Lamivudine and IFN-βSequential Therapy in HBe Antigen-Positive Patients with Chronic Hepatitis B Virus Genotype C Infection

2007 ◽  
Vol 27 (3) ◽  
pp. 201-208 ◽  
Author(s):  
Masaru Enomoto ◽  
Akihiro Tamori ◽  
Madoka Toyama Kohmoto ◽  
Takehiro Hayashi ◽  
Hisato Jomura ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Virus Genotype ◽  
Hbe Antigen ◽  
Chronic Hepatitis B Virus ◽  
B Virus ◽  
Genotype C

Influence of delta virus infection on the virologic status in Egyptian patients with chronic hepatitis B virus genotype D

2015 ◽  
Vol 88 (5) ◽  
pp. 837-842 ◽  
Author(s):  
Rabab Fouad ◽  
Mahmoud Abdo ◽  
Hadeel Gamal Eldeen ◽  
Dina Sabry ◽  
Mira Atef ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis B Virus ◽  
Virus Infection ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Virus Genotype ◽  
Chronic Hepatitis B Virus ◽  
B Virus ◽  
Egyptian Patients ◽  
Delta Virus

scholarly journals Towards Genotype-Specific Care for Chronic Hepatitis B: The First 6 Years Follow Up From the CHARM Cohort Study

2019 ◽  
Vol 6 (11) ◽  
Author(s):  
Jane Davies ◽  
Emma L Smith ◽  
Margaret Littlejohn ◽  
Rosalind Edwards ◽  
Vitina Sozzi ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis B Virus ◽  
Natural History ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Indigenous Australians ◽  
Virus Genotype ◽  
Chronic Hepatitis B Virus ◽  
B Virus

Abstract Objective There is increasing evidence to suggest that, among those with chronic hepatitis B virus infection, the natural history and rate of progression to cirrhosis and hepatocellular carcinoma is influenced by hepatitis B virus genotype. The unique hepatitis B virus genotype C4 circulates among Indigenous Australians. The aim of this work is to describe the process of establishing this cohort and review the first 6 years of available data in an effort to understand the real-world clinical care and natural history of this subgenotype. Method We followed a longitudinal cohort of Indigenous Australians from the Northern Territory of Australia with established subgenotype C4 infections. We assigned phases of disease according to Gastroenterological Society of Australia and Asian Pacific Association for the Study of the Liver criteria using clinical and laboratory information that had been collected for clinical management. Results Of 193 patients followed over a median of 38 months, 58 (30%) individuals transitioned from 1 disease phase to another, 10 (5%) cleared hepatitis B e antigen, and 6 cleared hepatitis B surface antigen (3%). In this relatively young cohort (median age 40.3 years), 26 (13%) had cirrhosis by the end of the follow up period, with the majority of these being in the immune control phase of disease. Conclusions In this cohort of hepatitis B subgenotype C4 patients, we report an aggressive and dynamic clinical phenotype. High rates of cirrhosis at a young age appear to occur in the early phases of disease.

scholarly journals Hepatitis B core-related antigen kinetics in chronic hepatitis B virus genotype D-infected patients treated with nucleos(t)ide analogues or pegylated-interferon-α

2016 ◽  
Vol 47 (8) ◽  
pp. 747-754 ◽  
Author(s):  
Gian Paolo Caviglia ◽  
Maria Lorena Abate ◽  
Daniele Noviello ◽  
Antonella Olivero ◽  
Chiara Rosso ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Pegylated Interferon ◽  
Interferon Α ◽  
Virus Genotype ◽  
Chronic Hepatitis B Virus ◽  
B Virus

Subgenotypes of hepatitis B virus genotype C do not correlate with disease progression of chronic hepatitis B in Taiwan

2007 ◽  
Vol 27 (7) ◽  
pp. 983-988 ◽  
Author(s):  
Tai-Chung Tseng ◽  
Chun-Jen Liu ◽  
Pei-Jer Chen ◽  
Ming-Yang Lai ◽  
Chih-Lin Lin ◽  
...  
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Disease Progression ◽  
Chronic Hepatitis B ◽  
Virus Genotype ◽  
B Virus ◽  
Genotype C
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