Multidrug-Resistant Infections and Outcome of Critically Ill Patients with Coronavirus Disease 2019: A Single Center Experience

2021 ◽  
Author(s):  
Arta Karruli ◽  
Filomena Boccia ◽  
Massimo Gagliardi ◽  
Fabian Patauner ◽  
Maria Paola Ursi ◽  
...  
Keyword(s):  
Critically Ill ◽  
Critically Ill Patients ◽  
Multidrug Resistant ◽  
Single Center ◽  
Single Center Experience

scholarly journals Cost of Chronic Critically Ill Patients to the Healthcare System: A Single-center Experience from a Developing Country

2021 ◽  
Vol 25 (5) ◽  
pp. 519-523
Author(s):  
Süleyman Yıldırım ◽  
Yusuf Durmaz ◽  
Yosun Şan ◽  
İmren Taşkıran ◽  
Burcu A Cinleti ◽  
...  
Keyword(s):  
Developing Country ◽  
Critically Ill ◽  
Healthcare System ◽  
Critically Ill Patients ◽  
Single Center ◽  
Single Center Experience ◽  
System A

scholarly journals Single-Center Experience of Outcomes and Prescribing Patterns of IV Immunoglobulin Use in Critically Ill Patients

2021 ◽  
Vol 3 (1) ◽  
pp. e0314
Author(s):  
Heather Torbic ◽  
Sinan Samir Abdul-Wahab ◽  
Sravanthi Ennala ◽  
Nagamani Guduguntla ◽  
Xiaozhen Han ◽  
...  
Keyword(s):  
Critically Ill ◽  
Critically Ill Patients ◽  
Prescribing Patterns ◽  
Single Center ◽  
Single Center Experience ◽  
Iv Immunoglobulin

Predictors of Mortality in Critically Ill Patients with Poisoning: A Single Center Experience

2013 ◽  
Vol 33 (5) ◽  
pp. 1274-1282
Author(s):  
Ramazan COŞKUN ◽  
Kürşat GÜNDOĞAN ◽  
Elif ATAĞ ◽  
İsmail Hakkı AKBUDAK ◽  
Ahmet ÖZTÜRK ◽  
...  
Keyword(s):  
Critically Ill ◽  
Critically Ill Patients ◽  
Single Center ◽  
Predictors Of Mortality ◽  
Single Center Experience

scholarly journals The lower respiratory tract microbiome of critically ill patients with COVID-19

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Paolo Gaibani ◽  
Elisa Viciani ◽  
Michele Bartoletti ◽  
Russell E. Lewis ◽  
Tommaso Tonetti ◽  
...  
Keyword(s):  
Respiratory Tract ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Lower Respiratory Tract ◽  
Multidrug Resistant ◽  
Carbapenem Resistant ◽  
Lung Microbiome ◽  
Bacterial Microbiome ◽  
Unweighted Unifrac ◽  
Bacterial Superinfection

AbstractCOVID-19 infection may predispose to secondary bacterial infection which is associated with poor clinical outcome especially among critically ill patients. We aimed to characterize the lower respiratory tract bacterial microbiome of COVID-19 critically ill patients in comparison to COVID-19-negative patients. We performed a 16S rRNA profiling on bronchoalveolar lavage (BAL) samples collected between April and May 2020 from 24 COVID-19 critically ill subjects and 24 patients with non-COVID-19 pneumonia. Lung microbiome of critically ill patients with COVID-19 was characterized by a different bacterial diversity (PERMANOVA on weighted and unweighted UniFrac Pr(> F) = 0.001) compared to COVID-19-negative patients with pneumonia. Pseudomonas alcaligenes, Clostridium hiranonis, Acinetobacter schindleri, Sphingobacterium spp., Acinetobacter spp. and Enterobacteriaceae, characterized lung microbiome of COVID-19 critically ill patients (LDA score > 2), while COVID-19-negative patients showed a higher abundance of lung commensal bacteria (Haemophilus influenzae, Veillonella dispar, Granulicatella spp., Porphyromonas spp., and Streptococcus spp.). The incidence rate (IR) of infections during COVID-19 pandemic showed a significant increase of carbapenem-resistant Acinetobacter baumannii (CR-Ab) infection. In conclusion, SARS-CoV-2 infection and antibiotic pressure may predispose critically ill patients to bacterial superinfection due to opportunistic multidrug resistant pathogens.

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