Prevalence and Molecular Characterization of Extended Spectrum β-Lactamase, Plasmid-Mediated Quinolone Resistance, and Carbapenemase-Producing Gram-Negative Bacilli in Burkina Faso

2020 ◽  
Author(s):  
Soufiane Sanou ◽  
Abdoul Salam Ouedraogo ◽  
Salim Aberkane ◽  
Julie Vendrell ◽  
Oumar Ouchar ◽  
...  
Keyword(s):  
Burkina Faso ◽  
Molecular Characterization ◽  
Quinolone Resistance ◽  
Gram Negative ◽  
Extended Spectrum

scholarly journals 1667. Change in characteristics of community-onset ciprofloxacin-resistant E. coli isolates causing community-acquired acute pyelonephritis in South Korea

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S820-S820
Author(s):  
Bongyoung Kim ◽  
Ki Tae Kwon ◽  
Seong-yeol Ryu ◽  
Seong-Heon Wie ◽  
Hyun-uk Jo ◽  
...  
Keyword(s):  
Antimicrobial Resistance ◽  
South Korea ◽  
Molecular Characterization ◽  
Acute Pyelonephritis ◽  
Multilocus Sequence Typing ◽  
Quinolone Resistance ◽  
E Coli ◽  
Extended Spectrum ◽  
Community Onset

Abstract Background The aim of this study was to examine the change in characteristics of community-onset ciprofloxacin-resistant (CIP-R) E. coli isolates causing community-acquired acute pyelonephritis (CA-APN) in South Korea between 2010-2011 and 2017-2018. Methods E. coli samples isolated from the blood or urine were collected from patients with CA-APN aged 19 years and more who were admitted to 8 Korean hospitals from September 2017 to August 2018, prospectively. One isolate was collected from each patient. Phylogenetic typing, multilocus sequence typing (MLST), and molecular characterization of β-lactamase resistance and plasmid-mediated quinolone resistance (PMQR) determinants were performed. The data were compared with those from the previous study with same design in 2010-2011. Results A total of 346 and 300 isolates were collected during 2017-2018 and 2010-2011, respectively. Among them, 76 (22.0%) and 77 (25.7%) were CIP-R isolates. Significantly higher antimicrobial resistance against ampicillin (75.7% vs. 100%, P < 0.001) and cefotaxime (23.9% vs. 77.9%, P < 0.001) were observed for isolates in 2017-2018 compared to those in 2010-2011. The proportion of phylogenic group B2 had increased significantly (44.7% vs. 79.2%, P < 0.001). As for MLST, the proportion of ST131 (27.6% vs. 66.2%, P < 0.001) had increased while that of ST393 (18.4% vs. 3.9%, P =0.004) had decreased significantly. Higher proportion of CIP-R E. coli isolates in 2017-2018 had extended-spectrum β-lactamase (ESBL)/plasmid-mediated AmpC β-lactamase (PABL) (23.7% vs. 79.2%, P < 0.001) and PMQR determinant (11.8% vs. 40.8%, P < 0.001) compared to those in 2010-2011. Phlogenetic tree Analyzed by SplitsTree Conclusion Among uropathogenic CIP-R E. coli isolates in South Korea, ST131 predominance had become more prominent and the proportion of containing ESBL/PABL and/or PMQR determinants had increased. Disclosures All Authors: No reported disclosures

scholarly journals Global prevalence and molecular characterization of extended-spectrum β-lactamase producing- in dogs and cats – A scoping review and meta-analysis

One Health ◽  
2021 ◽  
pp. 100236
Author(s):  
Marília Salgado-Caxito ◽  
Julio A. Benavides ◽  
Aiko D. Adell ◽  
Antonio Carlos Paes ◽  
Andrea I. Moreno-Switt
Keyword(s):  
Molecular Characterization ◽  
Scoping Review ◽  
Meta Analysis ◽  
Global Prevalence ◽  
Extended Spectrum

scholarly journals Molecular characterization of carbapenem-resistant Gram-negative bacilli clinical isolates in Algeria

2018 ◽  
Vol Volume 11 ◽  
pp. 735-742 ◽  
Author(s):  
Nadjette Bourafa ◽  
Wafaa Chaalal ◽  
Sofiane Bakour ◽  
Rym Lalaoui ◽  
Nafissa Boutefnouchet ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Clinical Isolates ◽  
Gram Negative ◽  
Carbapenem Resistant

scholarly journals Epidemiology of multi-resistance Gram negative pathogen circulating in Liguria and molecular characterization of different carbapenemases

2011 ◽  
Vol 26 (2) ◽  
Author(s):  
Erika Coppo ◽  
Ramona Barbieri ◽  
Paolo Piazzai ◽  
Andrea Dusi ◽  
David Usiglio ◽  
...  
Keyword(s):  
Molecular Characterization ◽  
Gram Negative
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