Recent Advances in Predictive Understanding of Respiratory Tract Deposition

2008 ◽  
Vol 0 (0) ◽  
pp. 080225123426385-18 ◽  
Author(s):  
Warren H. Finlay ◽  
Andrew R. Martin
Keyword(s):  
Respiratory Tract ◽  
Recent Advances ◽  
Predictive Understanding

scholarly journals Hemiplegia laryngis in sport horses: recent advances and status today

2019 ◽  
Vol 5 (2) ◽  
pp. 176-180
Author(s):  
E. Ulybina ◽  
A. Tsvetkova ◽  
D. Lukina
Keyword(s):  
Minimally Invasive ◽  
Respiratory Tract ◽  
Genetic Susceptibility ◽  
Research Data ◽  
Upper Respiratory Tract ◽  
Recent Advances ◽  
Disease Aetiology ◽  
Upper Respiratory ◽  
Athletic Career

Laryngeal hemiplegia today is one of the most common pathologies of the upper respiratory tract of large breed sports horses and can greatly affect the performance of an animal and its athletic career. This article reviews the latest research data on the nature of this disease, aetiology, pathogenesis and classification, the genetic susceptibility of large horses to this pathology, the method of minimally invasive diagnosis, and the method of treatment of this disease, which is currently the most effective.

scholarly journals Recent advances in understanding rhinovirus immunity

F1000Research ◽  
2018 ◽  
Vol 7 ◽  
pp. 1537 ◽  
Author(s):  
Spyridon Makris ◽  
Sebastian Johnston
Keyword(s):  
Immune Responses ◽  
Respiratory Tract ◽  
Respiratory Tract Infections ◽  
Vaccine Development ◽  
Upper Respiratory Tract ◽  
Asthma Exacerbations ◽  
Recent Advances ◽  
Rhinovirus Infection ◽  
Th2 Immune Response ◽  
Tract Infections

Rhinoviruses are the most common cause of upper respiratory tract infections. However, they can induce exacerbations of chronic obstructive pulmonary disease and asthma, bronchiolitis in infants, and significant lower respiratory tract infections in children, the immunosuppressed, and the elderly. The large number of rhinovirus strains (currently about 160) and their antigenic diversity are significant obstacles in vaccine development. The phenotype of immune responses induced during rhinovirus infection can affect disease severity. Recognition of rhinovirus and a balance of innate responses are important factors in rhinovirus-induced morbidity. Immune responses to rhinovirus infections in healthy individuals are typically of the T helper type 1 (Th1) phenotype. However, rhinovirus-driven asthma exacerbations are additionally characterised by an amplified Th2 immune response and airway neutrophilia. This commentary focuses on recent advances in understanding immunity toward rhinovirus infection and how innate and adaptive immune responses drive rhinovirus-induced asthma exacerbations.

Recent Advances in High Dispersion Spectroscopy of Globular Cluster Stars

1988 ◽  
Vol 132 ◽  
pp. 525-530
Author(s):  
Raffaele G. Gratton
Keyword(s):  
Globular Cluster ◽  
Globular Clusters ◽  
High Dispersion ◽  
Photographic Material ◽  
Recent Advances ◽  
Metal Abundances ◽  
Ccd Detectors ◽  
Major Progress

The use CCD detectors has allowed a major progress in abundance derivations for globular cluster stars in the last years. Abundances deduced from high dispersion spectra now correlates well with other abundance indicators. I discuss some problems concerning the derivation of accurate metal abundances for globular clusters using high dispersion spectra from both the old photographic and the most recent CCD data. The discrepant low abundances found by Cohen (1980), from photographic material for M71 giants, are found to be due to the use of too high microturbulences.

New Ultrastructural Observations on Injury and Regeneration of Cilia in Mammalian Conducting Airway Epithelium

1981 ◽  
Vol 39 ◽  
pp. 624-625
Author(s):  
J.L. Carson ◽  
A.M. Collier
Keyword(s):  
Respiratory Tract ◽  
Airway Epithelium ◽  
Defense Mechanisms ◽  
Normal Growth ◽  
Fetal Lung ◽  
Secretory Cells ◽  
Airway Epithelial ◽  
Ciliated Cells ◽  
Conducting Airway ◽  
Conducting Airways

The ciliated cells lining the conducting airways of mammals are integral to the defense mechanisms of the respiratory tract, functioning in coordination with secretory cells in the removal of inhaled and cellular debris. The effects of various infectious and toxic agents on the structure and function of airway epithelial cell cilia have been studied in our laboratory, both of which have been shown to affect ciliary ultrastructure.These observations have led to questions about ciliary regeneration as well as the possible induction of ciliogenesis in response to cellular injury. Classical models of ciliogenesis in the conducting airway epithelium of the mammalian respiratory tract have been based primarily on observations of the developing fetal lung. These observations provide a plausible explanation for the embryological generation of ciliary beds lining the conducting airways but do little to account for subsequent differentiation of ciliated cells and ciliogenesis during normal growth and development.

Sign in / Sign up

Export Citation Format

Share Document