Sex and Region-Specific Associations of Bone Mineral Content, Muscle Mass, and Fat Mass with Insulin Resistance

2020 ◽  
Vol 18 (10) ◽  
pp. 471-478
Author(s):  
Kayoung Lee
Keyword(s):  
Insulin Resistance ◽  
Bone Mineral Content ◽  
Muscle Mass ◽  
Bone Mineral ◽  
Fat Mass ◽  
Mineral Content

P1569ADIPONECTIN IS ASSOCIATED WITH DECLINE IS SKELETAL MUSCLE MASS AND BONE MINERAL CONTENT IN PATIENTS ON HEMODIALYSIS

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Hiroshi Ogawa ◽  
Toshimitsu Koga ◽  
Daisuke Fuwa ◽  
Hirofumi Tamaki ◽  
Takayuki Nanbu ◽  
...  
Keyword(s):  
Skeletal Muscle ◽  
Bone Mineral Content ◽  
Muscle Mass ◽  
Body Fat ◽  
Bone Mineral ◽  
Fat Mass ◽  
Skeletal Muscle Mass ◽  
Mineral Content ◽  
Body Fat Mass ◽  
Total Plasma

Abstract Background and Aims Patients on hemodialysis are prone to undernutrition, malnutrition-inflammation-atherosclerosis (MIA) syndrome, and protein-energy wasting (PEW). One of the major adipocytokines adiponectin (ADPN) is involved in anti-arteriosclerotic and anti-inflammatory processes. However, ADPN is implicated in muscle weakness and loss of muscle mass in the elderly in addition to sarcopenia. At the 2019 ERA-EDTA Congress, we announced that total plasma ADPN levels in patients on hemodialysis (HD) showed a significant inverse correlation with BMI, body fat in percentage, mass and estimated skeletal muscle mass, and ADPN may be involved in sarcopenia in patients on HD. Herein, we investigated the association of ADPN level with sarcopenia in patients on HD using a method different from the one used in our previous study. We examined the relationship between total plasma ADPN level and the rate of change in estimated skeletal muscle mass, bone mineral content, and body fat mass over 5 years after the plasma ADPN measurement. Furthermore, we analyzed whether an elevated ADPN level was predictive of a subsequent decline in these parameters. Method Total plasma ADPN levels were measured using ELISA (Bio Vendor-Laboratorni Medicina a.s., Czech Republic) in 42 male patients on HD (age: 51.1 ± 9.0 years, dialysis vintage: 144.8 ± 99.2 months, BMI: 21.8 ± 3.2, dry BW: 62.0 ± 10.9 kg, dialysis time: 15.6 ± 3.1 hours/week). The estimates of skeletal muscle mass, bone mineral content, and body fat mass were made using multi-frequency bioelectrical impedance analysis (MFBIA) within the same year when total plasma ADPN level were first measured in 2011 as well as in 2016. We then calculated the rates of change in the estimated skeletal muscle mass, bone mineral content, and body fat mass over the 5 years and correlated these parameters with the total plasma ADPN measurements. Results Conclusion Total plasma ADPN levels inversely correlate with larger rates of decrease in estimated skeletal muscle mass and bone mineral content in patients on HD. This suggests that ADPN may play a role in the decline in skeletal muscle mass and bone mineral content over time in patients on HD.

scholarly journals Maternal high fat feeding results in higher fat mass and bone mineral content in weanling but not 3 month old female offspring

2013 ◽  
Vol 27 (S1) ◽  
Author(s):  
Laura M Castelli ◽  
Paula M Miotto ◽  
Rebecca EK MacPherson ◽  
Bryan D Johnston ◽  
Paul J LeBlanc ◽  
...  
Keyword(s):  
Bone Mineral Content ◽  
Bone Mineral ◽  
Fat Mass ◽  
Mineral Content ◽  
Female Offspring ◽  
High Fat ◽  
Fat Feeding

scholarly journals Lean Mass is a Stronger Predictor of Bone Mineral Content and Density than Fat Mass and Physical Activity in Young and Old Women

2007 ◽  
Vol 39 (Supplement) ◽  
pp. S439
Author(s):  
Gunnhildur Hinriksdóttir ◽  
Sigurbjörn Á. Arngrímsson ◽  
Mark M. Misic ◽  
Daina M. Mallard ◽  
Ellen M. Evans
Keyword(s):  
Physical Activity ◽  
Bone Mineral Content ◽  
Bone Mineral ◽  
Fat Mass ◽  
Lean Mass ◽  
Mineral Content

Fat mass is negatively associated with bone mineral content in Koreans

2011 ◽  
Vol 23 (7) ◽  
pp. 2009-2016 ◽  
Author(s):  
J. H. Kim ◽  
H. J. Choi ◽  
M. J. Kim ◽  
C. S. Shin ◽  
N. H. Cho
Keyword(s):  
Bone Mineral Content ◽  
Bone Mineral ◽  
Fat Mass ◽  
Mineral Content ◽  
Negatively Associated

scholarly journals Association of Lean Tissue and Fat Mass with Bone Mineral Content in Children and Adolescents

2002 ◽  
Vol 10 (1) ◽  
pp. 56-60 ◽  
Author(s):  
Angelo Pietrobelli ◽  
Myles S. Faith ◽  
Jack Wang ◽  
Paolo Brambilla ◽  
Giuseppe Chiumello ◽  
...  
Keyword(s):  
Bone Mineral Content ◽  
Children And Adolescents ◽  
Bone Mineral ◽  
Fat Mass ◽  
Mineral Content ◽  
Lean Tissue

scholarly journals Diabetes during Pregnancy Does Not Alter Whole Body Bone Mineral Content in Infants

1997 ◽  
Vol 82 (12) ◽  
pp. 3993-3997 ◽  
Author(s):  
Alexandre Lapillonne ◽  
Sophie Guerin ◽  
Pierre Braillon ◽  
Olivier Claris ◽  
Pierre D. Delmas ◽  
...  
Keyword(s):  
Birth Weight ◽  
Bone Mineral Content ◽  
Bone Mineral ◽  
Fat Mass ◽  
Gestational Age ◽  
Mineral Content ◽  
Whole Body ◽  
X Ray ◽  
Diabetic Mothers ◽  
Body Bone

A previous study using single photon absorptiometry has reported low bone mineral density of the radius in infants of diabetic mothers. The aim of this study was to assess by dual x-ray absorptiometry the whole body bone mineral content (WbBMC) and the body composition of 40 infants of diabetic mothers at birth (mean gestational age ± sd, 37.5 ± 1.3 weeks; mean birth weight ± sd, 3815 ± 641 g). WbBMC was not correlated with gestational age, but was well correlated with birth weight (r = 0.73; P = 0.0001) and also with fat mass (r = 0.87; P = 0.0001) and lean mass (r = 0.42; P = 0.008). The z-scores ± sd adjusted for weight for WbBMC and fat mass were significantly increased (1.3 ± 0.9 and 2.6 ± 1.3, respectively (P < 0.0001), but were not significantly influenced either by in utero growth or by the type of the diabetes mellitus of the mother. Bone mineralization and fat mass studied by whole body dual x-ray absorptiometry are increased at birth in these infants compared with reference curves.

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