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A Stable Producer Cell Line for the Manufacture of a Lentiviral Vector for Gene Therapy of Parkinson's Disease
Human Gene Therapy
◽
10.1089/hum.2010.142
◽
2011
◽
Vol 22
(3)
◽
pp. 357-369
◽
Cited By ~ 21
Author(s):
Hannah J. Stewart
◽
Liang Fong-Wong
◽
Iain Strickland
◽
Daniel Chipchase
◽
Michelle Kelleher
◽
...
Keyword(s):
Parkinson’S Disease
◽
Gene Therapy
◽
Parkinson's Disease
◽
Cell Line
◽
Lentiviral Vector
◽
Producer Cell Line
◽
Producer Cell
Download Full-text
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References
458. Development of a Stable Producer Cell Line for Scalable Lentiviral Vector Production for Gene Therapy of Hemoglobinopathie
Molecular Therapy
◽
10.1016/s1525-0016(16)33267-1
◽
2016
◽
Vol 24
◽
pp. S182
Author(s):
Sarah Slauson
◽
Amelia Thomas
◽
Byoung Ryu
◽
Melissa Bonner
◽
Gretchen Lewis
◽
...
Keyword(s):
Gene Therapy
◽
Cell Line
◽
Lentiviral Vector
◽
Producer Cell Line
◽
Producer Cell
Download Full-text
82. Adaptation of a Lentiviral Vector Producer Cell Line to Reduced-Serum, Suspension Culture for Large Scale Production
Molecular Therapy
◽
10.1016/j.ymthe.2004.06.018
◽
2004
◽
Vol 9
◽
pp. S33
Keyword(s):
Suspension Culture
◽
Cell Line
◽
Large Scale
◽
Lentiviral Vector
◽
Scale Production
◽
Producer Cell Line
◽
Large Scale Production
◽
Producer Cell
Download Full-text
Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial
The Lancet
◽
10.1016/s0140-6736(13)61939-x
◽
2014
◽
Vol 383
(9923)
◽
pp. 1138-1146
◽
Cited By ~ 247
Author(s):
Stéphane Palfi
◽
Jean Marc Gurruchaga
◽
G Scott Ralph
◽
Helene Lepetit
◽
Sonia Lavisse
◽
...
Keyword(s):
Parkinson’S Disease
◽
Gene Therapy
◽
Parkinson's Disease
◽
Dose Escalation
◽
Lentiviral Vector
◽
Phase 1
◽
Open Label
◽
Open Label Phase
Download Full-text
Faculty Opinions recommendation of Long-term safety and tolerability of ProSavin, a lentiviral vector-based gene therapy for Parkinson's disease: a dose escalation, open-label, phase 1/2 trial.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
◽
10.3410/f.718235629.793491568
◽
2014
◽
Author(s):
Joseph Jankovic
◽
Mary Ann Thenganatt
Keyword(s):
Parkinson’S Disease
◽
Gene Therapy
◽
Parkinson's Disease
◽
Dose Escalation
◽
Lentiviral Vector
◽
Phase 1
◽
Open Label
◽
Open Label Phase
Download Full-text
Delayed gene therapy of glial cell line-derived neurotrophic factor is efficacious in a rat model of Parkinson's disease
Molecular Brain Research
◽
10.1016/j.molbrainres.2004.06.029
◽
2005
◽
Vol 134
(1)
◽
pp. 155-161
◽
Cited By ~ 29
Author(s):
Jie-Sheng Zheng
◽
Ling-Ling Tang
◽
Shu-Sen Zheng
◽
Ren-Ya Zhan
◽
Yong-Qing Zhou
◽
...
Keyword(s):
Parkinson’S Disease
◽
Gene Therapy
◽
Parkinson's Disease
◽
Cell Line
◽
Glial Cell
◽
Rat Model
◽
Neurotrophic Factor
Download Full-text
Gene therapy process change evaluation framework: transient transfection and stable producer cell line comparison
Biochemical Engineering Journal
◽
10.1016/j.bej.2021.108202
◽
2021
◽
pp. 108202
Author(s):
Ruxandra-Maria Comisel
◽
Bo Kara
◽
Frederick H Fiesser
◽
Suzanne S Farid
Keyword(s):
Gene Therapy
◽
Cell Line
◽
Transient Transfection
◽
Evaluation Framework
◽
Therapy Process
◽
Process Change
◽
Producer Cell Line
◽
Producer Cell
Download Full-text
Long-Term Follow-Up of a Phase I/II Study of ProSavin, a Lentiviral Vector Gene Therapy for Parkinson's Disease
Human Gene Therapy Clinical Development
◽
10.1089/humc.2018.081
◽
2018
◽
Vol 29
(3)
◽
pp. 148-155
◽
Cited By ~ 36
Author(s):
Stéphane Palfi
◽
Jean Marc Gurruchaga
◽
Hélène Lepetit
◽
Katy Howard
◽
G. Scott Ralph
◽
...
Keyword(s):
Parkinson’S Disease
◽
Gene Therapy
◽
Parkinson's Disease
◽
Phase I
◽
Lentiviral Vector
◽
Long Term Follow Up
Download Full-text
379. GMP Production of a SIN Lentiviral Vector for the Treatment of SCID-X1 Using a Stable Producer Cell Line
Molecular Therapy
◽
10.1016/s1525-0016(16)36951-9
◽
2011
◽
Vol 19
◽
pp. S148
Keyword(s):
Cell Line
◽
Lentiviral Vector
◽
Producer Cell Line
◽
Producer Cell
◽
Gmp Production
Download Full-text
Gene Therapy for Parkinson’s Disease: AAV5-Mediated Delivery of Glial Cell Line-Derived Neurotrophic Factor (GDNF)
Neuromethods - Gene Delivery and Therapy for Neurological Disorders
◽
10.1007/978-1-4939-2306-9_3
◽
2015
◽
pp. 67-83
◽
Cited By ~ 2
Author(s):
Bas Blits
◽
Deniz Kirik
◽
Harald Petry
◽
Stephan Hermening
Keyword(s):
Parkinson’S Disease
◽
Gene Therapy
◽
Parkinson's Disease
◽
Cell Line
◽
Glial Cell
◽
Neurotrophic Factor
Download Full-text
861. Transduction of Human CD34+ Derived NOG Repopulating Cells with an Insulated SIN Lentiviral Vector for SCID-X1 Produced from a Stable Producer Cell Line
Molecular Therapy
◽
10.1016/s1525-0016(16)38302-2
◽
2010
◽
Vol 18
◽
pp. S333
Keyword(s):
Cell Line
◽
Lentiviral Vector
◽
Producer Cell Line
◽
Human Cd34
◽
Producer Cell
Download Full-text
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