Associations of Serum Uric Acid with Endogenous Cholesterol Synthesis Indices in Men with High Cardiometabolic Risk

2020 ◽  
Vol 18 (4) ◽  
pp. 212-218
Author(s):  
Marek Vecka ◽  
Aleš Žák ◽  
Eva Tvrzická ◽  
Magdalena Dušejovská ◽  
Barbora Staňková ◽  
...  
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Cholesterol Synthesis ◽  
Cardiometabolic Risk ◽  
Endogenous Cholesterol

scholarly journals Relation between uric acid and metabolic syndrome in subjects with cardiometabolic risk

2015 ◽  
Vol 13 (2) ◽  
pp. 202-208 ◽  
Author(s):  
Hellen Abreu da Silva ◽  
Júlia Cristina Cardoso Carraro ◽  
Josefina Bressan ◽  
Helen Hermana Miranda Hermsdorff
Keyword(s):  
Metabolic Syndrome ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Abdominal Obesity ◽  
Health Program ◽  
Cardiovascular Health ◽  
Cardiometabolic Risk ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Potential Biomarker

Objective To identify possible relations between serum uric acid levels and metabolic syndrome and its components in a population with cardiometabolic risk. Methods This cross-sectional study included 80 subjects (46 women), with mean age of 48±16 years, seen at the Cardiovascular Health Program. Results The prevalence of hyperuricemia and metabolic syndrome was 6.3% and 47.1%, respectively. Uric acid level was significantly higher in individuals with metabolic syndrome (5.1±1.6mg/dL), as compared to those with no syndrome or with pre-syndrome (3.9±1.2 and 4.1±1.3mg/dL, respectively; p<0.05). The uric acid levels were significantly higher in men presenting abdominal obesity, and among women with abdominal obesity, lower HDL-c levels and higher blood pressure (p<0.05). Conclusion Uric acid concentrations were positively related to the occurrence of metabolic syndrome and its components, and there were differences between genders. Our results indicate serum uric acid as a potential biomarker for patients with cardiometabolic risk.

scholarly journals The Relationship Between Serum Uric Acid and Cardiometabolic Risk Factors in Iranian Children and Adolescents

2021 ◽  
Vol 9 (2) ◽  
pp. 167-174
Author(s):  
Motahar Heidari-Beni ◽  
◽  
Roya Riahi ◽  
Fatemeh Mohebpour ◽  
Majid Khademian ◽  
...  
Keyword(s):  
Risk Factors ◽  
Uric Acid ◽  
Waist Circumference ◽  
Children And Adolescents ◽  
Serum Uric Acid ◽  
Cardiometabolic Risk ◽  
Population Based ◽  
Cardiometabolic Risk Factors ◽  
Potential Association ◽  
Iranian Children

Context: There has been an increasing interest in epidemiological and clinical studies concerning the role of uric acid in cardiometabolic diseases, especially in children and adolescents. However, these potential relationships remain undiscovered; accordingly, its pathophysiological mechanisms remain unrecognized. This study aimed to assess the potential association between Serum Uric Acid (SUA) levels and cardiometabolic risk factors in a population-based sample of Iranian children and adolescents. Objectives: This study aimed to assess the potential association between Serum Uric Acid (SUA) levels and cardiometabolic risk factors in a population-based sample of Iranian children and adolescents. Methods: The data of 595 individuals aged 7-18 years were assessed in this research. Anthropometric measurements and laboratory tests were performed according to standardized protocols. Results: The Mean±SD age of the 595 explored students was 12.39±3.07 years. The overall Mean±SD SUA level of the study participants was measured as 4.22±1.13 mg/dL, with significant gender-wise differences (4.04±0.97 mg/dL vs 4.38±1.24 mg/dL, respectively; P<0.05). The prevalence of hyperuricemia based on the 90th percentile of SUA levels was equal to 10.6%. There was a positive association between SUA levels and abdominal obesity (waist circumference: ≥90th percentile) [Odds Ratio (OR): 1.54; 95% Confidence Interval (CI): 1.26 to 1.86] and general obesity [gender-specific Body Mass Index (BMI) for >95th percentile] (OR: 2.32; 95% CI: 1.74 to 3.11). Conclusions: This study suggested BMI and waist circumference as cardiometabolic risk factors, i.e. significantly associated with SUA levels in children and adolescents.

scholarly journals Serum Uric Acid Levels are Associated with Cardiometabolic Risk Factors in Healthy Young and Middle-Aged Adults

2018 ◽  
Author(s):  
Thaís da Silva Ferreira ◽  
Julia Freitas Rodrigues Fernandes ◽  
Luciene da Silva Araújo ◽  
Lívia de Paula Nogueira ◽  
Priscila Mansur Leal ◽  
...  
Keyword(s):  
Risk Factors ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Cardiometabolic Risk ◽  
Cardiometabolic Risk Factors ◽  
Middle Aged ◽  
Middle Aged Adults

scholarly journals Serum Uric Acid Levels and Cardiometabolic Risk Among Adolescents

2019 ◽  
Vol 51 (Supplement) ◽  
pp. 409
Author(s):  
Josi R. Gabaldon ◽  
Nate T. Berry ◽  
Jessica Dollar ◽  
Lilly Shanahan ◽  
Susan Keane ◽  
...  
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Cardiometabolic Risk

scholarly journals Association Between Serum Uric Acid Levels and Cardiometabolic Risk Factors Among Japanese Junior High School Students

2010 ◽  
Vol 74 (8) ◽  
pp. 1570-1577 ◽  
Author(s):  
Minoru Hongo ◽  
Hiroya Hidaka ◽  
Shigeko Sakaguchi ◽  
Keisuke Nakanishi ◽  
Motoki Ichikawa ◽  
...  
Keyword(s):  
Risk Factors ◽  
High School ◽  
Uric Acid ◽  
High School Students ◽  
Serum Uric Acid ◽  
Junior High School ◽  
Cardiometabolic Risk ◽  
Junior High School Students ◽  
Cardiometabolic Risk Factors ◽  
School Students

scholarly journals Soft Drink Raises Plasma Uric Acid in Comparison to Fruit: Results from a Four-Week, Randomized Controlled Trial

2017 ◽  
Author(s):  
Simonette R. Mallard ◽  
Lisa Te Morenga
Keyword(s):  
Risk Factors ◽  
Uric Acid ◽  
Serum Uric Acid ◽  
Cardiometabolic Risk ◽  
Soft Drink ◽  
Controlled Trial ◽  
Elevated Serum ◽  
Cardiometabolic Risk Factors ◽  
Increased Risk ◽  
Dried Fruit

High fructose and sugar-sweetened soft drink (SSSD) intakes are associated with elevated blood uric acid concentrations and increased risk of gout and cardiovascular disease. Fruits are naturally high in fructose but their effect on cardiometabolic risk is unknown. We examined the effect on serum uric acid and cardiometabolic risk factors of consuming fructose from either fruit or SSSD in overweight adults. 48 healthy, overweight (BMI&ge; 28 kg/m2) men (n=21) and women (n=20) were randomised to either a fruit (n = 19) or SSSSD (n = 22) intervention for 4 weeks. The fruit group received 6 items of fresh and dried fruit per day and the SSSD group received 955ml of SSSD per day with treatments matched for energy and fructose content. Serum uric acid concentrations were significantly reduced in men in the fruit group compared to the SSSD group (difference 57.2 &mu;mol/L [95% CI: 16.4, 98.0], p= 0.008) but there was no difference amongst women (1.3 &mu;mol/L [95%CI: -9.5, 6.9], p= 0.295). There differences in weight change or other cardiometabolic risk factors. These findings suggest no need to restrict fruit intake in individuals with elevated serum uric acid concentrations, such as those with gout.

Serum Uric Acid and Impaired Glucose Tolerance: The Cardiometabolic Risk in Chinese (CRC) Study

2015 ◽  
Vol 73 (1) ◽  
pp. 155-162 ◽  
Author(s):  
Qinqin Qiu ◽  
Ying Gong ◽  
Xuekui Liu ◽  
Lianjun Dou ◽  
Yu Wang ◽  
...  
Keyword(s):  
Uric Acid ◽  
Glucose Tolerance ◽  
Impaired Glucose Tolerance ◽  
Serum Uric Acid ◽  
Cardiometabolic Risk
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