The Effect of Body Mass Index on Fasting Blood Glucose and Development of Diabetes Mellitus After Initiation of Extended-Release Niacin

2010 ◽  
Vol 8 (1) ◽  
pp. 79-84 ◽  
Author(s):  
Ardelle Libby ◽  
Joy Meier ◽  
Julio Lopez ◽  
Arthur L.M. Swislocki ◽  
David Siegel
Keyword(s):  
Diabetes Mellitus ◽  
Body Mass Index ◽  
Blood Glucose ◽  
Body Mass ◽  
Extended Release ◽  
Fasting Blood Glucose

Can Response to Bedtime Insulin with Daytime Sulfonylurea Be Predicted in Patients with Type 2 Diabetes Mellitus?

1997 ◽  
Vol 13 (5) ◽  
pp. 200-205
Author(s):  
Julie C Oki ◽  
Alexander Tal ◽  
Leland Graves ◽  
William L Isley
Keyword(s):  
Diabetes Mellitus ◽  
Body Mass Index ◽  
Blood Glucose ◽  
Body Mass ◽  
Age Of Onset ◽  
Blood Glucose Concentration ◽  
Fasting Blood Glucose ◽  
Type 2 Dm ◽  
Hb Concentration

Objective: To determine characteristics predictive of response in patients with Type 2 diabetes mellitus (Type 2 DM) who demonstrate good or poor blood glucose control while receiving bedtime insulin with daytime sulfonylurea (BIDS) therapy. Methods: A retrospective chart review of patients with Type 2 DM receiving BIDS therapy was performed. The criterion for responders was the mean of two consecutively obtained glycosylated hemoglobin (Hb) concentrations being less than or equal to 10.2% (HbA1c ≤7.0%). Setting: A university-affiliated diabetes specialty clinic staffed consistently by a pharmacist diabetes educator, four endocrinologists, and a pharmacotherapy specialist. Patients: Thirty-one patients with Type 2 DM who were predominantly African-American and women who had documented regular follow-up examinations for more than 12 months while receiving BIDS therapy. Data Collection and Measurements: Gender, ethnicity, height, weight, calculated body mass index, age of onset of diabetes mellitus, duration of diabetes mellitus before BIDS therapy, pre-BIDS treatment regimen, dosages of NPH insulin and glyburide, glycosylated Hb concentration, fasting blood glucose concentration, and duration of BIDS therapy were recorded. Results: There were no differences in age of onset of diabetes mellitus, duration of diabetes mellitus before BIDS was initiated, duration of therapy with BIDS, or baseline glycosylated Hb concentration between responders (n = 15) and nonresponders (n = 16). Patients in the responder group weighed less, had a lower body mass index, required smaller dosages of both glyburide and NPH insulin, and achieved a lower fasting blood glucose concentration. Conclusions: In this study population, with the exception of body mass index, there was no difference in suggested clinical characteristics of response between responders and nonresponders.

scholarly journals Relationship between fasting blood glucose and body mass index among students of a medical college

2019 ◽  
pp. 23
Author(s):  
Saritha Susan Vargese ◽  
T.M. Joseph ◽  
E. Mathew
Keyword(s):  
Body Mass Index ◽  
Blood Glucose ◽  
Body Mass ◽  
Teaching Hospital ◽  
Tertiary Care ◽  
Fasting Blood Glucose ◽  
Tertiary Care Teaching Hospital ◽  
Care Teaching ◽  
Increased Risk ◽  
Study Participants

Background: Obesity is one of the most important modifiable risk factors in the pathogenesis of lifestyle diseases like atherosclerosis, hypertension and type 2 diabetes mellitus. Overweight or obese adolescents are at an increased risk of developing diabetes and hypertension in future. A study was done to determine the relationship between body mass index and fasting blood glucose among students of a tertiary care teaching hospital. Materials and methods: A cross sectional analytical study was carried out among all medical students in a tertiary care teaching hospital in Kerala who consented to participate after obtaining approval from Institutional Research and Ethics Committee. The study tools used were standardized weighing machine, stadiometer, Accu-check glucometer and strips, disposable needles and pre-designed questionnaire. Results: Among the 254 study participants, 67% were females. The prevalence of impaired fasting glucose is 18.11% in the study population. No significant correlation was found between fasting blood glucose and body mass index. There was an increase in median FBS as the BMI increases, though not statistically significant (p=0.08). In the linear regression model, the statistic R2 explains that 7.9% of the variability in fasting blood glucose is explained by body mass index. Conclusion: The prevalence of prediabetes among the study participants was very high and it was higher among those who were overweight. The need of the hour is to identify the high-risk group in the community right from the young age and initiate trials or intervention studies to prevent or delay the onset of diabetes.

scholarly journals Body Mass Index, Waist Circumference, Body Fat, Fasting Blood Glucose in a Sample of Moroccan Adolescents Aged 11–17 Years

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Slimane Mehdad ◽  
Abdeslam Hamrani ◽  
Khalid El Kari ◽  
Asmaa El Hamdouchi ◽  
Amina Barakat ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Blood Glucose ◽  
Waist Circumference ◽  
Body Mass ◽  
Body Fat ◽  
Significant Relationship ◽  
Weight Status ◽  
Fasting Blood Glucose ◽  
Normal Weight ◽  
Screening Tools

Objectives. The study aimed to assess the relationship between body fat and each of body mass index (BMI) and waist circumference (WC), and to test the effectiveness of fat mass (FM), percent of body fat (PBF), BMI, and WC in predicting high levels of fasting blood glucose (FBG).Methods. A total of 167 adolescents aged 11–17 years were recruited from Rabat region. BMI and WC were determined using standard equipments. FM and PBF were derived from isotope dilution technique. FBG was determined by the hexokinase method.Results. Regardless of the weight status, BMI showed a strong positive correlation with FM and PBF in both genders. WC was significantly correlated with FM in boys and girls, and with PBF in different groups of girls and boys of the study sample. However, there was no significant relationship between WC and PBF in normal weight and overweight-obese groups of boys. FBG was highly correlated with FM and PBF in girls of the study sample and in overweight-obese girls. Similar significant relationship between FBG and both BMI and WC was observed in overweight-obese girls, while there was no significant association between FBG and other variables in boys and normal-weight girls.Conclusion. BMI and WC were closely associated with FM and PBF, respectively. However, the degree of these associations depends on gender and weight status. BMI may provide a better proxy estimate of overall adiposity than WC; nevertheless, both of them would appear to be a reasonable surrogate for FM and PBF as screening tools to identify adolescents at risk of developing excess body fat and high level of FBG.

scholarly journals GAMBARAN KADAR GLUKOSA DARAH PUASA MAHASISWA FAKULTAS KEDOKTERAN UNIVERSITAS SAM RATULANGI ANGKATAN 2011 DENGAN INDEKS MASSA TUBUH ≥ 23 kg/m2

2013 ◽  
Vol 1 (1) ◽  
Author(s):  
Gracia Rorong ◽  
Stefana Kaligis ◽  
Diana Purwanto
Keyword(s):  
Body Mass Index ◽  
Body Weight ◽  
Blood Glucose ◽  
Blood Glucose Level ◽  
Body Mass ◽  
Glucose Level ◽  
Fasting Blood Glucose ◽  
Fasting Blood Glucose Level ◽  
Cross Sectional ◽  
Purposive Sampling

Abstract: Glucose is a main compound that has important role in preparation and development  of energy in human body. Blood glucose level is the amount of glucose in the blood. One of the factors that affects blood glucose level is body weight. Body weight is affected by several factors, such as aged, gender, and physical activities. Overweight may cause insulin resistance, results in increasing of the blood glucose level. This study aimed to describe the fasting blood glucose level at students Faculty of Medicine year 2011 Sam Ratulangi University with Body Mass Index (BMI) ≥23 kg/m2. Research method used for this study was cross sectional descriptive survey with purposive sampling method. From 26 respondents, 12 overweight (BMI ≥23 kg/m2) respondents (46,15%) had average fasting blood glucose level 85,4 mg/dL and 14 obese (BMI ≥25 kg/m2) respondents (53,85%) had average fasting blood glucose level 86 mg/dL. Conclusion: the description of fasting blood glucose level at students Faculty of Medicine year 2011 Sam Ratulangi University with Body Mass Index (BMI) ≥23 kg/m2 is at normal level (80-100 mg/dL). Keywords: BMI ≥23 kg/m2, Fasting blood glucose, students year 2011     Abstrak: Glukosa merupakan suatu molekul utama yang berperan penting dalam penyediaan dan pembentukan energi di dalam tubuh. Kadar glukosa darah adalah jumlah kandungan glukosa dalam darah. Salah satu faktor yang mempengaruhi kadar glukosa darah adalah berat badan. Berat badan dipengaruhi oleh beberapa faktor, antara lain usia, jenis kelamin, dan aktivitas fisik. Kelebihan berat badan dapat menyebabkan resistensi insulin sehingga kadar glukosa dalam darah meningkat. Peningkatan kadar glukosa darah merupakan salah satu penanda sindroma metabolik. Penelitian ini bertujuan untuk mengetahui gambaran kadar glukosa darah puasa pada mahasiswa Fakultas Kedokteran Universitas Sam Ratulangi Angkatan 2011 dengan Indeks Massa Tubuh (IMT) ≥23 kg/m2. Jenis penelitian berupa penelitian survey deskriptif cross sectional dengan metode purposive sampling. Sampel penelitian sebanyak 26 orang responden. Hasil penelitian ini didapatkan 12 orang responden (46,15%) yang overweight (IMT ≥23 kg/m2) memiliki rata-rata kadar glukosa darah puasa 85,4 mg/dL dan 14 orang responden (53,85%) yang obesitas (IMT ≥25 kg/m2) memilki rata-rata kadar glukosa darah puasa 86 mg/dL. Simpulan: semua responden mahasiswa Fakultas Kedokteran Universitas Sam Ratulangi Angkatan 2011 memiliki kadar glukosa darah puasa normal (80-100 mg/dL). Kata Kunci: Glukosa darah puasa, IMT ≥23 kg/m2, mahasiswa angkatan 2011

scholarly journals The Relationship Between Body Mass Index and Incident Diabetes Mellitus in Chinese Aged Population: A Cohort Study

2021 ◽  
Author(s):  
Molian Tang ◽  
Yiquan Zhou ◽  
Jialu Wang ◽  
Yanping Wan ◽  
Renying Xu
Keyword(s):  
Diabetes Mellitus ◽  
Body Mass Index ◽  
Cohort Study ◽  
High Risk ◽  
Body Mass ◽  
Fasting Blood Glucose ◽  
Cox Proportional Hazards ◽  
Incident Diabetes ◽  
Chinese Elderly ◽  
Aged Population

Abstract BackgroundPrevious studies reported that aged population with overweight had a lower mortality after cardiovascular diseases attack, indicating being thinner might not be better. However, the debate is ongoing what is optimal range of body mass index (BMI) for aged population. We aimed to evaluate the association between BMI and incident diabetes mellitus (DM) in Chinese elderly people.Methods6,489 Chinese elderly people (3,828 men and 2,661 women) with medium age of 69 years (interquartile range: 67-74 years) were included in this cohort study. BMI was measured at baseline (2014). All the participants were further classified into eight groups based on baseline BMI with 2.0 kg/m2 interval: ≤17.9 kg/m2, 18.0-19.9 kg/m2, 20.0-21.9 kg/m2, 22.0-23.9 kg/m2, 24.0-25.9 kg/m2, 26.0-27.9 kg/m2, 28.0-29.9 kg/m2, and ≥30.0 kg/m2. Fasting blood glucose (FBG) and glycated hemoglobin A1c (HbA1c) were annually measured during follow-up (2014-2019). DM was confirmed if either FBG ≥7.0 mmol/L or HbA1c ≥6.5%. We used the Cox proportional hazards regression model to evaluate the association between BMI and incident DM.ResultsComparing individuals with a BMI range of 20.0~21.9 kg/m2 (reference), the hazards ratio for incident DM was 2.07 (95% CI: 1.33, 3.22), 2.07 (95% CI: 1.33, 3.23), 2.18 (95% CI: 1.37, 3.47), 2.68 (95% CI: 1.61, 4.46), and 2.26 (95% CI: 1.17, 4.37) for the group with a BMI range of 22.0-23.9 kg/m2, 24.0-25.9 kg/m2, 26.0-27.9 kg/m2, 28.0-29.9 kg/m2, and ≥30.0 kg/m2 after adjusting baseline age, sex, blood pressure, lipid profiles, and eGFR. Each unit increase of BMI (=1.0 kg/m2) was associated with a high risk of 9% (HR=1.09, 95% CI: 1.05, 1.14, P for trend<0.001) after adjusting for above-mentioned confounders.ConclusionsHigh BMI was associated with high risk of developing DM in Chinese aged population. To lower the incidence of DM, it is better to be thinner than heavier.

scholarly journals The Relationship between Body Mass Index and Incident Diabetes Mellitus in Chinese Aged Population: A Cohort Study

2021 ◽  
Vol 2021 ◽  
pp. 1-8
Author(s):  
M. L. Tang ◽  
Y. Q. Zhou ◽  
A. Q. Song ◽  
J. L. Wang ◽  
Y. P. Wan ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Body Mass Index ◽  
Cohort Study ◽  
Body Mass ◽  
Fasting Blood Glucose ◽  
Incident Diabetes ◽  
Chinese Elderly ◽  
Aged Population ◽  
Cox Proportional Hazard ◽  
Cox Proportional Hazard Regression

Objectives. Previous studies reported that overweight older adults had a lower mortality after cardiovascular diseases attack, indicating being thinner might not always be better. However, there is an ongoing debate about what is the optimal range of body mass index (BMI) for the aged population. We aimed to evaluate the value of BMI for the prediction of incident diabetes mellitus (DM) in the Chinese elderly population. Methods. A total number of 6,911 Chinese elderly people (4,110 men and 2,801 women, aged 71 ± 6.0 years) were included in this cohort study. BMI was measured at baseline (Jan 1, 2014, to Dec 31, 2014). All the participants were further classified into six groups: <18.5 kg/m2, 18.5 to <22.5 kg/m2, 22.5 to <25.0 kg/m2, 25.0 to <27.5 kg/m2, 27.5 to <30.0 kg/m2, and ≥30.0 kg/m2. Fasting blood glucose (FBG) and glycated hemoglobin A1c (HbA1c) were annually measured during follow-up (Jan 1, 2015-May 31, 2019). DM was confirmed if either FBG ≥ 7.0   mmol / L or HbA 1 c ≥ 6.5 % . We used the Cox proportional hazard regression model to evaluate the association between BMI and the prediction of incident DM. Results. Comparing individuals with a BMI range of 18.5 to <22.5 kg/m2 (reference), the hazard ratio for incident DM was 2.13 (95% CI: 1.54~2.95), 2.14 (95% CI: 1.53~3.00), 3.17 (95% CI: 2.19~4.59), 3.15 (95% CI: 1.94~5.09), and 3.14 (95% CI: 1.94~5.09) for the group with a BMI range of 22.5 to <25.0 kg/m2, 25.0 to <27.5 kg/m2, 27.5 to <30.0 kg/m2, and ≥30.0 kg/m2 after adjusting for baseline age, sex, blood pressure, lipid profiles, and eGFR ( P trend < 0.001), after adjusting for the abovementioned confounders. The association tended to be closer in men and young participants, compared with their counterparts. Conclusions. High BMI was associated with a high risk of developing DM in the Chinese aged population. Thus, it is optimal for the aged population to maintain their body weight within a reasonable range to prevent chronic diseases.

scholarly journals Temporal Association of Changes in Fasting Blood Glucose and Body Mass Index With Diagnosis of Pancreatic Cancer

2009 ◽  
Vol 104 (9) ◽  
pp. 2318-2325 ◽  
Author(s):  
Rahul Pannala ◽  
Cynthia L Leibson ◽  
Kari G Rabe ◽  
Lawrence J Timmons ◽  
Jeanine Ransom ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Body Mass Index ◽  
Blood Glucose ◽  
Body Mass ◽  
Fasting Blood Glucose ◽  
Temporal Association
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