Laparoscopy-Assisted Single-Port Appendectomy in Children: Is the Postoperative Infectious Complication Rate Different?

2010 ◽  
Vol 20 (10) ◽  
pp. 867-871 ◽  
Author(s):  
Sergio B. Sesia ◽  
Frank-Martin Haecker ◽  
Rainer Kubiak ◽  
Johannes Mayr
Keyword(s):  
Complication Rate ◽  
Infectious Complication ◽  
Single Port ◽  
Postoperative Infectious Complication

Laparoscopic versus Open Appendectomy: Is the Postoperative Infectious Complication Rate Different?

2005 ◽  
Vol 71 (10) ◽  
pp. 813-815 ◽  
Author(s):  
Francesca Hoehne ◽  
Maria Ozaeta ◽  
Bill Sherman ◽  
Peter Miani ◽  
Edward Taylor
Keyword(s):  
Blood Cell ◽  
Cell Count ◽  
White Blood Cell Count ◽  
White Blood Cell ◽  
Complication Rate ◽  
Infectious Complication ◽  
Open Appendectomy ◽  
Perforated Appendicitis ◽  
Postoperative Infectious Complication ◽  
Blood Cell Count

Despite the reported advantages of laparoscopic appendectomy (LA), there is debate about the postoperative infectious complication rate. Our study attempts to determine if the infectious complication rate between LA and open appendectomy (OA) is different. A retrospective review was conducted of all patients who underwent appendectomy at Kern Medical Center between 1999 and 2003. Age, sex, white blood cell count, temperature, pathology, and postoperative complications were identified. Fifty-seven patients underwent LA, and 159 patients underwent OA. The groups were well matched for demographics, white blood cell count, temperature, and percent perforated appendicitis. There was an overall 9.3 per cent complication rate. The infectious complication rate in OA versus LA group was statistically different (6.3% vs 17.6%, P = 0.04). The infectious complication rate in the LA group was significantly higher than in the OA group. Further large randomized trials are necessary to confirm our findings and to identify if LA is appropriate for a subset of appendicitis patients.

#49: Results of 10 Years of Peripherally Inserted Central Catheter Use and the Association with Infections in Pediatric Patients at a Tertiary Care Oncology Hospital

2021 ◽  
Vol 10 (Supplement_1) ◽  
pp. S16-S16
Author(s):  
Jennia J Acebo ◽  
María Costta ◽  
Gisella Sánchez ◽  
Erika Villanueva ◽  
Erika Montalvo E ◽  
...  
Keyword(s):  
Cancer Patients ◽  
Complication Rate ◽  
Best Practice ◽  
Infectious Complication ◽  
Pediatric Patients ◽  
Tertiary Care ◽  
Bloodstream Infections ◽  
Complication Rates ◽  
Peripheral Venous Access ◽  
Pediatric Cancer Patients

Abstract Introduction Pediatric cancer patients merit the placement of central lines for the treatments they receive. Subcutaneous central ports (SCs) and peripherally inserted central catheters (PICCs) are the most frequently used lines. PICCs have gained popularity due to the ease of insertion, which can be invaluable in the pediatric oncology setting for administration of intravenous therapy, parenteral nutrition, and/or blood products. Since central-line-associated bloodstream infections increase the morbidity and mortality of cancer patients, as well as increase the cost generated by their treatment, active surveillance of these healthcare-associated infections is warranted. Methods This is a retrospective descriptive study of pediatric patients treated via PICCs at the Hospital SOLCA Núcleo Quito between 2009 and 2019. Results During the study period, 70 PICC lines were placed in 66 patients, totaling 1862 catheter-days. The majority of patients (75.7%) were diagnosed with leukemia or lymphoma. As of 2011, all PICCs were placed in the operating room by a surgeon. Ultrasound was used 39 times for the insertion of PICCs. Inadequate peripheral venous access was the most common indication (64.2%) for placement. Twenty-nine PICCs had complications, of which 13 were infectious complications and 16 were noninfectious. The most common infectious complication was PICC-related bloodstream infection (13), and the most frequent noninfectious complication was occlusion (10). The overall complication rate was 15.5 complications per 1000 catheter-days, and the overall infectious complication rate was 6.9 complications per 1000 catheter days. Annual complication rates fluctuated over the study period. The PICC line-associated infection rate per 1000 catheter-days was 13.1‰ in 2009, 12.4‰ in 2010, 5.0‰ in 2011, 7.9‰ in 2012, 0 in 2013, 13.4‰ in 2014, 4.8‰ in 2015, 16.2‰ in 2016, 8.2‰ in 2017, and 4.3‰ in 2018. Conclusion In general, complications related to PICC in pediatric patients at a tertiary care oncology hospital have fluctuated over the years. Our findings indicate the need for further efforts in staff education and training in the insertion, care, and maintenance of PICC lines. Best practice guidelines are also critical to reducing complications, especially occlusion and infection rates, to thereby improve patient outcomes.

Corticosteroids and immunomodulators: postoperative infectious complication risk in inflammatory bowel disease patients

2003 ◽  
Vol 125 (2) ◽  
pp. 320-327 ◽  
Author(s):  
Faten N Aberra ◽  
James D Lewis ◽  
David Hass ◽  
John L Rombeau ◽  
Benjamin Osborne ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Infectious Complication ◽  
Postoperative Infectious Complication ◽  
Complication Risk ◽  
Inflammatory Bowel

Effects of preoperative nutrition on postoperative outcomes in esophageal cancer: a systematic review and meta-analysis

2021 ◽  
Author(s):  
Yuqin Cao ◽  
Dingpei Han ◽  
Xiang Zhou ◽  
Yu Han ◽  
Yajie Zhang ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Hospital Mortality ◽  
Complication Rate ◽  
Nutritional Support ◽  
Infectious Complication ◽  
Meta Analysis ◽  
Feeding Tube ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
Preoperative Nutrition

Summary Postoperative enteral nutrition has been widely implemented in esophageal cancer, but the efficacy and safety of preoperative nutrition, particularly immune-enhancing nutrition (IEN), remain controversial. This meta-analysis aims to provide a quantitative synthesis of whether preoperative nutrition improves postoperative morbidity and mortality in patients with resectable esophageal cancer. A systematic search was conducted in Medline, Embase, Cochrane, and databases of clinical trials dated up to December 2019. Randomized controlled trials and observational studies comparing postoperative outcomes between esophageal cancer patients with and without preoperative nutritional support were included. Random-effects model was applied in the meta-analysis of primary outcomes (overall complication rate, in-hospital mortality) and secondary outcomes (infectious complication rate, anastomotic leak rate, length of postoperative hospital stay). Complications of feeding tube access and perioperative weight loss were evaluated by qualitative synthesis. Subgroup analyses were performed by stratifying immunonutrition and standard nutrition before surgery. Subgroup analysis of randomized controlled trials alone was also done. A total of 15 studies enrolling 1864 participants were included. The overall meta-analysis found that preoperative nutrition could reduce infectious complications (odds ratio [OR] = 0.51, 95% confidence interval [CI] [0.26, 0.98]; I2 = 48%) and length of hospital stay (mean difference = −2.10 day, 95% CI [−3.72, −0.47]; I2 = 78%) after esophagectomy, whereas no significant difference was revealed in the incidence of overall complications (OR = 0.76, 95% CI [0.52, 1.11]; I2 = 32%), in-hospital mortality (OR = 1.03, 95% CI [0.41, 2.61]; I2 = 12%), and anastomotic leak (OR = 1.05, 95% CI [0.69, 1.58]; I2 = 0%). Subgroup of preoperative immunonutrition showed more prominent benefits. The complication rate of feeding tube access was low (1.6–16%). In conclusion, preoperative nutrition is safe in esophageal cancer, but benefits are observed in infectious complication rate and length of stay on a limited scale. IEN holds more advantages over standard nutrition. Randomized trials in the context of nutritional support during neoadjuvant therapy are in demand.

Impact of postoperative infectious complications on adjuvant chemotherapy administration after gastrectomy for advanced gastric cancer

2020 ◽  
Author(s):  
Hironori Tsujimoto ◽  
Keita Kouzu ◽  
Hidekazu Sugasawa ◽  
Shinsuke Nomura ◽  
Nozomi Ito ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Adjuvant Chemotherapy ◽  
Infectious Complication ◽  
Univariate Analysis ◽  
Dose Intensity ◽  
Clinicopathological Characteristics ◽  
Infectious Complications ◽  
Postoperative Infectious Complication ◽  
Chemotherapy Administration ◽  
The Impact

Abstract Background The aim of this study was to investigate the impact of postoperative infectious complications on adjuvant chemotherapy administration in patients with gastric cancer. Methods A retrospective review of 308 patients who underwent curative resection for gastric cancer was performed. Patients were divided into two groups based on the presence (90 patients, 29.2%) or absence (218 patients, 70.8%) of postoperative infectious complications to analyze clinicopathological characteristics, treatment factors and survival. Results Fewer patients with postoperative infectious complication received adjuvant chemotherapy compared to those without postoperative infectious complication. The proportion of patients who started treatment within 6 weeks after surgery was significantly lower in patients with postoperative infectious complication. The treatment completion rate was significantly lower in patients with postoperative infectious complication. The number of treatment cycles and relative dose intensity was significantly lower in patients with postoperative infectious complication. In univariate analysis, only postoperative infectious complication was significantly associated with continuation of adjuvant chemotherapy. Multivariate analysis demonstrated tumor depth, nodal involvement, postoperative infectious complication and adjuvant chemotherapy were significantly associated with overall survival. Conclusion Postoperative infectious complications are significantly associated with the delay of adjuvant chemotherapy and predict adverse clinical outcome in patients with gastric cancer.

scholarly journals MICROBIOLOGICAL ANALYSIS OF BILE IN PATIENTS WITH BENIGN AND MALIGNANT BILIOPANCREATIC DISEASES AND ITS CONSEQUENCES

2016 ◽  
Vol 53 (3) ◽  
pp. 156-162 ◽  
Author(s):  
José Roberto ALVES ◽  
Rodrigo do Carmo SILVA ◽  
Sâmea Costa Pinheiro GUERRA ◽  
Tiago Tavares de FREITAS ◽  
Dyego Leandro Bezerra de SOUZA ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Cancer Patients ◽  
Infectious Complication ◽  
Infectious Complications ◽  
Microbiological Analysis ◽  
Postoperative Infectious Complication ◽  
Duodenal Papilla ◽  
Benign Diseases ◽  
Bile Samples ◽  
Microbiological Flora

ABSTRACT Background Bactibilia has several consequences to human health. Objetive Assessing the bile microbiology of patients with biliopancreatic diseases in order to identify bacteria and their possible infectious complications. Methods Retrospective study of 30 bile culture samples from patients with benign and malignant biliopancreatic diseases. The samples were assessed to set the bile microbiological flora and to search for its possible link with comorbidity, carcinogenesis and postoperative infectious complications. Results Thirty bile samples from patients at mean age ≈57.7 years, mostly female (n=18), were assessed. Bactibilia was found in 12 cases, mostly in patients with benign diseases (n=8), older than 50 years (n=23) and female (n=10). Adenocarcinoma of the duodenal papilla (n=9) and cholelithiasis (n=8) were the most common diseases. Escherichia coli (n=5) and Klebsiella sp (n=3) were predominantly found in patients with benign diseases; and Klebsiella sp (n=2) and Streptococcus sp (n=2) were prevalent in cancer patients. There were postoperative infectious complications in seven cases, five of them in bactibilia-associated patients (P=0.084). Conclusion Bactibilia was found in 12 samples and Escherichia coli and Klebsiella sp were most often identified in patients with benign diseases, as well as Streptococcus sp and Klebsiella sp in cancer patients. There was a trend of higher postoperative infectious complication incidence in patients with bactibilia.

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