Cardiorespiratory Fitness and Visceral Fat Impact the Relationship between Psychological Fitness and Metabolic Syndrome in Japanese Males with Type 2 Diabetes Mellitus

2004 ◽  
Vol 2 (3) ◽  
pp. 172-179 ◽  
Author(s):  
M. Nagano ◽  
H. Sasaki ◽  
S. Kumagai
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Type 2 Diabetes Mellitus ◽  
Cardiorespiratory Fitness ◽  
Visceral Fat ◽  
The Relationship

Relative Associations of Fitness and Visceral Fat to Metabolic Syndrome in Type 2 Diabetes Mellitus

2004 ◽  
Vol 36 (Supplement) ◽  
pp. S84???S85
Author(s):  
Yuko Kai ◽  
Buhao Zou ◽  
Mayumi Nagano ◽  
Haruka Sasaki ◽  
Shuzo Kumagai
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Type 2 Diabetes Mellitus ◽  
Visceral Fat

Relative Associations of Fitness and Visceral Fat to Metabolic Syndrome in Type 2 Diabetes Mellitus

2004 ◽  
Vol 36 (Supplement) ◽  
pp. S84-S85 ◽  
Author(s):  
Yuko Kai ◽  
Buhao Zou ◽  
Mayumi Nagano ◽  
Haruka Sasaki ◽  
Shuzo Kumagai
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Type 2 Diabetes Mellitus ◽  
Visceral Fat

scholarly journals Metabolic syndrome and myocardium steatosis in subclinical type 2 diabetes mellitus: a 1H-magnetic resonance spectroscopy study

2020 ◽  
Vol 19 (1) ◽  
Author(s):  
Yue Gao ◽  
Yan Ren ◽  
Ying-kun Guo ◽  
Xi Liu ◽  
Lin-jun Xie ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Metabolic Syndrome ◽  
Type 2 Diabetes Mellitus ◽  
Magnetic Resonance ◽  
Myocardial Dysfunction ◽  
Myocardial Deformation ◽  
Myocardial Steatosis ◽  
The Relationship

Abstract Background Metabolic syndrome (MetS) is a cluster of metabolic abnormalities that collectively cause an increased risk of type 2 diabetes mellitus (T2DM) and nonatherosclerotic cardiovascular disease. This study aimed to evaluate the role of myocardial steatosis in T2DM patients with or without MetS, as well as the relationship between subclinical left ventricular (LV) myocardial dysfunction and myocardial steatosis. Methods and materials We recruited 53 T2DM patients and 20 healthy controls underwent cardiac magnetic resonance examination. All T2DM patients were subdivide into two group: MetS group and non-MetS. LV deformation, perfusion parameters and myocardial triglyceride (TG) content were measured and compared among these three groups. Pearson’s and Spearman analysis were performed to investigate the correlation between LV cardiac parameters and myocardial steatosis. The receiver operating characteristic curve (ROC) was performed to illustrate the relationship between myocardial steatosis and LV subclinical myocardial dysfunction. Results An increase in myocardial TG content was found in the MetS group compared with that in the other groups (MetS vs. non-MetS: 1.54 ± 0.63% vs. 1.16 ± 0.45%; MetS vs. normal: 1.54 ± 0.63% vs. 0.61 ± 0.22%; all p < 0.001). Furthermore, reduced LV deformation [reduced longitudinal and radial peak strain (PS); all p < 0.017] and microvascular dysfunction [increased time to maximum signal intensity (TTM) and reduced Upslope; all p < 0.017)] was found in the MetS group. Myocardial TG content was positively associated with MetS (r = 0.314, p < 0.001), and it was independently associated with TTM (β = 0.441, p < 0.001) and LV longitudinal PS (β = 0.323, p = 0.021). ROC analysis exhibited that myocardial TG content might predict the risk of decreased LV longitudinal myocardial deformation (AUC = 0.74) and perfusion function (AUC = 0.71). Conclusion Myocardial TG content increased in T2DM patients with concurrent MetS. Myocardial steatosis was positively associated with decreased myocardial deformation and perfusion dysfunction, which may be an indicator for predicting diabetic cardiomyopathy.

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