTC), but did not examine mild pediatric TBI. Evidence-based guidelines used to identify children with clinically insignificant TBI who do not require head CT were developed by the Pediatric Emergency Care Applied Research Network (PECARN). However, which patients can be safely observed at a non-PTC is not directly addressed. Methods A systematic review of the literature was conducted, focusing on management of pediatric TBI and transfer decisions from 1990 to 2020. Results Pediatric TBI patients make up a great majority of preventable transfers and admissions, and comprise a significant portion of avoidable costs to the health care system. Majority of mild TBI patients admitted to a PTC following transfer do not require ICU care, surgical intervention, or additional imaging. Studies have shown that as high as 83% of mild pediatric TBI patients are discharged within 24 hrs. Conclusions An evidence-based clinical practice algorithm was derived through synthesis of the data reviewed to guide transfer decision. The papers discussed in our systematic review largely concluded that transfer and admission was unnecessary and costly in pediatric patients with mild TBI who met the following criteria: blunt, no concern for NAT, low risk on PECARN assessment, or intermediate risk on PECARN with negative imaging or imaging with either isolated, nondisplaced skull fractures without ICH and/or EDH, or SDH <0.3 cm with no midline shift.

Sleep-Wake Disturbances and Fatigue after Pediatric Traumatic Brain Injury: A Systematic Review of the Literature

2015 ◽  
Vol 32 (20) ◽  
pp. 1539-1552 ◽  
Author(s):  
Charlotte Gagner ◽  
Catherine Landry-Roy ◽  
France Lainé ◽  
Miriam H. Beauchamp
Keyword(s):  
Systematic Review ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Review Of The Literature ◽  
Pediatric Traumatic Brain Injury
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