Comparison of 24-Hour Intraocular Pressure Reduction Obtained with Brinzolamide/Timolol or Brimonidine/Timolol Fixed-Combination Adjunctive to Travoprost Therapy

2013 ◽  
Vol 29 (7) ◽  
pp. 652-657 ◽  
Author(s):  
Anastasios G. P. Konstas ◽  
Gábor Holló ◽  
Anna-Bettina Haidich ◽  
Dimitrios G. Mikropoulos ◽  
Theodoros Giannopoulos ◽  
...  
2010 ◽  
Vol 10 (1) ◽  
Author(s):  
Eric Sellem ◽  
Jean François Rouland ◽  
Christophe Baudouin ◽  
Alain Bron ◽  
Philippe Denis ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Ryoko Igarashi ◽  
Tetsuya Togano ◽  
Yuta Sakaue ◽  
Takaiko Yoshino ◽  
Jun Ueda ◽  
...  

Purpose. To evaluate the effect on intraocular pressure (IOP) of switching from latanoprost and travoprost monotherapy to timolol fixed combinations in Japanese patients with normal-tension glaucoma (NTG).Methods. 27 NTG patients (54 eyes) were compared IOP, superficial punctuate keratitis (SPK) scores, and conjunctival injection scores in eyes treated with prostaglandin (PG) or PG analog/beta-blocker (PG/b) fixed-combination 6 months after the change in therapy.Results. The mean baseline intraocular pressure was17.4±1.59 mmHg in eyes receiving PG therapy only and17.4±1.69 mmHg in eyes switched to PG/b. Switching to fixed combination therapy from PG monotherapy, the mean IOP was13.1±1.79 mmHg(P<0.001)  (-24.71% reduction from baseline) at 6 months. The mean conjunctival injection score was 0.69 for eyes on PG monotherapy and 0.56 for eyes on fixed combination therapy(P=0.028). The mean SPK scores were 0.46 and 0.53. This difference was not statistically significant(P=0.463).Conclusions. Switching from PG monotherapy to PG/b fixed combination therapy for NTG resulted in a greater intraocular pressure reduction than PG alone without increasing the number of instillations.


Ophthalmology ◽  
2010 ◽  
Vol 117 (11) ◽  
pp. 2061-2066 ◽  
Author(s):  
Felipe A. Medeiros ◽  
Luciana M. Alencar ◽  
Pamela A. Sample ◽  
Linda M. Zangwill ◽  
Remo Susanna Jr. ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document