Prevalence of Genes Encoding Aminoglycoside-Modifying Enzymes in Clinical Isolates of Gram-Positive Cocci in Iran: A Systematic Review and Meta-Analysis

2020 ◽  
Vol 26 (2) ◽  
pp. 126-135
Author(s):  
Reza Beigverdi ◽  
Azin Sattari-Maraji ◽  
Fereshteh Jabalameli ◽  
Mohammad Emaneini
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Clinical Isolates ◽  
Gram Positive ◽  
Genes Encoding ◽  
Gram Positive Cocci

The prevalence of genes encoding ESBL among clinical isolates of Escherichia coli in Iran: A systematic review and meta-analysis

Gene Reports ◽  
2020 ◽  
Vol 18 ◽  
pp. 100562 ◽  
Author(s):  
Roya Saddat Ghaderi ◽  
Atieh Yaghoubi ◽  
Razieh Amirfakhrian ◽  
Seyed Isaac Hashemy ◽  
Kiarash Ghazvini
Keyword(s):  
Escherichia Coli ◽  
Systematic Review ◽  
Meta Analysis ◽  
Clinical Isolates ◽  
Genes Encoding

Evaluation of the sodium polyanethol sulfonate disk test for the identification of Peptostreptococcus anaerobius

1976 ◽  
Vol 4 (4) ◽  
pp. 330-333
Author(s):  
P A Wideman ◽  
V L Vargo ◽  
D Citronbaum ◽  
S M Finegold
Keyword(s):  
Inhibition Zone ◽  
Clinical Isolates ◽  
Normal Flora ◽  
Gram Positive ◽  
Inoculum Sources ◽  
Clinical Specimens ◽  
Test Conditions ◽  
Inhibition Zones ◽  
Gram Positive Cocci ◽  
Disk Test

The previously reported sodium polyanethol sulfonate disk test for the identification of Peptostreptococcus anaerobius (Graves et al., 1974) was evaluated, with modifications. Three bands of brucella agar, three inoculum sizes, and two inoculum sources were compared. Nine stock cultures of P. anaerobius (eight normal flora isolates and ATCC 27337) and 16 fresh clinical isolates were used. All cultures of P. anaerobius showed inhibition zones of 12 to 30 mm in diameter, regardless of test conditions. Out of 103 clinical isolates of other species of anaerobic gram-positive cocci tested, only two had an inhibition zone size in this range (one P. micros of 11 studied had a zone of 12 mm and one P. prevotii of 14 studied had a zone of 16). The test had an overall accuracy of 98% in the identification of P. anaerobius from clinical specimens. Since P. anaerobius accounts for one-fifth to one-third of all anaerobic gram-positive cocci encountered in clinical specimens, this simple and rapid technique can be very useful for presumptive identification.

scholarly journals Prevalence of the Genus Propionibacterium in Primary and Persistent Endodontic Lesions: A Systematic Review

2020 ◽  
Vol 9 (3) ◽  
pp. 739 ◽  
Author(s):  
Mario Dioguardi ◽  
Mario Alovisi ◽  
Vito Crincoli ◽  
Riccardo Aiuto ◽  
Giancarlo Malagnino ◽  
...  
Keyword(s):  
Systematic Review ◽  
Propionibacterium Acnes ◽  
Meta Analysis ◽  
Secondary Outcome ◽  
Exclusion Criteria ◽  
Gram Positive ◽  
Gram Positive Bacteria ◽  
Endodontic Infections ◽  
Outcome Differences ◽  
Present Systematic Review

Propionibacterium are anaerobic/aero-tolerant rod Gram-positive bacteria, and numerous studies are associated with primary and secondary endodontic infections. The data in the literature on the prevalence of Propionibacterium are conflicting, and there are studies that report conflicting data on the prevalence in primary and secondary endodontic infections. This review aims to clarify the prevalence of bacteria of the genus Propionibacterium in endodontic lesions. The present systematic review work was performed on the basis of the Prisma protocol. A search was carried out on the PubMed and Scopus databases with the use of keywords. The research produced 410 records, which, after the elimination of the overlaps and the application of the inclusion and exclusion criteria, led to a number of 36 included articles divided by the three outcomes. The first outcome concerns prevalence of bacteria of the genus Propionibacterium in primary and secondary endodontic lesions. The secondary outcome, differences in the prevalence of bacteria of the genus Propionibacterium between primary endodontic infections and secondary endodontic infections. The tertiary outcome, differences in the prevalence of Propionibacterium Acnes compared to Propionibacterium propionicum in endodontic infections. The results of the meta-analysis show that the genus Propionibacterium bacteria are more prevalent in secondary endodontic infections and that P. acnes has a higher prevalence than P. propionicum.

scholarly journals Role of extracorporeal membrane oxygenation in children with sepsis: a systematic review and meta-analysis

Critical Care ◽  
2020 ◽  
Vol 24 (1) ◽  
Author(s):  
Kollengode Ramanathan ◽  
Nicholas Yeo ◽  
Peta Alexander ◽  
Lakshmi Raman ◽  
Ryan Barbaro ◽  
...  
Keyword(s):  
Systematic Review ◽  
Septic Shock ◽  
Extracorporeal Membrane Oxygenation ◽  
Survival Data ◽  
Meta Analysis ◽  
Survival Rates ◽  
Hospital Length Of Stay ◽  
Secondary Outcome ◽  
Gram Positive ◽  
Membrane Oxygenation

Abstract Background The benefits of extracorporeal membrane oxygenation (ECMO) in children with sepsis remain controversial. Current guidelines on management of septic shock in children recommend consideration of ECMO as salvage therapy. We sought to review peer-reviewed publications on effectiveness of ECMO in children with sepsis. Methods Studies reporting on mortality in children with sepsis supported with ECMO, published in PubMed, Scopus and Embase from 1972 till February 2020, were included in the review. This study was done in adherence to Preferred Reporting Items for Systematic Review and Meta-Analysis statement after registering the review protocol with PROSPERO. Study eligibility was independently assessed by two authors and disagreements resolved by a third author. Publications were reviewed for quality using Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system. Random-effects meta-analyses (DerSimonian and Laird) were conducted, and 95% confidence intervals were computed using the Clopper-Pearson method. Outliers were identified by the Baujat plot and leave-one-out analysis if there was considerable heterogeneity. The primary outcome measure was survival to discharge. Secondary outcome measures included hospital length of stay, subgroup analysis of neonatal and paediatric groups, types and duration of ECMO and complications . Results Of the 2054 articles screened, we identified 23 original articles for systematic review and meta-analysis. Cumulative estimate of survival (13 studies, 2559 patients) in the cohort was 59% (95%CI: 51–67%). Patients had a median length of hospital stay of 28.8 days, median intensive care unit stay of 13.5 days, and median ECMO duration of 129 h. Children needing venoarterial ECMO (9 studies, 208 patients) showed overall pooled survival of 65% (95%CI: 50–80%). Neonates (< 4 weeks of age) with sepsis needing ECMO (7 studies, 85 neonates) had pooled survival of 73% (95%CI: 56- 87%). Gram positive organisms were the most common pathogens (47%) in septic children supported with ECMO. Conclusion Survival rates of children with sepsis needing ECMO was 59%. Neonates had higher survival rates (73%); gram positive organisms accounted for most common infections in children needing ECMO. Despite limitations, pooled survival data from this review indicates consideration of ECMO in refractory septic shock for all pediatric age groups.

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