Kinetic Parameters of Fed-Batch Production of Carotenoids by Sporidiobolus salmonicolor Using Low-Cost Agro-Industrial Substrates

2019 ◽  
Vol 15 (5) ◽  
pp. 311-321
Author(s):  
Rosicler Colet ◽  
Letícia Urnau ◽  
Guilherme De Souza Hassemer ◽  
Bruna Bernar Dias ◽  
Jamile Zeni ◽  
...  
Keyword(s):  
Kinetic Parameters ◽  
Low Cost ◽  
Fed Batch ◽  
Batch Production ◽  
Sporidiobolus Salmonicolor

Multi-copy expression and fed-batch production of Rhodotorula araucariae epoxide hydrolase in Yarrowia lipolytica

2008 ◽  
Vol 79 (2) ◽  
pp. 235-244 ◽  
Author(s):  
Dheepak Maharajh ◽  
Robyn Roth ◽  
Rajesh Lalloo ◽  
Clinton Simpson ◽  
Robin Mitra ◽  
...  
Keyword(s):  
Yarrowia Lipolytica ◽  
Epoxide Hydrolase ◽  
Fed Batch ◽  
Batch Production

Optimization of fed-batch production of the model recombinant protein GFP inLactococcus lactis

2007 ◽  
Vol 96 (6) ◽  
pp. 1127-1138 ◽  
Author(s):  
Gian M. Oddone ◽  
Christopher Q. Lan ◽  
Helen Rawsthorne ◽  
David A. Mills ◽  
David E. Block
Keyword(s):  
Recombinant Protein ◽  
Fed Batch ◽  
Batch Production

scholarly journals Fed-Batch Production of Saccharomyces cerevisiae L-Asparaginase II by Recombinant Pichia pastoris MUTs Strain

2019 ◽  
Vol 7 ◽  
Author(s):  
David Rodrigues ◽  
Omar Pillaca-Pullo ◽  
Karin Torres-Obreque ◽  
Juan Flores-Santos ◽  
Ignacio Sánchez-Moguel ◽  
...  
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Pichia Pastoris ◽  
Fed Batch ◽  
Batch Production ◽  
Recombinant Pichia Pastoris

Serum free fed batch production of IgM

1986 ◽  
Vol 8 (7) ◽  
pp. 457-462 ◽  
Author(s):  
John P. Tharakan ◽  
Pao C. Chau
Keyword(s):  
Fed Batch ◽  
Batch Production ◽  
Serum Free

scholarly journals Fed-Batch Production of Bacterial Ghosts Using Dielectric Spectroscopy for Dynamic Process Control

2016 ◽  
Vol 4 (2) ◽  
pp. 18 ◽  
Author(s):  
Andrea Meitz ◽  
Patrick Sagmeister ◽  
Werner Lubitz ◽  
Christoph Herwig ◽  
Timo Langemann
Keyword(s):  
Process Control ◽  
Dynamic Process ◽  
Dielectric Spectroscopy ◽  
Fed Batch ◽  
Batch Production ◽  
Bacterial Ghosts

scholarly journals Thermodynamic and Aerodynamic Analysis of an Air-Driven Fan System in Low-Cost High-Bypass-Ratio Turbofan Engine

Energies ◽  
2019 ◽  
Vol 12 (10) ◽  
pp. 1917 ◽  
Author(s):  
Weiyu Lu ◽  
Guoping Huang ◽  
Xin Xiang ◽  
Jinchun Wang ◽  
Yuxuan Yang
Keyword(s):  
Numerical Simulation ◽  
Design Principle ◽  
Low Cost ◽  
Complex Structure ◽  
Batch Production ◽  
Turbofan Engine ◽  
The Core ◽  
And Performance ◽  
Core Part ◽  
Bypass Ratio

In some cases, the improvement of the bypass ratio (BPR) of turbofans is pursued for military or civilian purposes owing to economic, environmental, and performance reasons, among others. However, high-BPR turbofans suffer from incompatibility of spool speed, complex structure for manufacture, development difficulty, and substantially increasing costs, especially for those with small batch production. To deal with the issues, a novel low-cost concept of high-BPR turbofan with air-driven fan (ADTF) is presented in this research. First, the problems faced by high-BPR turbofans are discussed, and the difficulties of geared turbofan (GTF), which is developed as a solution to the problems, are analyzed. A novel turbofan with potential advantages is proposed, and its basic theory is interpreted. Second, high-BPR ADTF is analyzed at the top level, and the design principle and important primary parameters are discussed. Some important concepts and criteria are proposed, enabling the comparison between ADTF and GTF. Finally, an air-driven fan system, the core part of ADTF, is exploratorily designed, and numerical simulation is performed to demonstrate its feasibility.

scholarly journals Probeless non-invasive near-infrared spectroscopic bioprocess monitoring using microspectrometer technology

2019 ◽  
Vol 412 (9) ◽  
pp. 2103-2109 ◽  
Author(s):  
Robert Zimmerleiter ◽  
Julian Kager ◽  
Ramin Nikzad-Langerodi ◽  
Vladimir Berezhinskiy ◽  
Frank Westad ◽  
...  
Keyword(s):  
Real Time ◽  
Process Parameters ◽  
Near Infrared ◽  
Low Cost ◽  
Phenoxyacetic Acid ◽  
Bioprocess Monitoring ◽  
Fed Batch ◽  
Precise Control ◽  
Fed Batch Fermentation ◽  
Using Data

AbstractReal-time measurements and adjustments of critical process parameters are essential for the precise control of fermentation processes and thus for increasing both quality and yield of the desired product. However, the measurement of some crucial process parameters such as biomass, product, and product precursor concentrations usually requires time-consuming offline laboratory analysis. In this work, we demonstrate the in-line monitoring of biomass, penicillin (PEN), and phenoxyacetic acid (POX) in a Penicilliumchrysogenum fed-batch fermentation process using low-cost microspectrometer technology operating in the near-infrared (NIR). In particular, NIR reflection spectra were taken directly through the glass wall of the bioreactor, which eliminates the need for an expensive NIR immersion probe. Furthermore, the risk of contaminations in the reactor is significantly reduced, as no direct contact with the investigated medium is required. NIR spectra were acquired using two sensor modules covering the spectral ranges 1350–1650 nm and 1550–1950 nm. Based on offline reference analytics, partial least squares (PLS) regression models were established for biomass, PEN, and POX either using data from both sensors separately or jointly. The established PLS models were tested on an independent validation fed-batch experiment. Root mean squared errors of prediction (RMSEP) were 1.61 g/L, 1.66 g/L, and 0.67 g/L for biomass, PEN, and POX, respectively, which can be considered an acceptable accuracy comparable with previously published results using standard process spectrometers with immersion probes. Altogether, the presented results underpin the potential of low-cost microspectrometer technology in real-time bioprocess monitoring applications.

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