Therapeutic Effects of Laparoscopic Splenectomy and Esophagogastric Devascularization on Liver Cirrhosis and Portal Hypertension in 204 Cases

2014 ◽  
Vol 24 (9) ◽  
pp. 612-616 ◽  
Author(s):  
Zhe Cheng ◽  
Jian-wei Li ◽  
Jian Chen ◽  
Yu-dong Fan ◽  
Peng Guo ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Portal Hypertension ◽  
Laparoscopic Splenectomy ◽  
Therapeutic Effects

Effect of laparoscopic splenectomy on portal haemodynamics in patients with liver cirrhosis and portal hypertension

2014 ◽  
Vol 101 (12) ◽  
pp. 1585-1593 ◽  
Author(s):  
H. Kawanaka ◽  
T. Akahoshi ◽  
N. Kinjo ◽  
T. Iguchi ◽  
M. Ninomiya ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Portal Hypertension ◽  
Laparoscopic Splenectomy

scholarly journals Liver Retraction Using n-Butyl-2-Cyanoacrylate (NBCA) Glue during Laparoscopic Splenectomy and Azygoportal Disconnection in Cirrhotic Patients

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Du Kong ◽  
Wei Wang ◽  
Gang Du ◽  
Binyao Shi ◽  
Zhengchen Jiang ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Portal Hypertension ◽  
Liver Function ◽  
Blood Loss ◽  
Laparoscopic Splenectomy ◽  
Postoperative Bleeding ◽  
Gastroesophageal Varices ◽  
Liver Retraction ◽  
Significant Difference ◽  
Cirrhotic Patients

Background. Although liver retraction using n-butyl-2-cyanoacrylate (NBCA) glue has been applied to laparoscopic upper abdominal surgery in noncirrhotic patients, there is still no consensus on its safety and feasibility for cirrhotic patients. In this study, we aimed to investigate the safety and effectiveness of liver retraction using NBCA glue during laparoscopic splenectomy and azygoportal disconnection (LSD) for gastroesophageal varices and hypersplenism secondary to liver cirrhosis and portal hypertension. Methods. Thirty-nine gastroesophageal varices and hypersplenism secondary to liver cirrhosis and portal hypertension patients were included in our study. We performed LSD in the presence of NBCA glue (n = 22, NBCA group) and absence of NBCA glue (n = 17, n-NBCA group), respectively. The operation time, blood loss, postoperative hospitalization, and liver function were compared between the two groups. Results. There was no mortality during the operation. One patient in non-NBCA group received open surgery due to parenchyma hemorrhage. Postoperative pleural effusion occurred in 2 cases of the NBCA group and 1 of the non-NBCA group. One showed left subphrenic abscess in the non-NBCA group. No postoperative bleeding occurred after 9-30 months of follow-up. The time of operation in NBCA group was significantly shorter than those in n-NBCA group (198.86±17.86 versus 217.81±20.25min, P<0.01). Blood loss in NBCA group was significantly lower than non-NBCA group (159.09±56.98 versus 212.50±88.51 ml, P<0.05). The levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were increased on day 1 after LSD and decreased to normal level on day 7 after LSD in both groups. There was no significant difference in postoperative hospitalization and liver function between the two groups. Conclusion. Liver retraction using NBCA glue during LSD for gastroesophageal varices and hypersplenism secondary to liver cirrhosis and portal hypertension is safe, effective, and feasible.

Splenic Bed Laparoscopic Splenectomy Approach for Massive Splenomegaly Secondary to Portal Hypertension and Liver Cirrhosis

2018 ◽  
Vol 84 (6) ◽  
pp. 1033-1038 ◽  
Author(s):  
Guangjin Tian ◽  
Deyu Li ◽  
Haibo Yu ◽  
Yadong Dong ◽  
Huanzhou Xue
Keyword(s):  
Liver Cirrhosis ◽  
Portal Hypertension ◽  
Laparoscopic Splenectomy ◽  
Postoperative Bleeding ◽  
Operation Time ◽  
Massive Splenomegaly ◽  
Conversion To Open Surgery ◽  
Transfusion Volume ◽  
Pugh Class ◽  
Short Gastric Vessels

This study was performed to evaluate the feasibility of the splenic bed laparoscopic splenectomy approach (SBLS) for massive splenomegaly (≥30 cm) in patients with hypersplenism secondary to portal hypertension and liver cirrhosis. Patients who underwent laparoscopic splenectomy (LS) from January 2012 to December 2016 were retrospectively reviewed. We performed LS in 83 patients with massive splenomegaly (≥30 cm) secondary to portal hypertension and liver cirrhosis. Of these patients, 37 underwent the SBLS and 46 underwent anterior LS (ALS). Five patients in the ALS group and none in the SBLS group underwent conversion to open surgery. The operation time, intraoperative blood loss volume, transfusion volume, frequency of transfusion, hemorrhage of short gastric vessels, conversion rate, postoperative hospital stay, and incidence of pancreatic fistula were all significantly lower in the SBLS than ALS group (all P < 0.05). No death or postoperative bleeding occurred in the two groups, and there were no significant differences in age, gender, spleen size, hemoglobin level, platelet count, prothrombin time, Child-Pugh class, hypoproteinemia, or ascites (all P > 0.05). The SBLS is more feasible and effective than ALS in patients with massive splenomegaly (≥30 cm) secondary to portal hypertension and liver cirrhosis.

scholarly journals Laparoscopic splenectomy with or without devascularization of the stomach for liver cirrhosis and portal hypertension: a systematic review

2012 ◽  
Vol 83 (3) ◽  
pp. 122-128 ◽  
Author(s):  
Xiao-Dong Chen ◽  
Fu-Qian He ◽  
Lie Yang ◽  
Yong-Yang Yu ◽  
Zong-Guang Zhou
Keyword(s):  
Systematic Review ◽  
Liver Cirrhosis ◽  
Portal Hypertension ◽  
Laparoscopic Splenectomy
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