A High Frequency of Macrolide-Lincosamide-Streptogramin Resistance Determinants in Staphylococcus aureus Isolated in South Korea

2004 ◽  
Vol 10 (3) ◽  
pp. 248-254 ◽  
Author(s):  
Hong Bin Kim ◽  
Bobin Lee ◽  
Hee-Chang Jang ◽  
Sung Han Kim ◽  
Cheol In Kang ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
South Korea ◽  
High Frequency ◽  
Resistance Determinants

A High Frequency of Macrolide-Lincosamide-Streptogramin Resistance Determinants in Staphylococcus aureus Isolated in South Korea

2004 ◽  
Vol 10 (3) ◽  
pp. 248-254
Author(s):  
Hong Bin Kim ◽  
Bobin Lee ◽  
Hee-Chang Jang ◽  
Sung Han Kim ◽  
Cheol In Kang ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
South Korea ◽  
High Frequency ◽  
Resistance Determinants

scholarly journals Vaccine-Related Errors in Reconstitution in South Korea: A National Physicians’ and Nurses’ Survey

Vaccines ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 117
Author(s):  
Young Hwa Lee ◽  
Rebecca C. Harris ◽  
Hong Won Oh ◽  
Yongho Oh ◽  
Juan C. Vargas-Zambrano ◽  
...  
Keyword(s):  
South Korea ◽  
High Frequency ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Vaccine Preparation

Vaccine-related errors (VREs) result from mistakes in vaccine preparation, handling, storage, or administration. We aimed to assess physicians’ and nurses’ experiences of VREs in South Korea, focusing on reconstitution issues, and to understand the barriers to and facilitators of preventing them. This was a cross-sectional study using an internet-based survey to examine experiences of reconstitution-related errors, and experience or preference with regard to ready-to-use vaccines (RTU) by physicians and nurses. A total of 700 participants, including 250 physicians and 450 nurses, responded to the questionnaire. In total, 76.4% and 41.5% of the physicians and nurses, respectively, reported an error related to reconstituted vaccines. All errors had been reported as experienced by between 4.9% and 52.0% of physicians or nurses. The errors were reported to occur in more than one in 100 vaccinations for inadequate shaking of vaccines by 28.0% of physicians and 6.9% of nurses, incomplete aspiration of reconstitution vials by 28.0% of physicians and 6.4% of nurses, and spillage or leakage during reconstitution by 20.8% of physicians and 6.9% of nurses. A total of 94.8% of physicians had experience with RTU vaccines, and all preferred RTU formulations. In conclusion, this study highlights the high frequency and types of reconstitution-related errors in South Korea. RTU vaccines could help reduce the time needed for preparation and reduce the risk of errors in South Korea.

scholarly journals No Change, No Life? What We Know about Phase Variation in Staphylococcus aureus

2021 ◽  
Vol 9 (2) ◽  
pp. 244
Author(s):  
Vishal Gor ◽  
Ryosuke L. Ohniwa ◽  
Kazuya Morikawa
Keyword(s):  
Gene Expression ◽  
Staphylococcus Aureus ◽  
High Frequency ◽  
Direct Evidence ◽  
Bacterial Species ◽  
Phase Variation ◽  
Opportunistic Pathogen ◽  
Adaptation Strategy ◽  
Innate Immune ◽  
Epigenetic Mechanisms

Phase variation (PV) is a well-known phenomenon of high-frequency reversible gene-expression switching. PV arises from genetic and epigenetic mechanisms and confers a range of benefits to bacteria, constituting both an innate immune strategy to infection from bacteriophages as well as an adaptation strategy within an infected host. PV has been well-characterized in numerous bacterial species; however, there is limited direct evidence of PV in the human opportunistic pathogen Staphylococcus aureus. This review provides an overview of the mechanisms that generate PV and focuses on earlier and recent findings of PV in S. aureus, with a brief look at the future of the field.

scholarly journals Draft Genome Sequences of Lysostaphin-Resistant (K07-204) and Lysostaphin-Susceptible (K07-561) Staphylococcus aureus Sequence Type 72 Strains Isolated from Patients in South Korea

2020 ◽  
Vol 9 (49) ◽  
Author(s):  
Nayab Batool ◽  
Kwan Soo Ko ◽  
Akhilesh Kumar Chaurasia ◽  
Kyeong Kyu Kim
Keyword(s):  
Staphylococcus Aureus ◽  
South Korea ◽  
Genome Sequencing ◽  
Draft Genome ◽  
Sequence Type ◽  
Genome Sequences ◽  
Content Type ◽  
Subtractive Genomics ◽  
Draft Genome Sequencing ◽  
Different Levels

ABSTRACT Methicillin-resistant Staphylococcus aureus sequence type 72 (ST72) is prevalent in South Korea and has shown resistance to multiple antimicrobials. ST72 isolates display different levels of resistance to the antistaphylococcal lysostaphin. Draft genome sequencing of ST72 human isolates exhibiting lysostaphin resistance or susceptibility was performed to better understand the mechanism of lysostaphin resistance using subtractive genomics.

scholarly journals Multiply- and methicillin-resistantStaphylococcus aureusstrains isolated in the German Democratic Republic in 1985 and 1986

1987 ◽  
Vol 99 (3) ◽  
pp. 603-612 ◽  
Author(s):  
W. Witte ◽  
Chr. Braulke
Keyword(s):  
Staphylococcus Aureus ◽  
Nosocomial Infection ◽  
Democratic Republic ◽  
Phage Typing ◽  
Biochemical Traits ◽  
Strain Differentiation ◽  
Resistance Determinants ◽  
Basic Set ◽  
Resistant Strains ◽  
Mrsa Strains

SUMMARYMultiply- and methicillin-resistantStaphylococcus aureus(MRSA) strains have been isolated from five small outbreaks of nosocomial infection in five different hospitals. The MRSA were typed by phage patterns, biochemical traits, resistance phenotypes and plasmid patterns. Three different groups of strains can be distinguished. The MRSA from three outbreaks in one country share identical characters.Phage typing by the use of the International Basic Set for Phage Typing staphylococci as well as experimental phages does not completely discriminate between the strains. Attribution of several resistance determinants to plasmids in two of the described strain groups proved valuable for strain differentiation.These multiply-resistant strains are sensitive to vancomycin and to rifampicin.

scholarly journals Regulation of the Expression of the β-Lactam Antibiotic-Resistance Determinants in Methicillin-Resistant Staphylococcus aureus (MRSA)

Biochemistry ◽  
2014 ◽  
Vol 53 (10) ◽  
pp. 1548-1550 ◽  
Author(s):  
Blas Blázquez ◽  
Leticia I. Llarrull ◽  
Juan R. Luque-Ortega ◽  
Carlos Alfonso ◽  
Bill Boggess ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Antibiotic Resistance ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Methicillin Resistant ◽  
Resistance Determinants ◽  
Lactam Antibiotic
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