The Effect of an Expiratory Resistance Mask with Dead Space on Sleep, Acute Mountain Sickness, Cognition, and Ventilatory Acclimatization in Normobaric Hypoxia

2019 ◽  
Vol 20 (1) ◽  
pp. 61-70 ◽  
Author(s):  
Alexander Patrician ◽  
Michael M. Tymko ◽  
Hannah G. Caldwell ◽  
Connor A. Howe ◽  
Geoff B. Coombs ◽  
...  
Keyword(s):  
Dead Space ◽  
Acute Mountain Sickness ◽  
Normobaric Hypoxia ◽  
Expiratory Resistance ◽  
Mountain Sickness

No effect of patent foramen ovale on acute mountain sickness and pulmonary pressure in normobaric hypoxia

2021 ◽  
Author(s):  
Kaitlyn G. DiMarco ◽  
Kara M. Beasley ◽  
Karina Shah ◽  
Julia P. Speros ◽  
Jonathan E. Elliott ◽  
...  
Keyword(s):  
Patent Foramen Ovale ◽  
Acute Mountain Sickness ◽  
Normobaric Hypoxia ◽  
Foramen Ovale ◽  
Pulmonary Pressure ◽  
Mountain Sickness

Effect of repeated normobaric hypoxia exposures during sleep on acute mountain sickness, exercise performance, and sleep during exposure to terrestrial altitude

2011 ◽  
Vol 300 (2) ◽  
pp. R428-R436 ◽  
Author(s):  
Charles S. Fulco ◽  
Stephen R. Muza ◽  
Beth A. Beidleman ◽  
Robby Demes ◽  
Janet E. Staab ◽  
...  
Keyword(s):  
Heart Rate ◽  
Exercise Performance ◽  
Hypobaric Hypoxia ◽  
Sham Group ◽  
Acute Mountain Sickness ◽  
Time Trial ◽  
Normobaric Hypoxia ◽  
Performance Decrement ◽  
Mountain Sickness ◽  
End Tidal

There is an expectation that repeated daily exposures to normobaric hypoxia (NH) will induce ventilatory acclimatization and lessen acute mountain sickness (AMS) and the exercise performance decrement during subsequent hypobaric hypoxia (HH) exposure. However, this notion has not been tested objectively. Healthy, unacclimatized sea-level (SL) residents slept for 7.5 h each night for 7 consecutive nights in hypoxia rooms under NH [ n = 14, 24 ± 5 (SD) yr] or “sham” ( n = 9, 25 ± 6 yr) conditions. The ambient percent O2 for the NH group was progressively reduced by 0.3% [150 m equivalent (equiv)] each night from 16.2% (2,200 m equiv) on night 1 to 14.4% (3,100 m equiv) on night 7, while that for the ventilatory- and exercise-matched sham group remained at 20.9%. Beginning at 25 h after sham or NH treatment, all subjects ascended and lived for 5 days at HH (4,300 m). End-tidal Pco2, O2 saturation (SaO2), AMS, and heart rate were measured repeatedly during daytime rest, sleep, or exercise (11.3-km treadmill time trial). From pre- to posttreatment at SL, resting end-tidal Pco2 decreased ( P < 0.01) for the NH (from 39 ± 3 to 35 ± 3 mmHg), but not for the sham (from 39 ± 2 to 38 ± 3 mmHg), group. Throughout HH, only sleep SaO2 was higher (80 ± 1 vs. 76 ± 1%, P < 0.05) and only AMS upon awakening was lower (0.34 ± 0.12 vs. 0.83 ± 0.14, P < 0.02) in the NH than the sham group; no other between-group rest, sleep, or exercise differences were observed at HH. These results indicate that the ventilatory acclimatization induced by NH sleep was primarily expressed during HH sleep. Under HH conditions, the higher sleep SaO2 may have contributed to a lessening of AMS upon awakening but had no impact on AMS or exercise performance for the remainder of each day.

scholarly journals Remote ischemic preconditioning delays the onset of acute mountain sickness in normobaric hypoxia

2015 ◽  
Vol 3 (3) ◽  
pp. e12325 ◽  
Author(s):  
Marc M. Berger ◽  
Hannah Köhne ◽  
Lorenz Hotz ◽  
Moritz Hammer ◽  
Kai Schommer ◽  
...  
Keyword(s):  
Ischemic Preconditioning ◽  
Acute Mountain Sickness ◽  
Normobaric Hypoxia ◽  
Remote Ischemic Preconditioning ◽  
Mountain Sickness

scholarly journals Respiratory alkalinization and posterior cerebral artery dilatation predict acute mountain sickness severity during 10 h normobaric hypoxia

2020 ◽  
Vol 106 (1) ◽  
pp. 175-190
Author(s):  
Holly Barclay ◽  
Saptarshi Mukerji ◽  
Bengt Kayser ◽  
Terrence O'Donnell ◽  
Yu‐Chieh Tzeng ◽  
...  
Keyword(s):  
Cerebral Artery ◽  
Posterior Cerebral Artery ◽  
Acute Mountain Sickness ◽  
Normobaric Hypoxia ◽  
Mountain Sickness

Normobaric hypoxia and symptoms of acute mountain sickness: Elevated brain volume and intracranial hypertension

2014 ◽  
Vol 75 (6) ◽  
pp. 890-898 ◽  
Author(s):  
Justin S. Lawley ◽  
Noam Alperin ◽  
Ahmet M. Bagci ◽  
Sang H. Lee ◽  
Paul G. Mullins ◽  
...  
Keyword(s):  
Intracranial Hypertension ◽  
Brain Volume ◽  
Acute Mountain Sickness ◽  
Normobaric Hypoxia ◽  
Mountain Sickness
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