Withdrawal of Invasive Home Mechanical Ventilation in Patients with Advanced Amyotrophic Lateral Sclerosis: Ten Years of Danish Experience

2012 ◽  
Vol 15 (2) ◽  
pp. 205-209 ◽  
Author(s):  
Pia Sander Dreyer ◽  
Michael Felding ◽  
Charlotte Sønderskov Klitnæs ◽  
Charlotte Kirkegård Lorenzen
Keyword(s):  
Mechanical Ventilation ◽  
Amyotrophic Lateral Sclerosis ◽  
Home Mechanical Ventilation ◽  
Danish Experience ◽  
Lateral Sclerosis

Home Mechanical Ventilation in Amyotrophic Lateral Sclerosis Patients Is Not Always a Problem

CHEST Journal ◽  
2000 ◽  
Vol 117 (3) ◽  
pp. 924 ◽  
Author(s):  
Emilio Servera ◽  
Elia Gómez-Merino ◽  
Diego Pérez ◽  
Julio Marín
Keyword(s):  
Mechanical Ventilation ◽  
Amyotrophic Lateral Sclerosis ◽  
Home Mechanical Ventilation ◽  
Lateral Sclerosis

Decision-making in the respiratory care of amyotrophic lateral sclerosis: should home mechanical ventilation be used?

1993 ◽  
Vol 7 (4_suppl) ◽  
pp. 49-64 ◽  
Author(s):  
Edward Anthony Oppenheimer
Keyword(s):  
Decision Making ◽  
Mechanical Ventilation ◽  
Amyotrophic Lateral Sclerosis ◽  
Respiratory Function ◽  
Ventilatory Support ◽  
Respiratory Care ◽  
Home Mechanical Ventilation ◽  
Lateral Sclerosis ◽  
At Home

As respiratory function starts to deteriorate in those with amyotrophic lateral sclerosis, one of the principal questions that has to be answered is whether it is appropriate to provide ventilatory support. Although expensive, it is perfectly feasible to provide this at home, and this article examines many of the issues surrounding home mechanical ventilation.

Survival in Amyotrophic Lateral Sclerosis With Home Mechanical Ventilation

CHEST Journal ◽  
2005 ◽  
Vol 127 (6) ◽  
pp. 2132-2138 ◽  
Author(s):  
Eva Farrero ◽  
Enric Prats ◽  
Mónica Povedano ◽  
J. Antonio Martinez-Matos ◽  
Frederic Manresa ◽  
...  
Keyword(s):  
Mechanical Ventilation ◽  
Amyotrophic Lateral Sclerosis ◽  
Home Mechanical Ventilation ◽  
Lateral Sclerosis

scholarly journals Cost–Utility Analysis of Home Mechanical Ventilation in Patients with Amyotrophic Lateral Sclerosis

Healthcare ◽  
2021 ◽  
Vol 9 (2) ◽  
pp. 142
Author(s):  
Ondřej Gajdoš ◽  
Martin Rožánek ◽  
Gleb Donin ◽  
Vojtěch Kamenský
Keyword(s):  
Mechanical Ventilation ◽  
Amyotrophic Lateral Sclerosis ◽  
Cost Utility ◽  
Cost Utility Analysis ◽  
Model Parameters ◽  
Utility Analysis ◽  
Home Mechanical Ventilation ◽  
Life Years ◽  
Lateral Sclerosis ◽  
Quality Adjusted Life

Amyotrophic lateral sclerosis is a disease with rapid progression. The use of mechanical ventilation helps to manage symptoms and delays death. Use in a home environment could reduce costs and increase quality of life. The aim of this study is a cost–utility analysis of home mechanical ventilation in adult patients with amyotrophic lateral sclerosis from the perspective of healthcare payers in the Czech Republic. The study evaluates home mechanical ventilation (HMV) and mechanical ventilation (MV) in a healthcare facility. A Markov model was compiled for evaluation in a timeframe of 10 years. Model parameters were obtained from the literature and opinions of experts from companies dealing with home care and home mechanical ventilation. The cost–utility analysis was carried out at the end of the study and results are presented in incremental cost–utility ratio (ICUR) using quality-adjusted life-years. Uncertainty was assessed by one-way sensitivity analysis and scenario analysis. The cumulative costs of HMV are CZK 1,877,076 and the cumulative costs of the MV are CZK 7,386,629. The cumulative utilities of HMV are 12.57 quality-adjusted life year (QALY) and the cumulative utilities of MV are 11.32 QALY. The ICUR value is CZK-4,403,259. The results of this study suggest that HMV is cost effective.

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