scholarly journals Identification of the Lymphatic Drainage Pattern of Esophageal Cancer with Near-Infrared Fluorescent Imaging

2017 ◽  
Vol 27 (3) ◽  
pp. 268-271 ◽  
Author(s):  
Francisco Schlottmann ◽  
Arianna Barbetta ◽  
Benedetto Mungo ◽  
Anne O. Lidor ◽  
Daniela Molena
Keyword(s):  
Esophageal Cancer ◽  
Near Infrared ◽  
Lymphatic Drainage ◽  
Fluorescent Imaging ◽  
Drainage Pattern ◽  
Lymphatic Drainage Pattern

91 poster: Investigating the Impact of the Highly Variable Lymphatic Drainage Pattern in Prostate Cancer Patients

2010 ◽  
Vol 94 ◽  
pp. S35
Author(s):  
L. Van den Bergh ◽  
C. Deroose ◽  
S. Joniau ◽  
T. Budiharto ◽  
F. Mottaghy ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Cancer Patients ◽  
Lymphatic Drainage ◽  
Drainage Pattern ◽  
The Impact ◽  
Lymphatic Drainage Pattern

scholarly journals Near-infrared fluorescent imaging with indocyanine green in rabbit and patient specimens of esophageal cancer

2021 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Jiyun Rho ◽  
Yu Hua Quan ◽  
Byeong Hyeon Choi ◽  
Kook Nam Han ◽  
Beop-Min Kim ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Indocyanine Green ◽  
Near Infrared ◽  
Fluorescent Imaging

Fluorescent proteins for in vivo imaging, where's the biliverdin?

2020 ◽  
Vol 48 (6) ◽  
pp. 2657-2667
Author(s):  
Felipe Montecinos-Franjola ◽  
John Y. Lin ◽  
Erik A. Rodriguez
Keyword(s):  
Hydrogen Peroxide ◽  
In Vivo Imaging ◽  
Near Infrared ◽  
Fluorescent Protein ◽  
Fluorescent Proteins ◽  
Fluorescent Imaging ◽  
Infrared Light ◽  
Red Fluorescent Protein ◽  
Color Palette

Noninvasive fluorescent imaging requires far-red and near-infrared fluorescent proteins for deeper imaging. Near-infrared light penetrates biological tissue with blood vessels due to low absorbance, scattering, and reflection of light and has a greater signal-to-noise due to less autofluorescence. Far-red and near-infrared fluorescent proteins absorb light >600 nm to expand the color palette for imaging multiple biosensors and noninvasive in vivo imaging. The ideal fluorescent proteins are bright, photobleach minimally, express well in the desired cells, do not oligomerize, and generate or incorporate exogenous fluorophores efficiently. Coral-derived red fluorescent proteins require oxygen for fluorophore formation and release two hydrogen peroxide molecules. New fluorescent proteins based on phytochrome and phycobiliproteins use biliverdin IXα as fluorophores, do not require oxygen for maturation to image anaerobic organisms and tumor core, and do not generate hydrogen peroxide. The small Ultra-Red Fluorescent Protein (smURFP) was evolved from a cyanobacterial phycobiliprotein to covalently attach biliverdin as an exogenous fluorophore. The small Ultra-Red Fluorescent Protein is biophysically as bright as the enhanced green fluorescent protein, is exceptionally photostable, used for biosensor development, and visible in living mice. Novel applications of smURFP include in vitro protein diagnostics with attomolar (10−18 M) sensitivity, encapsulation in viral particles, and fluorescent protein nanoparticles. However, the availability of biliverdin limits the fluorescence of biliverdin-attaching fluorescent proteins; hence, extra biliverdin is needed to enhance brightness. New methods for improved biliverdin bioavailability are necessary to develop improved bright far-red and near-infrared fluorescent proteins for noninvasive imaging in vivo.

Lysosomal targeted NIR photosensitizer for photodynamic therapy and two-photon fluorescent imaging

2021 ◽  
Author(s):  
Ruiyuan Liu ◽  
Yuping Zhou ◽  
Di Zhang ◽  
Genghan He ◽  
Chuang Liu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Fluorescence Imaging ◽  
Near Infrared ◽  
Fluorescent Imaging ◽  
High Fidelity ◽  
Design And Synthesis ◽  
Two Photon ◽  
Two Photon Fluorescence ◽  
Photon Fluorescence

Design and synthesis of near-infrared (NIR) emissive fluorophore for imaging of organelle and photodynamic therapy has received enormous attention. Hence, NIR emissive fluorophore of high-fidelity lysosome targeting, two-photon fluorescence imaging,...

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