Disease Burden and Health-Related Quality of Life Among Women and Men with Spondyloarthritis: An Exploratory Analysis of a Population-Based Sample

2021 ◽  
Author(s):  
Divya Shridharmurthy ◽  
Danni Zhao ◽  
Kate L. Lapane ◽  
Jonggyu Baek ◽  
Jonathan Kay ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Disease Burden ◽  
Population Based ◽  
Exploratory Analysis ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

Epidemiology and Disease Burden of Androgenetic Alopecia in Chinese Adolescents: a Population-based Study (Preprint)

2021 ◽  
Author(s):  
Fanping He ◽  
Minxue Shen ◽  
Zhixiang Zhao ◽  
Yicong Liu ◽  
Shuping Zhang ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Psychological Health ◽  
Disease Burden ◽  
Population Based ◽  
Chinese Adolescents ◽  
Androgenetic Alopecia ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related

BACKGROUND Androgenetic alopecia (AGA) is the most common type of hair loss and can onset at any age. It was reported to have a significant effect on health-related quality of life and psychological health. Reported prevalence rate is associated with multiple factors. However, these prevalence and disease burden in adolescents has not been explored. OBJECTIVE To evaluate the epidemiology and disease burden of AGA in Chinese adolescents. METHODS This population-based cross-sectional survey was carried out among 9227 freshmen of two comprehensive universities in two cities of China from September to October 2018. Dermatological examination was performed by certified dermatologists. Questionnaires covering basic issues, surrounding demographic information, history of diseases, etc. were completed online. Disease burden of AGA, including health-related quality of life, symptoms of anxiety and depression, and quality of sleep, was measured by EQ-5D-3L, PHQ-2, GAD-2 and PSQI. Meanwhile, 45 adolescents AGA patients visiting Xiangya hospital were enrolled as clinic AGA group for comparison of disease burden. RESULTS The prevalence of AGA in Chinese adolescents was 5.3/1000. Male was significantly associated with higher prevalence of AGA (7.9/1000, P<0.01). Female was associated with lower risk of AGA (OR=0.29, P=0.002). There was no significant association between BMI and AGA, nor predilection in different nationality. Annual household income or parental highest educational level exerted no influence on the prevalence of AGA. Rosacea (OR=3.22, P=0.019) was significantly associated with higher prevalence of AGA while acne seemed no association. The scores of EQ-5D, GAD-2, PHQ-2 and PSQI were not significantly different between students with and without AGA. However, the GAD-2, PHQ-2 and PSQI of clinic adolescent AGA patients were significantly higher than college patients. CONCLUSIONS The onset of AGA in Chinese college students differs between genders and was significantly associated with rosacea. Clinic AGA patients suffered from significant heavier disease burden compared to college AGA patients.

scholarly journals The impact of multimorbidity patterns on health-related quality of life in the general population: results of the Belgian Health Interview Survey

2021 ◽  
Author(s):  
Lisa Van Wilder ◽  
Brecht Devleesschauwer ◽  
Els Clays ◽  
Stefanie De Buyser ◽  
Johan Van der Heyden ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Chronic Diseases ◽  
Disease Burden ◽  
Health Related Quality ◽  
Health Interview Survey ◽  
Related Quality ◽  
Health Related ◽  
Interview Survey ◽  
The Impact

Abstract Background Chronic diseases and multimorbidity are a major cause of disease burden—for patients, caregivers, and society. Little is known however about potential interaction effects between specific disease combinations. Besides an additive effect, the presence of multiple conditions could also act synergistically or antagonistically regarding the impact on patients’ health-related quality of life (HRQoL). The aim was to estimate the impact of coexisting chronic diseases on HRQoL of the adult general Belgian population. Methods The Belgian Health Interview Survey 2018 provided data on self-reported chronic conditions and HRQoL (EQ-5D-5L) for a nationally representative sample. Linear mixed models were used to analyze two-way and three-way interactions of disease combinations on HRQoL. Results Multimorbidity had a prevalence of 46.7% (≥ 2 conditions) and 29.7% (≥ 3 conditions). HRQoL decreased considerably with the presence of multiple chronic diseases. 14 out of 41 dyad combinations and 5 out of 13 triad combinations showed significant interactions, with a dominant presence of negative/synergistic effects. Positive/antagonistic effects were found in more subjective chronic diseases such as depression and chronic fatigue. Conditions appearing the most frequently in significant disease pair interactions were dorsopathies, respiratory diseases, and arthropathies. Conclusions Diverse multimorbidity patterns, both dyads and triads, were synergistically or antagonistically associated with lower HRQoL. Tackling the burden of multimorbidity is needed, especially because most disease combinations affect each other synergistically, resulting in a greater reduction in HRQoL. Further knowledge about those multimorbidity patterns with a greater impact on HRQoL is needed to better understand disease burden beyond mortality and morbidity data.

The predictive validity of health-related quality of life measures: mortality in a longitudinal population-based study

2007 ◽  
Vol 16 (9) ◽  
pp. 1539-1546 ◽  
Author(s):  
Mark S. Kaplan ◽  
Jean-Marie Berthelot ◽  
David Feeny ◽  
Bentson H. McFarland ◽  
Saeeda Khan ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Predictive Validity ◽  
Population Based ◽  
Health Related Quality ◽  
Population Based Study ◽  
Quality Of Life Measures ◽  
Related Quality ◽  
Health Related

scholarly journals Impact of long-COVID on health-related quality of life in Japanese COVID-19 patients

2021 ◽  
Author(s):  
Shinya Tsuzuki ◽  
Yusuke Miyazato ◽  
Mari Terada ◽  
Shinichiro Morioka ◽  
Norio Ohmagari ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Disease Burden ◽  
Self Report ◽  
Health Related Quality ◽  
Cross Sectional ◽  
Long Duration ◽  
Related Quality ◽  
Health Related ◽  
Basic Characteristics

AbstractBackgroundThe empirical basis for a quantitative assessment of the disease burden imposed by long-COVID is currently scant. We aimed to assess the disease burden caused by long-COVID in Japan.MethodsWe conducted a cross sectional self-report questionnaire survey. The questionnaire was mailed to 530 eligible patients, who were recovered from acute COVID-19 in April 2021. Answers were classified into two groups; participants who have no symptom and those who have any ongoing symptoms that lasted longer than four weeks at the time of the survey. We compared health-related quality of life scores estimated by the EQ-5D-3L questionnaire between these two groups after adjusting basic characteristics of the participants by propensity score matching.Results349 participants reported no symptoms and 108 reported any symptoms at the time of the survey. The participants who reported any symptoms showed a lower value on a Visual Analogue Scale (median 70 [IQR 60-80]) and on the EQ-5D-3L (median 0.81 [IQR 0.77-1.0]) than those reporting no symptoms (median 85 [IQR 75-90] and 1.0 [IQR 1.0-1.0], respectively). After adjusting for background characteristics, these trends did not change substantially (Visual Analog Scale: median 70 [IQR 60-80] vs 80 [IQR 77-90], EQ-5D-3L: median 0.81 [IQR 0.76-1.0] vs 1.0 [IQR 1.0-1.0]).ConclusionsDue to their long duration, long-COVID symptoms represent a substantial disease burden expressed in impact on health-related quality of life.Trial registrationNot applicable.

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