Evaluation of the Distribution of Paclitaxel After Application of a Paclitaxel-Coated Balloon in the Rabbit Urethra

2018 ◽  
Vol 32 (5) ◽  
pp. 381-386 ◽  
Author(s):  
Dimitrios Barbalias ◽  
Georgios Lappas ◽  
Panagiotia Ravazoula ◽  
Despoina Liourdi ◽  
Iason Kyriazis ◽  
...  
Keyword(s):  
Rabbit Urethra

HETEROLOGOUS ACELLULAR MATRIX GRAFT FOR RECONSTRUCTION OF THE RABBIT URETHRA: HISTOLOGICAL AND FUNCTIONAL EVALUATION

2001 ◽  
Vol 165 (6 Part 1) ◽  
pp. 2096-2102 ◽  
Author(s):  
KARL-DIETRICH SIEVERT ◽  
JÖRG WEFER ◽  
MUSTAFA EMRE BAKIRCIOGLU ◽  
LORA NUNES ◽  
RAJVIR DAHIYA ◽  
...  
Keyword(s):  
Functional Evaluation ◽  
Acellular Matrix ◽  
Rabbit Urethra

Rabbit Urethra Replacement with a Defined Biomatrix or Small Intestinal Submucosa

2003 ◽  
Vol 44 (2) ◽  
pp. 266-271 ◽  
Author(s):  
J.E. Nuininga ◽  
H. van Moerkerk ◽  
A. Hanssen ◽  
C.A. Hulsbergen ◽  
J. Oosterwijk-Wakka ◽  
...  
Keyword(s):  
Small Intestinal Submucosa ◽  
Rabbit Urethra ◽  
Small Intestinal ◽  
Intestinal Submucosa

scholarly journals Effects of ω-conotoxin on adrenergic, cholinergic and NANC neurotransmission in the rabbit urethra and detrusor

1993 ◽  
Vol 110 (4) ◽  
pp. 1285-1290 ◽  
Author(s):  
P.M. Zygmunt ◽  
P.K.E. Zygmunt ◽  
E.D. Högestätt ◽  
K.-E. Andersson
Keyword(s):  
Rabbit Urethra

Amiloride interacts with [3H]idazoxan and [3H]rauwolscine binding sites in rabbit urethra

1989 ◽  
Vol 164 (1) ◽  
pp. 167-170 ◽  
Author(s):  
Françoise Yablonsky ◽  
Jean Pierre Dausse
Keyword(s):  
Binding Sites ◽  
Rabbit Urethra

Sex differences in function and distribution of alpha 1- and alpha 2-adrenoceptors in rabbit urethra

1987 ◽  
Vol 252 (6) ◽  
pp. F1124-F1128 ◽  
Author(s):  
T. Morita ◽  
J. Latifpour ◽  
B. O'Hollaren ◽  
M. A. Wheeler ◽  
R. M. Weiss
Keyword(s):  
Receptor Binding ◽  
Contractile Response ◽  
Male Urethra ◽  
Binding Studies ◽  
Adrenergic Agonist ◽  
Female Urethra ◽  
Male And Female ◽  
Alpha Adrenoceptors ◽  
Rabbit Urethra ◽  
Urethral Smooth Muscle

To define the functional role of postsynaptic alpha-adrenoceptors in urethral smooth muscle, we examined the effects of various alpha-adrenergic agonists and antagonists on the contractile properties of the isolated urethra of male and female rabbits and quantified the population of alpha 1-and alpha 2-adrenoceptors, using radioligand receptor binding techniques. Norepinephrine (NE), epinephrine, and phenylephrine, an alpha 1-adrenergic agonist, induced increases in contractile force in both the male and female urethra. Clonidine, an alpha 2-adrenergic agonist, caused a relatively large contractile response in the female urethra but only a small contractile response in the male urethra. Receptor binding studies indicated that the male urethra contains almost equal amounts of alpha 1- and alpha 2-adrenoceptors (32 vs. 34 fmol/mg, respectively), whereas the female urethra contains a significantly greater density of alpha 2- than alpha 1-adrenoceptors (122 vs. 34 fmol/mg, respectively). Our studies indicate that both alpha 1- and alpha 2-adrenoceptors cause contractile responses in male and female rabbit urethra; and the greater response to alpha 2-agonist in female than male urethra is correlated with a higher density of alpha 2-adrenoceptors in this tissue.

scholarly journals Characterization of norepinephrine-evoked inward currents in interstitial cells isolated from the rabbit urethra

2002 ◽  
Vol 283 (3) ◽  
pp. C885-C894 ◽  
Author(s):  
G. P. Sergeant ◽  
K. D. Thornbury ◽  
N. G. McHale ◽  
M. A. Hollywood
Keyword(s):  
Reversal Potential ◽  
Cyclopiazonic Acid ◽  
Interstitial Cells ◽  
Equilibrium Potential ◽  
Inward Currents ◽  
Rabbit Urethra ◽  
Patch Technique ◽  
Dependent Mechanism ◽  
Stimulation Of

Freshly dispersed interstitial cells from the rabbit urethra were studied by using the perforated-patch technique. When cells were voltage clamped at −60 mV and exposed to 10 μM norepinephrine (NE) at 80-s intervals, either large single inward currents or a series of oscillatory inward currents of diminishing amplitude were evoked. These currents were blocked by either phentolamine (1 μM) or prazosin (1 μM), suggesting that the effects of NE were mediated via α1-adrenoceptors. NE-evoked currents were depressed by the blockers of Ca2+-activated Cl− currents, niflumic acid (10 μM), and 9-anthracenecarboxylic acid (9-AC, 1 mM). The reversal potential of the above currents changed in a predictable manner when the Cl− equilibrium potential was altered, again suggesting that they were due to activation of a Cl−conductance. NE-evoked currents were decreased by 10 μM cyclopiazonic acid, suggesting that they were dependent on store-released Ca2+. Inhibition of NE-evoked currents by the phospholipase C inhibitor 2-nitro-4-carboxyphenyl- N, N-diphenylcarbamate (100 μM) suggested that NE releases Ca2+ via an inositol 1,4,5-trisphosphate (IP3)-dependent mechanism. These results support the idea that stimulation of α1-adrenoceptors releases Ca2+ from an IP3-sensitive store, which in turn activates Ca2+-activated Cl− current in freshly dispersed interstitial cells of the rabbit urethra. This elevates slow wave frequency in these cells and may underlie the mechanism responsible for increased urethral tone during nerve stimulation.

scholarly journals NANC neurotransmission in lamina propria of the rabbit urethra: regulation by different subsets of calcium channels

1995 ◽  
Vol 115 (6) ◽  
pp. 1020-1026 ◽  
Author(s):  
Pia K.E. Zygmunt ◽  
Peter M. Zygmunt ◽  
Edward D. Högestätt ◽  
Karl-Erik Andersson
Keyword(s):  
Calcium Channels ◽  
Lamina Propria ◽  
Rabbit Urethra
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