Rate-Pressure Product Responses to Static Contractions Performed at Various Altitudes

2021 ◽  
Author(s):  
Michael J. Simmonds ◽  
Surendran Sabapathy ◽  
Jean-Marc Hero
Keyword(s):  
Rate Pressure Product ◽  
Static Contractions

Hubungan antara peningkatan rate pressure product dan uji jalan 6 menit pada pasien dengan gagal jantung kronis

2019 ◽  
Vol 50 (3) ◽  
Author(s):  
Primeriana Nugiaswari ◽  
K. Badjra Nadha ◽  
Raka Widiana
Keyword(s):  
Rate Pressure Product

CARDIORESPIRATORY SYSTEM UNDER BICYCLE ERGOMETER TEST IN SKIERS WITH DIFFERENT TRAINING STATUS (KOMI REPUBLIC)

2019 ◽  
pp. 76-84
Author(s):  
Yu.G. Solonin ◽  
T.P. Loginova ◽  
I.O. Garnov ◽  
A.L. Markov ◽  
A.A. Chernykh ◽  
...  
Keyword(s):  
Heart Rate ◽  
Oxygen Consumption ◽  
Komi Republic ◽  
Rate Pressure Product ◽  
Training Status ◽  
Maximum Oxygen Consumption ◽  
Bicycle Ergometry ◽  
Cardiorespiratory System ◽  
Unit Pulse ◽  
Ski Racers

The aim of the study is to examine the impact of training status on ski racers (Komi Republic) at rest and under bicycle ergometry evaluating their cardiorespiratory system parameters. Materials and Methods. The authors examined male ski racers with different training status: 22 first-rank sportsmen, 22 candidates for Master of Sports and 22 Masters of Sports. Athletes underwent bicycle ergometry loads up to refusal. Oxycon Pro system (Germany) was used. Then authors studied the complex of cardiorespiratory parameters, calculating maximum oxygen consumption and unit physiological cost. Results. At rest and under standard physical load (200 W) Masters of Sports demonstrate significantly increased training status among ski racers in such cardiorespiratory system parameters as heart rate, rate pressure product and oxygen pulse. Under standard physical load (200 W) statistically significant differences between first-rank sportsmen and candidates for Master of Sports are detected by heart rate, rate pressure product, respiration rate, respiratory minute volume and oxygen utilization coefficient. Such deviations indicate differences in training status. Under maximum load, the highest training status is found in Masters of Sports: bicycle ergometry load power and duration; unit pulse, pressor and cardiac cost, bulk and unit values of maximum oxygen consumption. Heart rate values, unit pulse and heart-vent cost indicate a high training status in candidates for Master of Sports under load up to refusal, if compared with first-rank sportsmen. Athletes’ organism under load up to refusal works more efficiently than under moderate load (200 W). The training status in ski racers (Komi Republic) is manifested in the saving cardiorespiratory system functions, both at rest and under standard bicycle ergometry, as well as in parameters of unit physiological cost under loads up to refusal and increased values of maximum oxygen consumption. Keywords: ski racers, Komi Republic, training status, bicycle ergometry loads, cardiorespiratory system, maximum oxygen consumption.

Rate-pressure product and myocardial oxygen consumption during surgery for coronary artery bypass.

Circulation ◽  
1979 ◽  
Vol 60 (2) ◽  
pp. 170-173 ◽  
Author(s):  
P L Wilkinson ◽  
J R Moyers ◽  
T Ports ◽  
K Chatterjee ◽  
D Ullyott ◽  
...  
Keyword(s):  
Oxygen Consumption ◽  
Coronary Artery ◽  
Coronary Artery Bypass ◽  
Myocardial Oxygen Consumption ◽  
Artery Bypass ◽  
Rate Pressure Product

Abstract P218: The Association Of Mid-life Cumulative Exposure To Systolic Blood Pressure, Myocardial Oxygen Demand, And Hypertension With Later-life Central Arterial Stiffness And Its 5-year Change: The Atherosclerosis Risk In Communities Study - Neurocognitive Study (ARIC-NCS)

Circulation ◽  
2021 ◽  
Vol 143 (Suppl_1) ◽  
Author(s):  
Michelle L Meyer ◽  
Veeral Saraiya ◽  
Hirofumi Tanaka ◽  
Priya Palta ◽  
Timothy M Hughes ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Arterial Stiffness ◽  
Systolic Blood Pressure ◽  
Oxygen Demand ◽  
Later Life ◽  
Cumulative Exposure ◽  
Rate Pressure Product ◽  
Myocardial Oxygen Demand ◽  
Small Magnitude ◽  
Cumulative Exposures

Background: Greater central artery stiffness predicts cardiovascular disease and all-cause mortality, thus understanding arterial stiffness determinants has prevention implications. Reports of the temporal association of blood pressure with arterial stiffness are conflicting and the association with myocardial oxygen demand has not been evaluated. Objective: Characterize the association of mid- to later-life cumulative exposure to systolic blood pressure (SBP), myocardial oxygen demand, and hypertension (HTN) with arterial stiffness and its 5-year change in older adults. Methods: We included 1,975 adults (1151 women; 359 Black; visit 5 mean age 74 years) examined in visits 5 (2011-13) and 6 or 7 (2016-19) of the population-based ARIC-NCS with measures of arterial stiffness (carotid-femoral pulse wave velocity (cfPWV)). Higher cfPWV indicates greater arterial stiffness. We calculated cumulative exposures as the sum of averages from four consecutive visits from 1987-89 to 1996-98 divided by total time. Myocardial oxygen demand was calculated as the rate pressure product (RPP): (SBP x heart rate)/1,000. We derived HTN duration as the time since first HTN detection. Associations of cumulative exposures with visit 5 cfPWV and the 5-year cfPWV change were evaluated by multivariable linear regression adjusted for demographics and cardiometabolic factors. Results: Over the mean 5.7 years between visits 5 and 6 or 7, cfPWV increased by 144.9 cm/s (SD: 276.0; range -680.0, 961.5 cm/s). HTN at any visit, duration, and the time-weighted cumulative measures were associated with higher visit 5 cfPWV (Table). Prevalent HTN was inversely associated with cfPWV change. No statistically significant associations were observed for the other exposures and cfPWV change. Conclusion: Cumulative exposure to SBP, RPP, and HTN are modifiable traits associated with higher cfPWV at later-life, but not with rate of cfPWV change in older adulthood. HTN at visit 5 was associated with lower cfPWV change, albeit the change is of small magnitude.

Abstract 17321: Race Differences in Hemodynamic Responses to Acute Mental Stress and the Role of Depressive Symptoms

Circulation ◽  
2014 ◽  
Vol 130 (suppl_2) ◽  
Author(s):  
Kobina A Wilmot ◽  
Ibhar Al Mheid ◽  
Ronnie Ramadan ◽  
Pratik M Pimple ◽  
Amit J Shah ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Depressive Symptoms ◽  
African Americans ◽  
Mental Stress ◽  
Rate Pressure Product ◽  
Hemodynamic Responses ◽  
Explanatory Role ◽  
The Difference ◽  
Hemodynamic Reactivity ◽  
Different Response

Introduction: Increased hemodynamic responses to psychological stress have been associated with adverse CAD events. African Americans (AA) have worse CAD outcomes than other groups. Heightened hemodynamic responses to stress may play a role. Our hypothesis was that AA would have higher hemodynamic reactivity to a standardized mental stress compared to Non-African Americans (NAA). Methods: We evaluated 574 patients (163 AA) with CAD, who underwent a standardized mental stress challenge. Hemodynamics were obtained at rest, during stress (speaking task), and during recovery. The rate-pressure product (RPP) was calculated as systolic blood pressure (SBP) x heart rate (HR). Hemodynamic reactivity was evaluated as the difference in RPP at rest and during stress. Depressive symptoms were measured with the Beck Depression Inventory-II (BDI). Results: As compared to NAA, AA patients were younger, had lower education and income, and higher prevalence of diabetes, obesity, hypertension, smoking, and depressive symptoms (BDI mean scores 9.8 vs. 7.6, p= 0.003). AA patients had higher blood pressure during all three periods (Table). However, hemodynamic reactivity with stress was significantly lower in AA than NAA (RPP reactivity 3114 vs 3620, p= 0.02). Adjusting for baseline RPP, age, gender and smoking did not substantially alter the association. However, after adjusting for depressive symptoms, the association was attenuated by 23% (p=0.16). BMI, diabetes and beta-blocker use had minimal additional explanatory role. In the final model, baseline RPP, depressive symptoms and BMI were significantly associated with a lower RPP reactivity (p<0.01). Conclusion: AA patients with CAD, compared with NAA, have elevated blood pressure throughout mental stress, but tend to have blunted hemodynamic reactivity to stress. Depressive symptoms, which are more elevated among AA, play a role in this different response to stress and may be implicated in the higher CAD risk of this group.

Abstract 223: The Role Of Angiogenesis In The Myocardial Ischemia/reperfusion Injury In Pregnancy

2014 ◽  
Vol 115 (suppl_1) ◽  
Author(s):  
Jingyuan li ◽  
Zoltan Pierre Arany ◽  
Mansoureh Eghbali
Keyword(s):  
Infarct Size ◽  
Ischemia Reperfusion Injury ◽  
Heart Function ◽  
Ischemia Reperfusion ◽  
Angiogenic Factor ◽  
Daily Injection ◽  
Rate Pressure Product ◽  
Ctrl Group ◽  
The Impact ◽  
In Pregnancy

Angiogenesis plays an important role in the pathogenesis of cardiovascular disease. Pro-angiogenic and anti-angiogenic treatments have provided new insights into the impact of angiogenesis-based approaches on coronary artery disease. We have recently reported that the hearts of late pregnant (LP) mice are more prone to ischemia/reperfusion (I/R) injury compared to non pregnant(NP) mice. Provided the significant change of angiogenesis status in pregnancy, here we explored whether stimulating the angiogenesis with VEGF is able to protect the heart against I/R injury in late pregnancy, and whether anti-antigenic treatment with soluble endoglin(sENG), an anti-angiogenic factor, aggravates cardiac I/R injury in NP. Pregnant mice at day 12 either received daily injection of VEGF (100 ug/kg daily subcutaneous injection) or PBS(LP CTRL) for 7 days, and at day 19 the LP mice hearts were subjected to 20 min ischemia followed by 40 min reperfusion in Langendorff. NP mice either received a single adenovirus sENG(2х10 8particles via tail vein injection) or vehicle(NP CTRL), and 10 days later NP mice were subjected to 20 min ischemia followed by 40 min reperfusion in Langendorff. The heart function was recorded throughout the experiments, and the infarct size was measured by TTC staining at the end of experiments. Exogenous VEGF treatment significantly improved the cardiac function of LP mice after ischemia. The rate pressure product (RPP) at the end of reperfusion was improved from 1617±287 mmHg*beats/min (n=6) in LP CTRL to 11287±1783 mmHg*beats/min (n=3) in the VEGF group(p<0.01). The infarct size was also significantly reduced by VEGF treatment to 25.0±4.3% (n=3) from 57.4±5.2%(n=6) in CTRL (p<0.01). While sENG aggravated the cardiac I/R injury in NP, as the RPP at the end of reperfusion in the sENG group (4523±1281 mmHg*beats/min, n=4) was significantly lower compared with NP CTRL group(12818±1213 mmHg*beats/min, n=6)(p<0.01). Furthermore, the infarct size in the sENG group was markedly higher compared with NP CTRL group (34.0±3.3% (n=4) vs. 16.3±1.4%(n=6) in NP CTRL, p<0.05). In conclusion, anti-angiogenic treatment aggravates the cardiac I/R injury in NP, while angiogenic therapy protects the heart against I/R injury in LP.

Effect of yoga on cardiovascular functions and psychological aspects of people on public service-related work: an exploratory study

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Y. Deepa ◽  
A. Mooventhan ◽  
Edmin Christa ◽  
C. A. Kayelarasi
Keyword(s):  
Blood Pressure ◽  
Public Service ◽  
Tamil Nadu ◽  
Controlled Trial ◽  
Statistical Significance ◽  
Well Being ◽  
Anxiety And Depression ◽  
Rate Pressure Product ◽  
Clinical Difference ◽  
Cardiovascular Functions

Abstract Objectives Yoga is increasingly being introduced in workplace settings to improve health and well-being. However, there is a lack of studies reporting the effect of yoga in people on public service-related work, who are at high risk for various health-related problems. Thus, the objective of this study was to find the effect of yoga on cardiovascular functions and psychological (stress, anxiety, and depression) aspects of people on public service-related work. Methods A single-group pre-test and post-test experimental study design was adopted. Eighty-two participants aged 41.52 ± 7.44 years who are working in the Tamil Nadu Public Service Commission were undergone 1-h of yoga (under the supervision of a yoga & naturopathy doctor) a day, 5-days a week for a period of 1-month at their office. Cardiovascular functions such as systolic blood pressure (SBP), diastolic blood pressure (DBP), and pulse rate (PR) were measured using an automatic BP monitor. Psychological variables such as stress, anxiety, and depression were measured using Depression Anxiety and Stress Scales (DASS) before and after the intervention. Results Results of this study showed a significant reduction in body mass index, SBP, DBP, PR, mean arterial pressure, rate pressure product, and double product. Though results showed insignificant (just missed the statistical significance [p=0.056]) reduction in anxiety, it showed clinical improvement (i.e. the mean anxiety score has reduced from moderate category to mild category). However, there is neither statistically significant nor clinical difference in stress and depression. None of the participants reported any untoward events during the study period. Conclusions Results suggest that yoga might improve the cardiovascular functions and anxiety of people in public service-related work. However, no such significant improvement was noted in their stress and depression levels. However, a randomized controlled trial is required to warrant the results of this study.

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