Frequency of Brain Tissue Embolism Associated with Captive Bolt Gun Stunning of Sheep

2004 ◽  
Vol 1 (4) ◽  
pp. 291-294 ◽  
Author(s):  
R.R. Coore ◽  
S. Love ◽  
C.R. Helps ◽  
M.H. Anil
Keyword(s):  
Brain Tissue ◽  
Tissue Embolism ◽  
Captive Bolt Gun

Brain Tissue Fragments in Jugular Vein Blood of Cattle Stunned by Use of Penetrating or Nonpenetrating Captive Bolt Guns

2005 ◽  
Vol 68 (4) ◽  
pp. 882-884 ◽  
Author(s):  
R. R. COORE ◽  
S. LOVE ◽  
J. L. McKINSTRY ◽  
H. R. WEAVER ◽  
A. PHILIPS ◽  
...  
Keyword(s):  
United Kingdom ◽  
Confidence Interval ◽  
Brain Tissue ◽  
Jugular Vein ◽  
Venous Blood ◽  
Spongiform Encephalopathy ◽  
Blood Samples ◽  
The United Kingdom ◽  
Captive Bolt Gun ◽  
Carcass Contamination

Although the incidence of bovine spongiform encephalopathy in cattle continues to decline in the United Kingdom, it remains important to maintain vigilance of all potential routes of transmission of infection to humans. Initial studies have demonstrated a potential risk of carcass contamination with brain tissue following the use of captive bolt gun stunning in cattle. The objective of this study was to further explore these initial findings particularly in regard to captive bolt guns currently in use in the United Kingdom. Brain tissue fragments or elevated levels of a marker protein for brain tissue were detected in venous blood samples from 4% (95% confidence interval, 1.6 to 9.8%) of cattle stunned by penetrating captive bolt gun and from 2% (95% confidence interval, 0.6 to 7%) of those stunned by nonpenetrating captive bolt gun.

Massive Brain Tissue and Fat Pulmonary Embolism following Severe Head Injury

1987 ◽  
Vol 27 (2) ◽  
pp. 128-131 ◽  
Author(s):  
J. M. Torry
Keyword(s):  
Brain Tissue ◽  
Severe Head Injury ◽  
Post Mortem ◽  
Embolic Material ◽  
Lung Lobe ◽  
Frequent Finding ◽  
Lower Lung ◽  
Tissue Embolism ◽  
The Right ◽  
Severe Fracture

The case described is that of a 60-year-old male who fell from a ladder and sustained a severe fracture of the skull. At post-mortem an established infarct of the right lower lung lobe was found, related to an unusually pale embolus in the lobar artery and its branches. Histological examination demonstrated the embolic material to be composed of brain tissue. Tissue embolism to the pulmonary tree is a frequent finding in traumatic deaths but the unusual nature of this case is worthy of note.

Effects of therapeutic and toxic phenobarbital doses on brain tissue caspase 3-activity in the neonatal rat

2006 ◽  
Vol 37 (03) ◽  
Author(s):  
R Husain ◽  
HS Fink ◽  
K Lang ◽  
B Merkle ◽  
R Bauer ◽  
...  
Keyword(s):  
Brain Tissue ◽  
Caspase 3 ◽  
Neonatal Rat

Effects of Hormone Replacement Therapy on Plasma and Tissue Fibrinolytic Activity in a Rat Model of Surgically Induced Menopause

2014 ◽  
Vol 37 (2) ◽  
pp. 85 ◽  
Author(s):  
Ata Topcuoglu ◽  
Mustafa Albayrak ◽  
Hayriye Erman ◽  
Huriye Balci ◽  
Mesut Karakus ◽  
...  
Keyword(s):  
Hormone Replacement Therapy ◽  
Oral Administration ◽  
Replacement Therapy ◽  
Plasminogen Activator ◽  
Brain Tissue ◽  
Fibrinolytic Activity ◽  
Hormone Replacement ◽  
17Β Estradiol ◽  
Surgically Induced ◽  
Pai 1

Purpose: The purpose of this study was to analyze the effects of estrogen deficiency and hormone replacement therapy (HRT) on fibrinolytic activity in a rat mode of surgically-induced menopause. Methods: Twelve-week-old, sexually mature female Sprague-Dawley rats, each weighing 200–250 g, were randomly divided into four groups: (1) sham-operated group, (2) ovariectomy group, (3) ovariectomy group followed by oral administration of daily 17β-estradiol (0.02 mg/kg/day) (E2) + norethisterone acetate (0.01 mg/kg/day), and (4) ovariectomy group followed by oral administration of daily 17β-estradiol (0.01 mg/kg/day) + drospirenone (0.02 mg/kg/day). Tissue plasminogen activator (tPA) antigen, plasminogen activator inhibitor-1 (PAI-1) antigen, and PAI-1/tPA levels were measured as markers of fibrinolysis in plasma and liver and brain tissue. Results: Compared with sham-operated rats, ovariectomized rats showed higher levels of fibrinolytic activity; however, the increased fibrinolytic activity in plasma and liver tissue was significantly reduced by HRT regimens. No change was observed in the levels of fibrinolytic activity in brain tissue. Conclusions: HRT showed beneficial effects by decreasing fibrinolytic activity related to surgically-induced menopause. Short-term HRT treatment was associated with a shift in the procoagulant-anticoagulant balance toward a procoagulant state.

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