Bronchogenic Cyst of the Gastric Fundus Presenting as a Gastrointestinal Stromal Tumor

2005 ◽  
Vol 15 (2) ◽  
pp. 163-165 ◽  
Author(s):  
Nicolas Melo ◽  
Martha Bishop Pitman ◽  
David W. Rattner
Keyword(s):  
Gastrointestinal Stromal Tumor ◽  
Bronchogenic Cyst ◽  
Gastric Fundus ◽  
Stromal Tumor

scholarly journals TOMOGRAPHIC FINDINGS OF GASTRIC GASTROINTESTINAL STROMAL TUMOR AND CORRELATION WITH THE MITOTIC INDEX

2013 ◽  
Vol 50 (4) ◽  
pp. 244-250 ◽  
Author(s):  
Gustavo Lemos PELANDRÉ ◽  
Maria Célia DJAHJAH ◽  
Emerson Leandro GASPARETTO ◽  
Marcelo Souto NACIF ◽  
Edson MARCHIORI ◽  
...  
Keyword(s):  
Gastrointestinal Stromal Tumor ◽  
Mitotic Index ◽  
Statistical Correlation ◽  
Gastric Fundus ◽  
The Body ◽  
Stromal Tumor ◽  
Gastric Body ◽  
Dense Area ◽  
Stromal Tumors ◽  
Mesenteric Fat

ContextGastrointestinal stromal tumors are uncommon abdominal neoplasms and can affect any portion of the gastrointestinal tract.ObjectivesDescribe the tomographic findings of the gastrointestinal stromal tumor of gastric origin, correlating it with the mitotic index.MethodsTwenty-one patients were selected within the period of January 2000 and 2008, with histopathological and immunohistochemical diagnosis of gastric gastrointestinal stromal tumors, who presented computed tomography done before the treatment. The tomographic variables analyzed were lesion topography, dimensions, contours, morphology, pattern and intensity enhancement through venous contrast, growth pattern, invasion of adjacent organs, presence of ulceration, fistula, calcifications, infiltration of mesenteric fat, lymphadenopathy and metastasis. The mitotic index was determined through optic microscopy, counting the number of mitosis figures in 50 high power fields.ResultsThe tumors were located in the body (66.7%) or gastric fundus (33.3%), with dimensions varying between 4.2 and 21.2 cm (average of 10.5 cm). The growth was predominantly extraluminal (47.6%) or intra/extra luminal (28.6%). The enhancement by venous contrast was heterogeneous in 66.7%. The statistical analysis showed that irregular morphology (P = 0.027) and infiltration of mesenteric fat (P = 0.012) presented correlation with the high mitotic index.ConclusionsIn the present study, most part of the tumors were located in the gastric body, with average size of 10.5 cm, presenting central hypo dense area, heterogeneous enhancement through contrast and predominantly extra luminal growth. Irregular morphology and infiltration of mesenteric fat present statistical correlation with high mitotic level.

scholarly journals Hybrid NOTES: Complete Endoscopic Resection of the Gastric Wall Assisted by Laparoscopy in a Gastric Fundus Gastrointestinal Stromal Tumor

2018 ◽  
Vol 26 (3) ◽  
pp. 215-217
Author(s):  
João Fernandes ◽  
Diogo Libânio ◽  
Sílvia Giestas ◽  
Tarcísio Araújo ◽  
José Ramada ◽  
...  
Keyword(s):  
Gastrointestinal Stromal Tumor ◽  
Endoscopic Resection ◽  
Gastric Wall ◽  
Gastric Fundus ◽  
Stromal Tumor ◽  
Hybrid Notes

scholarly journals Gastric carcinoma with a gastrointestinal stromal tumor

2018 ◽  
Vol 34 ◽  
pp. 15-19
Author(s):  
Sen Liu ◽  
Hongyu Liu ◽  
Yunlong Dong ◽  
Fengbiao Wang ◽  
Huijuan Wang ◽  
...  
Keyword(s):  
Gastric Carcinoma ◽  
Gastrointestinal Stromal Tumor ◽  
High Throughput ◽  
High Throughput Sequencing ◽  
Neuroendocrine Differentiation ◽  
Tp53 Gene ◽  
Gastric Fundus ◽  
Gastric Antrum ◽  
Stromal Tumor ◽  
Sequencing Analysis

Gastric carcinoma (GC) with gastrointestinal stromal tumor (GIST) is encountered very rarely in the clinic, and few cases have been reported in the literature. Here, we present a case involving a 72-year-old man who was diagnosed with gastric antrum adenocarcinoma accompanied by neuroendocrine differentiation and a GIST in the fundus, according to a preoperative examination and postoperative pathology. The patient then underwent a distal radical gastrectomy and GIST resection. After the operation, the patient was administered combined chemo-radiotherapy and subsequently underwent a 9-month follow-up examination. The gene mutations involved in this case were explored via high-throughput sequencing. The high-throughput gene mutation analysis indicated an exon5 mutation in the TP53 gene and copy number amplification of FGF19, CCND1, and FGFR2 in the gastric antrum adenocarcinoma. A gene sequencing analysis of the gastric fundus stromal tumor demonstrated an exon11 non-frame shift deletion mutation in the KIT gene. These findings suggested that this patient’s cancer might be sensitive to AZD1775 (a TP53-targeted drug) or targeted drugs such as FGF19, CCND1 and FGFR2, and should be sensitive to imatinib.

scholarly journals Gastric fundus splenosis with hemangioma masquerading as a gastrointestinal stromal tumor in a patient with schistosomiasis and cirrhosis who underwent splenectomy

Medicine ◽  
2018 ◽  
Vol 97 (27) ◽  
pp. e11461 ◽  
Author(s):  
Bing Guan ◽  
Xiao-Hong Li ◽  
Liang Wang ◽  
Min Zhou ◽  
Zhi-Wu Dong ◽  
...  
Keyword(s):  
Gastrointestinal Stromal Tumor ◽  
Gastric Fundus ◽  
Stromal Tumor

scholarly journals Traction with snare during endoscopic submucosal dissection of a gastrointestinal stromal tumor in the gastric fundus

Endoscopy ◽  
2016 ◽  
Vol 48 (S 01) ◽  
pp. E183-E185
Author(s):  
Mu Lü ◽  
Kuang-I Fu ◽  
Zhong Wang ◽  
Yong Liu ◽  
Hong Xia ◽  
...  
Keyword(s):  
Endoscopic Submucosal Dissection ◽  
Gastrointestinal Stromal Tumor ◽  
Gastric Fundus ◽  
Stromal Tumor ◽  
Submucosal Dissection

scholarly journals Accessory spleen originating from the intrinsic muscularis of the stomach misdiagnosed as gastrointestinal stromal tumor: a case report

2020 ◽  
Vol 48 (8) ◽  
pp. 030006052093530
Author(s):  
Jing Zhang ◽  
Jin-Wei Zhong ◽  
Guang-Rong Lu ◽  
Yu-Hui Zhou ◽  
Zhan-Xiong Xue ◽  
...  
Keyword(s):  
Gastrointestinal Stromal Tumor ◽  
Clinical Symptoms ◽  
Accessory Spleen ◽  
Gastric Fundus ◽  
Stromal Tumor ◽  
Pathological Examination ◽  
Gastric Body ◽  
Spleen Tissue ◽  
Muscular Layer ◽  
Gastric Submucosal Tumors

A 34-year-old man presented to our hospital with a 2-month history of repeated dull upper abdominal pain. Gastroscopy and endoscopic ultrasonography indicated a hemispherical mass at the junction of the greater curvature and the gastric fundus, with hypoechogenicity originating from the intrinsic muscular layer. He was diagnosed with a gastric body submucosal lesion and gastrointestinal stromal tumor, and underwent endoscopic full-thickness resection. However, postoperative pathological examination of the mass unexpectedly revealed heterotopic spleen tissue (accessory spleen). Intragastric ectopic spleen tissue originating from the intrinsic muscular layer of the stomach is a rare clinical condition, with no specific clinical symptoms. This finding is of great clinical significance for the identification of gastric submucosal tumors.

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