The Protective Effects of Green Tea Polyphenols: Lipid Profile, Inflammation, and Antioxidant Capacity in Rats Fed an Atherogenic Diet and Dextran Sodium Sulfate

2012 ◽  
Vol 15 (8) ◽  
pp. 726-732 ◽  
Author(s):  
Julie Bornhoeft ◽  
Debra Castaneda ◽  
Tricia Nemoseck ◽  
Piwen Wang ◽  
Susanne M. Henning ◽  
...  
Keyword(s):  
Antioxidant Capacity ◽  
Lipid Profile ◽  
Green Tea ◽  
Sodium Sulfate ◽  
Atherogenic Diet ◽  
Dextran Sodium Sulfate ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols ◽  
Protective Effects

Low and Medium but Not High Doses of Green Tea Polyphenols Ameliorated Dextran Sodium Sulfate-Induced Hepatotoxicity and Nephrotoxicity

2013 ◽  
Vol 77 (6) ◽  
pp. 1223-1228 ◽  
Author(s):  
Hirofumi INOUE ◽  
Mari MAEDA-YAMAMOTO ◽  
Atsushi NESUMI ◽  
Takuji TANAKA ◽  
Akira MURAKAMI
Keyword(s):  
Green Tea ◽  
Sodium Sulfate ◽  
Dextran Sodium Sulfate ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols ◽  
High Doses

Protective effects of green tea polyphenols on cognitive impairments induced by psychological stress in rats

2009 ◽  
Vol 202 (1) ◽  
pp. 71-76 ◽  
Author(s):  
Wei-Qiang Chen ◽  
Xiao-Ling Zhao ◽  
Yue Hou ◽  
Shu-Tian Li ◽  
Yan Hong ◽  
...  
Keyword(s):  
Psychological Stress ◽  
Green Tea ◽  
Cognitive Impairments ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols ◽  
Protective Effects

Molecular mechanisms of green tea polyphenols with protective effects against skin photoaging

2015 ◽  
Vol 57 (8) ◽  
pp. 1631-1637 ◽  
Author(s):  
Eunmiri Roh ◽  
Jong-Eun Kim ◽  
Jung Yeon Kwon ◽  
Jun Seong Park ◽  
Ann M. Bode ◽  
...  
Keyword(s):  
Green Tea ◽  
Molecular Mechanisms ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols ◽  
Protective Effects ◽  
Skin Photoaging

Protective Effects of Green Tea Polyphenols in the 6-OHDA Rat Model of Parkinson’s Disease Through Inhibition of ROS-NO Pathway

2007 ◽  
Vol 62 (12) ◽  
pp. 1353-1362 ◽  
Author(s):  
Shuhong Guo ◽  
Jingqi Yan ◽  
Tangbin Yang ◽  
Xianqiang Yang ◽  
Erwan Bezard ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Green Tea ◽  
Rat Model ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols ◽  
Protective Effects

scholarly journals Green tea polyphenols protect PC12 cells against H2O2-induced damages by upregulating lncRNA MALAT1

2019 ◽  
Vol 33 ◽  
pp. 205873841987262 ◽  
Author(s):  
Shuheng Liu ◽  
Guisheng Yu ◽  
Guohua Song ◽  
Qingguo Zhang
Keyword(s):  
Pc12 Cells ◽  
Green Tea ◽  
Caspase 3 ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols ◽  
Cell Counting ◽  
Signal Pathways ◽  
Protective Effects ◽  
Oxidative Damages ◽  
Cord Injury

It is of significance to alleviate oxidative damages for the treatment of spinal cord injury (SCI). Studies have ascertained that green tea polyphenols (GTPs) exert protective activities against oxidative damages. In this study, we aimed to investigate the protective effects of GTP against H2O2-caused injuries in PC12 cells as well as the molecular underpinnings associated with long non-coding RNA metastasis-associated lung adenocarcinoma transcript 1 (MALAT1). PC12 cells were preincubated with GTP prior to H2O2 stimulation. Furthermore, MALAT1-deficient PC12 cells were constructed by transfection and identified by quantitative real-time polymerase chain reaction (qRT-PCR) assay. Next, viability and apoptosis were detected by cell counting kit-8 and flow cytometry, respectively. Meanwhile, Western blot assay was carried out to monitor the expression alteration of proteins associated with apoptosis (Bcl-2, Bax, pro-Caspase-3/9, and cleaved Caspase-3/9) and autophagy (microtubule-associated protein 1 light chain 3 (LC3)-II, LC3-I, Beclin-1, and p62). Moreover, we examined the expression of β-catenin and dissected the phosphorylation of phosphatidylinositol 3′-kinase (PI3K) and protein kinase B (AKT). We found that H2O2 decreased the viability of PC12 cells while initiated apoptosis and autophagy processes. GTP-preincubated PC12 cells maintained the viability and resisted the apoptosis and autophagy induced by H2O2. Pointedly, GTP-pretreated PC12 cells showed an increase in MALAT1 after H2O2 stimulation. Of note, the protective effects of GTP were buffered in MALAT1-deficient cells in response to H2O2. The expression of β-catenin and phosphorylation of PI3K and AKT were upregulated by GTP, while MALAT1 knockdown led to opposite results. To sum up, GTP protected PC12 cells from H2O2-induced damages by the upregulation of MALAT1. This process might be through activating Wnt/β-catenin and PI3K/AKT signal pathways.

Metabonomics study of the protective effects of green tea polyphenols on aging rats induced by d-galactose

2011 ◽  
Vol 55 (5) ◽  
pp. 1067-1074 ◽  
Author(s):  
Chunwang Fu ◽  
Tiejie Wang ◽  
Yang Wang ◽  
Xiaohui Chen ◽  
Jian Jiao ◽  
...  
Keyword(s):  
Green Tea ◽  
Tea Polyphenols ◽  
Green Tea Polyphenols ◽  
Protective Effects ◽  
Aging Rats
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