Irreversible Electroporation for Renal Ablation Does Not Cause Significant Injury to Adjacent Ureter or Bowel in a Porcine Model

2020 ◽  
Author(s):  
Igor Sorokin ◽  
Noah Canvasser ◽  
Brett Johnson ◽  
Elena Lucas ◽  
Jeffrey A. Cadeddu
Keyword(s):  
Porcine Model ◽  
Irreversible Electroporation ◽  
Renal Ablation ◽  
Significant Injury

Assessment of Chronological Effects of Irreversible Electroporation on Hilar Bile Ducts in a Porcine Model

2013 ◽  
Vol 37 (1) ◽  
pp. 224-230 ◽  
Author(s):  
Jae Woong Choi ◽  
David S. K. Lu ◽  
Ferdnand Osuagwu ◽  
Steven Raman ◽  
Charles Lassman
Keyword(s):  
Bile Ducts ◽  
Porcine Model ◽  
Irreversible Electroporation

Comparison of renal ablation with cryotherapy, dry radiofrequency, and saline augmented radiofrequency in a porcine model 1 1No competing interests declared.

2001 ◽  
Vol 193 (5) ◽  
pp. 505-513 ◽  
Author(s):  
William C. Collyer ◽  
Jaime Landman ◽  
Ephrem O. Olweny ◽  
Cassio Andreoni ◽  
Kurt Kerbl ◽  
...  
Keyword(s):  
Porcine Model ◽  
Competing Interests ◽  
Renal Ablation

scholarly journals Robotically-Assisted Sonic Therapy for Renal Ablation in a Live Porcine Model: Initial Preclinical Results

2019 ◽  
Vol 30 (8) ◽  
pp. 1293-1302 ◽  
Author(s):  
Emily A. Knott ◽  
John F. Swietlik ◽  
Katherine C. Longo ◽  
Rao F. Watson ◽  
Chelsey M. Green ◽  
...  
Keyword(s):  
Porcine Model ◽  
Renal Ablation

scholarly journals Long-term clinical and pathological outcomes after irreversible electroporation of the pancreas using two parallel plate electrodes: a porcine model

HPB ◽  
2017 ◽  
Vol 19 ◽  
pp. S151
Author(s):  
S. Rombouts ◽  
W. van Dijck ◽  
M. Nijkamp ◽  
T. Derksen ◽  
L. Brosens ◽  
...  
Keyword(s):  
Parallel Plate ◽  
Porcine Model ◽  
Irreversible Electroporation

Efficacy of multi-electrode linear irreversible electroporation

EP Europace ◽  
2020 ◽  
Author(s):  
Thomas J Buist ◽  
Marijn H A Groen ◽  
Fred H M Wittkampf ◽  
Peter Loh ◽  
Pieter A F M Doevendans ◽  
...  
Keyword(s):  
Porcine Model ◽  
Random Sequence ◽  
Irreversible Electroporation ◽  
Median Sternotomy ◽  
Interquartile Range ◽  
Electrode Spacing ◽  
Peak Current ◽  
Histological Sections ◽  
Good Contact

Abstract Aims We investigated the efficacy of linear multi-electrode irreversible electroporation (IRE) ablation in a porcine model. Methods and results The study was performed in six pigs (weight 60–75 kg). After median sternotomy and opening of the pericardium, a pericardial cradle was formed and filled with blood. A linear seven polar 7-Fr electrode catheter with 2.5 mm electrodes and 2.5 mm inter-electrode spacing was placed in good contact with epicardial tissue. A single IRE application was delivered using 50 J at one site and 100 J at two other sites, in random sequence, using a standard monophasic defibrillator connected to all seven electrodes connected in parallel. The pericardium and thorax were closed and after 3 weeks survival animals were euthanized. A total of 82 histological sections from all 18 electroporation lesions were analysed. A total of seven 50 J and fourteen 100 J epicardial IRE applications were performed. Mean peak voltages at 50 and 100 J were 1079.2 V ± 81.1 and 1609.5 V ± 56.8, with a mean peak current of 15.4 A ± 2.3 and 20.2 A ± 1.7, respectively. Median depth of the 50 and 100 J lesions were 3.2 mm [interquartile range (IQR) 3.1–3.6] and 5.5 mm (IQR 4.6–6.6) (P < 0.001), respectively. Median lesion width of the 50 and 100 J lesions was 3.9 mm (IQR 3.7–4.8) and 5.4 mm (IQR 5.0–6.3), respectively (P < 0.001). Longitudinal sections showed continuous lesions for 100 J applications. Conclusion Epicardial multi-electrode linear application of IRE pulses is effective in creating continuous deep lesions.

Percutaneous Irreversible Electroporation Lung Ablation: Preliminary Results in a Porcine Model

2011 ◽  
Vol 34 (6) ◽  
pp. 1278-1287 ◽  
Author(s):  
Ajita Deodhar ◽  
Sébastien Monette ◽  
Gordon W. Single ◽  
William C. Hamilton ◽  
Raymond H. Thornton ◽  
...  
Keyword(s):  
Porcine Model ◽  
Irreversible Electroporation ◽  
Preliminary Results

scholarly journals Clinical and pathological outcomes after irreversible electroporation of the pancreas using two parallel plate electrodes: a porcine model

HPB ◽  
2017 ◽  
Vol 19 (12) ◽  
pp. 1058-1065 ◽  
Author(s):  
Steffi J.E. Rombouts ◽  
Willemijn P.M. van Dijck ◽  
Maarten W. Nijkamp ◽  
Tyche C. Derksen ◽  
Lodewijk A.A. Brosens ◽  
...  
Keyword(s):  
Parallel Plate ◽  
Porcine Model ◽  
Irreversible Electroporation
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