Senescent Retinal Pigment Epithelial Cells Are More Sensitive to Vascular Endothelial Growth Factor: Implications for “Wet” Age-Related Macular Degeneration

Michael R. Kozlowski

doi:10.1089/jop.2014.0071

Senescent Retinal Pigment Epithelial Cells Are More Sensitive to Vascular Endothelial Growth Factor: Implications for “Wet” Age-Related Macular Degeneration

Journal of Ocular Pharmacology and Therapeutics ◽

10.1089/jop.2014.0071 ◽

2015 ◽

Vol 31 (2) ◽

pp. 87-92 ◽

Cited By ~ 2

Author(s):

Michael R. Kozlowski

Keyword(s):

Vascular Endothelial Growth Factor ◽

Retinal Pigment Epithelial ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Age Related Macular Degeneration ◽

Vascular Endothelial ◽

Pigment Epithelial ◽

Age Related ◽

Endothelial Growth Factor ◽

Pigment Epithelial Cells

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Nanoparticle formulation enhances the delivery and activity of a vascular endothelial growth factor antisense oligonucleotide in human retinal pigment epithelial cells

Journal of Pharmacy and Pharmacology ◽

10.1211/0022357021701 ◽

2003 ◽

Vol 55 (9) ◽

pp. 1199-1206 ◽

Cited By ~ 34

Author(s):

Jithan V. Aukunuru ◽

Surya P. Ayalasomayajula ◽

Uday B. Kompella

Keyword(s):

Vascular Endothelial Growth Factor ◽

Antisense Oligonucleotide ◽

Retinal Pigment Epithelial ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Vascular Endothelial ◽

Pigment Epithelial ◽

Nanoparticle Formulation ◽

Endothelial Growth Factor ◽

Pigment Epithelial Cells

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Hypothermia reduces secretion of vascular endothelial growth factor by cultured retinal pigment epithelial cells

British Journal of Ophthalmology ◽

10.1136/bjo.2009.168864 ◽

2010 ◽

Vol 94 (12) ◽

pp. 1678-1683 ◽

Cited By ~ 17

Author(s):

M. Coassin ◽

K. G. Duncan ◽

K. R. Bailey ◽

A. Singh ◽

D. M. Schwartz

Keyword(s):

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Epithelial Cells ◽

Retinal Pigment Epithelial ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Vascular Endothelial ◽

Pigment Epithelial ◽

Endothelial Growth Factor ◽

Pigment Epithelial Cells

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Induction of vascular endothelial growth factor by 4-hydroxynonenal and its prevention by glutathione precursors in retinal pigment epithelial cells

European Journal of Pharmacology ◽

10.1016/s0014-2999(02)02043-5 ◽

2002 ◽

Vol 449 (3) ◽

pp. 213-220 ◽

Cited By ~ 41

Author(s):

Surya P Ayalasomayajula ◽

Uday B Kompella

Keyword(s):

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Epithelial Cells ◽

Retinal Pigment Epithelial ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Vascular Endothelial ◽

Pigment Epithelial ◽

Endothelial Growth Factor ◽

Pigment Epithelial Cells

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Thiol regulation of vascular endothelial growth factor-A and its receptors in human retinal pigment epithelial cells

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2006.06.021 ◽

2006 ◽

Vol 346 (4) ◽

pp. 1200-1206 ◽

Cited By ~ 19

Author(s):

Parameswaran G. Sreekumar ◽

Ram Kannan ◽

Aruni T. de Silva ◽

Richard Burton ◽

Stephen J. Ryan ◽

...

Keyword(s):

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Epithelial Cells ◽

Retinal Pigment Epithelial ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Vascular Endothelial ◽

Pigment Epithelial ◽

Endothelial Growth Factor ◽

Pigment Epithelial Cells

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Hypoxic Induction of Vascular Endothelial Growth Factor (VEGF) and HIF-1 Protein in Retinal Pigment Epithelial Cells

Pediatric Research ◽

10.1203/00006450-199904020-01243 ◽

1999 ◽

Vol 45 (4, Part 2 of 2) ◽

pp. 209A-209A

Author(s):

Ashima Madan ◽

Sushama Varma ◽

Harvey J Cohen

Keyword(s):

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Retinal Pigment Epithelial ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Vascular Endothelial ◽

Hypoxic Induction ◽

Pigment Epithelial ◽

Endothelial Growth Factor ◽

Pigment Epithelial Cells

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Hyperthermia-induced upregulation of vascular endothelial growth factor in retinal pigment epithelial cells is regulated by mitogen-activated protein kinases

Graefe s Archive for Clinical and Experimental Ophthalmology ◽

10.1007/s00417-014-2750-z ◽

2014 ◽

Vol 252 (11) ◽

pp. 1737-1745 ◽

Cited By ~ 8

Author(s):

Hendrik Faby ◽

Jost Hillenkamp ◽

Johann Roider ◽

Alexa Klettner

Keyword(s):

Vascular Endothelial Growth Factor ◽

Retinal Pigment Epithelial ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Vascular Endothelial ◽

Mitogen Activated Protein Kinases ◽

Pigment Epithelial ◽

Mitogen Activated Protein ◽

Endothelial Growth Factor ◽

Pigment Epithelial Cells

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Methylglyoxal-induced imbalance in the ratio of vascular endothelial growth factor to angiopoietin 2 secreted by retinal pigment epithelial cells leads to endothelial dysfunction

Experimental Physiology ◽

10.1113/expphysiol.2010.053561 ◽

2010 ◽

Vol 95 (9) ◽

pp. 955-970 ◽

Cited By ~ 54

Author(s):

C. F. Bento ◽

R. Fernandes ◽

P. Matafome ◽

C. Sena ◽

R. Seiça ◽

...

Keyword(s):

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Retinal Pigment Epithelial ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Vascular Endothelial ◽

Pigment Epithelial ◽

Angiopoietin 2 ◽

Endothelial Growth Factor ◽

Pigment Epithelial Cells

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Transdifferentiated Retinal Pigment Epithelial Cells are Immunoreactive for Vascular Endothelial Growth Factor in Surgically Excised AgeRelated Macular Degeneration-Related Choroidal Neovascular Membranes.

Retina ◽

10.1097/00006982-199805000-00035 ◽

1998 ◽

Vol 18 (5) ◽

pp. 493 ◽

Cited By ~ 1

Author(s):

P F Lopez ◽

B D Sippy ◽

H M Lambert ◽

A B Thach ◽

D R Hinton

Keyword(s):

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Macular Degeneration ◽

Retinal Pigment Epithelial ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Vascular Endothelial ◽

Pigment Epithelial ◽

Endothelial Growth Factor ◽

Pigment Epithelial Cells

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Inhibition of Vascular Endothelial Growth Factor Synthesis in Human Retinal Pigment Epithelial Cells by Pazopanib

Journal of Modern Medicinal Chemistry ◽

10.12970/2308-8044.2015.03.02.1 ◽

2015 ◽

Vol 3 (2) ◽

pp. 44-48

Author(s):

Monte Monte ◽

◽

Piyush Kothary ◽

Neilesh Parikh

Keyword(s):

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Epithelial Cells ◽

Retinal Pigment Epithelial ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Vascular Endothelial ◽

Pigment Epithelial ◽

Endothelial Growth Factor ◽

Pigment Epithelial Cells

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Synthesis and Secretion of Vascular Permeability Factor/Vascular Endothelial Growth Factor by Human Retinal Pigment Epithelial Cells

Biochemical and Biophysical Research Communications ◽

10.1006/bbrc.1993.1671 ◽

1993 ◽

Vol 193 (2) ◽

pp. 631-638 ◽

Cited By ~ 242

Author(s):

A.P. Adamis ◽

D.T. Shima ◽

K.T. Yeo ◽

T.K. Yeo ◽

L.F. Brown ◽

...

Keyword(s):

Vascular Endothelial Growth Factor ◽

Growth Factor ◽

Retinal Pigment Epithelial ◽

Retinal Pigment ◽

Retinal Pigment Epithelial Cells ◽

Vascular Endothelial ◽

Vascular Permeability Factor ◽

Pigment Epithelial ◽

Endothelial Growth Factor ◽

Pigment Epithelial Cells

Download Full-text