Endoscopy-Assisted Laparoscopic Resections for Gastric Gastrointestinal Stromal Tumors: A Retrospective Study

2017 ◽  
Vol 27 (2) ◽  
pp. 110-114 ◽  
Author(s):  
Jiang-Long Huang ◽  
Zong-Heng Zheng ◽  
Hong-Bo Wei ◽  
Tu-Feng Chen ◽  
Jian-Pei Liu ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Gastrointestinal Stromal Tumors ◽  
Stromal Tumors

Laparoscopic Versus Open Resection of Gastric Gastrointestinal Stromal Tumors Larger Than 5 cm: A Single-Center, Retrospective Study

2017 ◽  
Vol 24 (6) ◽  
pp. 582-589 ◽  
Author(s):  
Guanglin Qiu ◽  
Jing Wang ◽  
Xiangming Che ◽  
Shicai He ◽  
Chao Wei ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Gastrointestinal Stromal Tumors ◽  
Single Center ◽  
Open Resection ◽  
Stromal Tumors

2283 Resection of liver metastasis in patients with gastrointestinal stromal tumors in the imatinib era: A nationwide retrospective study

2015 ◽  
Vol 51 ◽  
pp. S427
Author(s):  
R. Tielen ◽  
M. Seesing ◽  
R. Van Hillegersberg ◽  
C. Verhoef ◽  
F. Van Coevorden ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Liver Metastasis ◽  
Gastrointestinal Stromal Tumors ◽  
Stromal Tumors

scholarly journals Outcomes of First-Line Chemotherapy in Patients with Advanced or Metastatic Leiomyosarcoma of Uterine and Non-Uterine Origin

Sarcoma ◽  
2009 ◽  
Vol 2009 ◽  
pp. 1-6 ◽  
Author(s):  
A. W. Oosten ◽  
C. Seynaeve ◽  
P. I. M. Schmitz ◽  
M. A. den Bakker ◽  
J. Verweij ◽  
...  
Keyword(s):  
Overall Survival ◽  
Retrospective Study ◽  
Gastrointestinal Stromal Tumors ◽  
Overall Response Rate ◽  
Response Rate ◽  
Soft Tissue Sarcomas ◽  
Histological Subtype ◽  
First Line ◽  
Stromal Tumors ◽  
Line Chemotherapy

Although leiomyosarcomas (LMSs) form the largest subgroup of soft tissue sarcomas (STSs), the efficacy of chemotherapy in this group is largely unclear, partly because older studies are contaminated with gastrointestinal stromal tumors (GISTs). In this retrospective study we investigated the outcome of first line chemotherapy in 65 patients with unresectable or metastatic LMS. The overall response rate (ORR) was 18%; and the median progression-free (PFS) and overall survival (OS) were 3.8 and 9.7 months respectively. No statistically significant differences in outcomes for uterine and non-uterine LMS were found. In non-uterine LMS, however, the PFS and OS seemed to be longer for females than for males, potentially negatively affecting outcomes in this group. If our observations are confirmed in other series, they would suggest that studies performed in STS patients should not only stratify for histological subtype but also for uterine versus non-uterine LMS and for gender.

scholarly journals Role of Multidetector CT Imaging in the Risk Stratification of Gastrointestinal Stromal Tumors (GISTs)–A Retrospective Analysis

2021 ◽  
Vol 04 (01) ◽  
pp. 014-023
Author(s):  
Geena Benjamin ◽  
Thara Pratap ◽  
Mangalanandan Sreenivasan ◽  
Dhanya Jacob ◽  
Agnes Thomas ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Risk Stratification ◽  
Gastrointestinal Stromal Tumors ◽  
Multidetector Ct ◽  
Subsequent Development ◽  
Maximum Size ◽  
Adjacent Organ ◽  
Stromal Tumors ◽  
Imaging Characteristics

Abstract Background Gastrointestinal stromal tumors (GISTs) are the most common gastrointestinal mesenchymal neoplasms which can arise from any part of the gastrointestinal tract (GIT) or an extraintestinal location. Size and the organ of origin are the major imaging inputs expected from the radiologist. However, it is worthwhile to find out which imaging characteristics on MDCT correlate with risk stratification. This knowledge would help the clinician in treatment planning and prognostication. The aim of this retrospective study is to evaluate the various MDCT imaging characteristics of GISTs and find out which parameters have significant association with risk and subsequent development of metastasis on follow-up whenever it was possible. Materials and Methods This is a retrospective study conducted on 45 histopathologically proven cases of GIST from two institutions by searching from the digital archives. The following imaging parameters were analyzed: maximum size in any plane, organ of origin, shape (round, ovoid or irregular), margin (well-defined or ill-defined), surface (smooth or lobulated), percentage of necrosis, growth pattern, enhancement characteristics–both intensity (mild, moderate or significant) and pattern (homogenous vs. heterogenous), calcification, infiltration into adjacent organs, and presence of metastasis at presentation or on follow-up. Results CT morphological parameters of significance in risk stratification as per our study include tumor necrosis, predominant cystic change, irregular and lobulated shape/surface characteristics, and adjacent organ infiltration.The parameters which were associated with development of metastasis were size > 5 cm, necrosis > 30%, and the presence of adjacent organ infiltration. Conclusion The radiologist has an important role in ascertaining the size of tumor as well as the organ of origin accurately to guide the clinician in risk calculation and subsequent prognostication. In addition, certain CT characteristics mentioned above, namely, tumor size, significant necrosis/cystic changes, irregular/lobulated contour, and invasion of adjacent organs, help in risk stratification and in predicting metastasis/poor prognosis.

Is There a Place for Thoracoscopic Enucleation of Esophageal Gastrointestinal Stromal Tumors?

2018 ◽  
Vol 67 (07) ◽  
pp. 585-588 ◽  
Author(s):  
Charlotte Cohen ◽  
Daniel Pop ◽  
Philippe Icard ◽  
Jean-Philippe Berthet ◽  
Nicolas Venissac ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Gastrointestinal Stromal Tumors ◽  
Postoperative Morbidity ◽  
Oncological Outcome ◽  
Intermediate Risk ◽  
Invasive Treatment ◽  
High Power Field ◽  
Stromal Tumors ◽  
Thoracoscopic Enucleation

Background Esophageal gastrointestinal stromal tumors (E-GISTs) represent less than 1% of all GISTs. The rarity of this lesion precludes the realization of randomized studies, and its treatment remains a matter of debate. We aimed to evaluate the feasibility of enucleation by video-assisted thoracic surgery (VATS) for low- to intermediate-risk E-GIST. Methods We performed a retrospective review of patients treated by enucleation through VATS between January 2004 and January 2014 and reviewed the literature. Results We included five patients (four men and one woman). Mean age was 53 years (range: 49–79). Three patients were diagnosed because of dysphagia and two others incidentally. The diagnosis was made by immunostaining demonstrating CD117 expression on tumor cells. The mitotic index of all E-GISTs was low (≤ 5 per 50 high-power field). Median postoperative follow-up was 5.5 years, and there was no recurrence. Conclusion Thoracoscopic enucleation of E-GIST seems to represent a valuable option as the postoperative morbidity/mortality is low and the oncological outcome is good for low-to-intermediate grade of malignity tumors.This is a retrospective study focused on minimally invasive treatment of E-GIST. We evaluated the feasibility of VATS enucleation of low-to-medium grade of malignity E-GIST.

Selective indications of surgery in esophageal gastrointestinal stromal tumors: A retrospective study of the French Sarcoma Group (FSG).

2015 ◽  
Vol 33 (15_suppl) ◽  
pp. 10534-10534
Author(s):  
Florence Duffaud ◽  
Pierre Meeus ◽  
Francois Bertucci ◽  
jean-Baptiste Delhorme ◽  
Eberhard Stoeckle ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Gastrointestinal Stromal Tumors ◽  
Stromal Tumors
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