Perioperative Antimicrobial Prophylaxis for Preventing Infectious Complications After Transurethral Resection of the Bladder: To Use or Not to Use?

2020 ◽  
Vol 34 (2) ◽  
pp. 198-202 ◽  
Author(s):  
Michele Rizzo ◽  
Enrica Verzotti ◽  
Giacomo Di Cosmo ◽  
Tommaso Cai ◽  
Nicola Pavan ◽  
...  
Keyword(s):  
Transurethral Resection ◽  
Antimicrobial Prophylaxis ◽  
Infectious Complications ◽  
Perioperative Antimicrobial Prophylaxis

Can we avoid routine antimicrobial prophylaxis (AMP) before transurethral resection of the bladder tumor (TURB)?

2019 ◽  
Vol 18 (9) ◽  
pp. e3275
Author(s):  
E. Verzotti ◽  
M. Rizzo ◽  
G. Di Cosmo ◽  
C. Morreale ◽  
A. Marchesin ◽  
...  
Keyword(s):  
Transurethral Resection ◽  
Bladder Tumor ◽  
Antimicrobial Prophylaxis

Discarding antimicrobial prophylaxis for transurethral resection of bladder tumor: A feasibility study

2008 ◽  
Vol 16 (1) ◽  
pp. 61-63 ◽  
Author(s):  
Minato Yokoyama ◽  
Yasuhisa Fujii ◽  
Soichiro Yoshida ◽  
Kazutaka Saito ◽  
Fumitaka Koga ◽  
...  
Keyword(s):  
Feasibility Study ◽  
Transurethral Resection ◽  
Bladder Tumor ◽  
Antimicrobial Prophylaxis

Perioperative antimicrobial prophylaxis in adult patients: The first multicenter clinical practice audit with intervention in Greek surgical departments

2020 ◽  
pp. 1-8
Author(s):  
Elisavet Chorafa ◽  
Elias Iosifidis ◽  
Sotirios Tsiodras ◽  
Athanasios Skoutelis ◽  
Eleni Kourkouni ◽  
...  
Keyword(s):  
Clinical Practice ◽  
Antimicrobial Agents ◽  
Antimicrobial Prophylaxis ◽  
Surgical Site Infections ◽  
Audit And Feedback ◽  
Elective Surgical Procedures ◽  
Before And After ◽  
Greek Hospitals ◽  
Practice Audit ◽  
Perioperative Antimicrobial Prophylaxis

Abstract Objective: To audit clinical practice and implement an intervention to promote appropriate use of perioperative antimicrobial prophylaxis (PAP). Design: Prospective multicenter before-and-after study. Setting: This study was conducted in 7 surgical departments of 3 major Greek hospitals. Methods: Active PAP surveillance in adults undergoing elective surgical procedures was performed before and after implementation of a multimodal intervention. The surveillance monitored use of appropriate antimicrobial agent according to international and local guidelines, appropriate timing and duration of PAP, overall compliance with all 3 parameters and the occurrence of surgical site infections (SSIs). The intervention included education, audit, and feedback. Results: Overall, 1,447 patients were included: 768 before and 679 after intervention. Overall compliance increased from 28.2% to 43.9% (P = .001). Use of antimicrobial agents compliant to international guidelines increased from 89.6% to 96.3% (P = .001). In 4 of 7 departments, compliance with appropriate timing was already >90%; an increase from 44.3% to 73% (P = .001) and from 20.4% to 60% (P = .001), respectively, was achieved in 2 other departments, whereas a decrease from 64.1% to 10.9% (P = .001) was observed in 1 department. All but one department achieved a shorter PAP duration, and most achieved duration of ~2 days. SSIs significantly decreased from 6.9% to 4% (P = .026). After the intervention, it was 2.3 times more likely for appropriate antimicrobial use, 14.7 times more likely to administer an antimicrobial for the appropriate duration and 5.3 times more likely to administer an overall appropriate PAP. Conclusion: An intervention based on education, audit, and feedback can significantly contribute to improvement of appropriate PAP administration; further improvement in duration is needed.

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