Correlation Between Biofilm Formation and Antibiotic Resistance in MRSA and MSSA Isolated from Clinical Samples in Iran: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 26 (9) ◽  
pp. 1071-1080 ◽  
Author(s):  
Motaharesadat Hosseini ◽  
Abbas Shapouri Moghaddam ◽  
Solmaz Derakhshan ◽  
Seyed Mohammad Amin Hashemipour ◽  
Mehdi Hadadi-Fishani ◽  
...  
Keyword(s):  
Systematic Review ◽  
Antibiotic Resistance ◽  
Biofilm Formation ◽  
Meta Analysis ◽  
Clinical Samples

scholarly journals Prevalence of Class 1 Integron and Antibiotic Resistance Pattern in Pseudomonas aeruginosa Isolated from Iranian Clinical Specimens; a Systematic Review and Meta-Analysis

2019 ◽  
Author(s):  
Elham Zarifi ◽  
Yasamin Enayati Kaliji ◽  
Azad Khaledi ◽  
Mohammadreza Rahimi ◽  
Mahtab Babadi
Keyword(s):  
Systematic Review ◽  
Pseudomonas Aeruginosa ◽  
Antibiotic Resistance ◽  
Meta Analysis ◽  
Resistance Rate ◽  
Clinical Samples ◽  
Class 1 Integrons ◽  
Regression Test ◽  
Class 1 ◽  
Iranian Patients

Abstract Background The role of integrons has been shown in the horizontal transmission of antibiotic resistance genes among bacterial isolates especially Gram-negative microorganisms in clinical settings. Objectives The aim of this study was to systematically review the prevalence of class 1 integrons and antibiotic resistance in Pseudomonas aeruginosa isolates of clinical samples of Iranian patients. Methods The Web of Science, PubMed, Scopus, and Science Direct databases were searched using preferred keywords based on the Preferred Reporting Items for Systematic Review and Meta-Analyses (PRISMA) guidelines. The cross-sectional studies addressing the frequency of class 1 integrons and antibiotic‑resistance in P. aeruginosa isolates from clinical samples of Iranian patients published from 1 January 2000 until 31 December 2018 were included. Meta-analysis was performed using Comprehensive Meta-Analysis¬ (CMA) software. The random effects model was used for meta-analysis. The Cochran’s Q and I2 tests were applied for statistical analyses. Publication bias was assessed using Funnel plot and Egger’s linear regression test. Results Out of 911 studies retrieved in the initial search, 17 articles met the eligibility standards for being included in the meta-analysis. The Egger’s linear regression test indicated no publication bias (P = 0.95). The combined prevalence of class 1 integrons in P. aeruginosa isolates was obtained as 58.9% (95% CI: 46.3–70.4%). The highest rate of combined antibiotic resistance was related to Carbenicillin with a resistance rate of 79.9%. On the other side, the most effective antibiotic against P. aeruginosa was Polymyxin B with the resistance rate of 0%. The pooled prevalence of multi-drug resistant (MDR) P. aeruginosa isolates was 55% (¬95% CI: 33.8-75.3%). Conclusions Our findings indicated the high prevalence of class 1 integrons and antibiotic resistance among P. aeruginosa isolates of Iranian patients’ clinical samples. Also, the prevalence of MDR P. aeruginosa isolates was noticeable requiring prompt action.

Comments on the published systematic review and meta-analysis on the increasing antibiotic resistance in Clostridioides difficile

Anaerobe ◽  
2020 ◽  
Vol 61 ◽  
pp. 102141
Author(s):  
Ebrahim Kouhsari ◽  
Sara Hayati Mehr ◽  
Mohammad Sholeh ◽  
Nima Mohammadzadeh
Keyword(s):  
Systematic Review ◽  
Antibiotic Resistance ◽  
Meta Analysis ◽  
Clostridioides Difficile

scholarly journals A global perspective of antibiotic-resistant Listeria monocytogenes prevalence in assorted ready to eat foods: A systematic review

2021 ◽  
pp. 2219-2229
Author(s):  
Prudence Mpundu ◽  
Allan Rabson Mbewe ◽  
John Bwalya Muma ◽  
Wizaso Mwasinga ◽  
Nawa Mukumbuta ◽  
...  
Keyword(s):  
Systematic Review ◽  
Antibiotic Resistance ◽  
Listeria Monocytogenes ◽  
Meta Analysis ◽  
Global Perspective ◽  
Valuable Insight ◽  
Resistance Profile ◽  
Antibiotic Resistance Profile ◽  
Pooled Prevalence ◽  
Insight Into

Background and Aim: Listeria monocytogenes in ready-to-eat (RTE) foods remains consistently under-reported globally. Nevertheless, several independent studies conducted to investigate have elucidated the prevalence and antibiotic resistance profiles of L. monocytogenes in RTE-associated foods and their antibiotic resistance profiles. Given the rapid increase in consumption of RTE foods of both animal and plant origin, it is imperative to know the prevalence deductive data focusing on how much of L. monocytogenes is present in RTE foods, which is critical for food safety managers and retailers to assess the possible risk posed to end-users. In addition, valuable insight and another angle to the depth of the problem, we conducted a systematic review and meta-analysis to synthesize available data regarding the prevalence of L. monocytogenes in RTE foods and antibiotic resistance profiles. Materials and Methods: We conducted a meta-analysis study of L. monocytogenes and antibiotic resistance to clinically relevant antibiotics to determine the extent of L. monocytogenes contamination in RTE foods and antibiotic resistance profiles. The primary search terms, also known as keywords used, were restricted to peer-reviewed and review articles, and databases, including Google Scholars, Science-Direct, and Scopus, were searched. The inclusion of articles meeting eligibility criteria published between 2010 and 2020 after title, abstract, and full article screening. Data analysis was performed at multiple stages using quantitative meta-analysis reviews. Results: L. monocytogenes pooled proportion/prevalence was highest in chicken products determined at (22%) followed by various but uncategorized RTE foods at 21%. Regarding antibiotic resistance, profiling's highest pooled prevalence resistance was observed in penicillin at 80% resistance, followed by cephalosporin at 47%. Conclusion: Within its limitations, this study has attempted to provide insight into the pooled proportion/prevalence of L. monocytogenes in RTE foods and the antibiotic resistance profile at the global level. Determining the proportion/ prevalence of L. monocytogenes in RTE foods across the globe and antibiotic resistance profile is essential for providing quality food and reducing public health problems due to unsuccessful treatment of foodborne illness. This study provides insight into the pooled prevalence of L. monocytogenes in RTE foods and the antibiotic resistance profile. The results of this study partly endeavored to help appropriate authorities strengthen their preventive measures on specific RTE foods that are most likely to be contaminated with L. monocytogenes and antibiotic resistance profiles.

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