Histopathologic Changes After Bipolar Resection of the Prostate: Depth of Penetration of Bipolar Thermal Injury

2012 ◽  
Vol 26 (10) ◽  
pp. 1367-1371 ◽  
Author(s):  
Michael Maddox ◽  
Gyan Pareek ◽  
Shadi Al Ekish ◽  
Simone Thavaseelan ◽  
Akanksha Mehta ◽  
...  
Keyword(s):  
Thermal Injury ◽  
Depth Of Penetration ◽  
Histopathologic Changes

2265 HISTOPATHOLOGIC CHANGES AFTER BIPOLAR RESECTION OF THE PROSTATE: DEPTH OF PENETRATION OF BIPOLAR THERMAL INJURY

2011 ◽  
Vol 185 (4S) ◽  
Author(s):  
Simone Thavaseelan ◽  
Akanksha Mehta ◽  
Gyan Pareek ◽  
George Haleblian
Keyword(s):  
Thermal Injury ◽  
Depth Of Penetration ◽  
Histopathologic Changes

Fractional Laser As Laser Assisted Drug Delivery of Triamcinolone Acetonide in Keloid

2018 ◽  
Vol 3 (1) ◽  
Keyword(s):  
Drug Delivery ◽  
Laser Treatment ◽  
Triamcinolone Acetonide ◽  
Thermal Injury ◽  
Fractional Laser ◽  
Depth Of Penetration ◽  
Burn Scar ◽  
Intralesional Corticosteroid ◽  
Assisted Delivery ◽  
Ablative Fractional Laser

Background: Keloid is benign hyperplasia of dermal collagen which may or may not be preceded by injury in susceptible person. Keloids are refractory to treatment most of the times. Intralesional corticosteroid, topical retinoic acid, topical imiquimod cream, surgery, cryotherapy, laser, and silicon sheeting are mainly used for treatment. Fractional ablative laser is a new laser treatment modality that create numerous microscopic thermal injury zone controlled width, depth, and density that are surrounded by a reservoir of spared epidermal and dermal tissue, allowing of rapid repair of laser-induced thermal injury. Multiple studies demonstrate that laser pretreatment of the skin can increase the permeability and depth of penetration of topical drug molecules. Main observations: A boy, 12 years, scar that arise after burn scar 14 months ago. Scar was felt bigger and thickening also itching. Patient was diagnosed keloid and had been treated with same-session ablative fractional laser and topical triamcinolone acetonide after therapy. Patient had been treated 5 sessions with 3 weeks of interval. Successful of treatment was measured with reduction of keloid size and vancouver scar scale (VSS). Conclusions: Laser assisted drug delivery is an envolving technology with potentially broad clinical application. Ablative fractional laser treatment create vertical channels that might assist the delivery of drug into skin. Combination same-session therapy with ablative fractional laser and triamcinolone acetonide offer a good combination caused assisted delivery of drug.

The Use of Advanced Analytical Techniques for Characterization of the Chemical, Physical, and Crystallographic Nature of a Surface

1973 ◽  
Vol 31 ◽  
pp. 132-133 ◽  
Author(s):  
R. E. Herfert
Keyword(s):  
Surface Characterization ◽  
Analytical Techniques ◽  
X Ray Diffraction ◽  
Depth Of Penetration ◽  
X Ray ◽  
The Past ◽  
Transmission Electron ◽  
Scanning Electron

Studies of the nature of a surface, either metallic or nonmetallic, in the past, have been limited to the instrumentation available for these measurements. In the past, optical microscopy, replica transmission electron microscopy, electron or X-ray diffraction and optical or X-ray spectroscopy have provided the means of surface characterization. Actually, some of these techniques are not purely surface; the depth of penetration may be a few thousands of an inch. Within the last five years, instrumentation has been made available which now makes it practical for use to study the outer few 100A of layers and characterize it completely from a chemical, physical, and crystallographic standpoint. The scanning electron microscope (SEM) provides a means of viewing the surface of a material in situ to magnifications as high as 250,000X.

Cytopathology of Cardiac Tissue from Daunomycin-Treated Mice

1971 ◽  
Vol 29 ◽  
pp. 550-551
Author(s):  
Robert H. Liss ◽  
Frances A. Cotton
Keyword(s):  
Cardiac Tissue ◽  
Cardiac Toxicity ◽  
Drug Distribution ◽  
Personal Communication ◽  
Intravenous Dose ◽  
Single Intravenous Dose ◽  
Physiologic Saline ◽  
Histopathologic Changes ◽  
Distribution Studies ◽  
Lung And Kidney

Daunomycin, an antibiotic used in the clinical management of acute leukemia, produces a delayed, lethal cardiac toxicity. The lethality is dose and schedule dependent; histopathologic changes induced by the drug have been described in heart, lung, and kidney from hamsters in both single and multiple dose studies. Mice given a single intravenous dose of daunomycin (10 mg/kg) die 6-7 days later. Drug distribution studies indicate that the rodents excrete most of a single dose of the drug as daunomycin and metabolite within 48 hours after dosage (M. A. Asbell, personal communication).Myocardium from the ventricles of 6 moribund BDF1 mice which had received a single intravenous dose of daunomycin (10 mg/kg), and from controls dosed with physiologic saline, was fixed in glutaraldehyde and prepared for electron microscopy.

HISTOPATHOLOGIC CHANGES IN RAT ORGANS UPON CHRONIC EXPOSURE TO FORMALDEHYDE VAPOR

2014 ◽  
Vol 13 (2) ◽  
pp. 127-140
Author(s):  
Snur Muhammad Amin Hassan ◽  
Azad Kareem Saeed ◽  
Nabil Abdul-Massih Salmo ◽  
Ahmed Hamdi Mehdi ◽  
Nali Abdulqadr Maaruf
Keyword(s):  
Chronic Exposure ◽  
Rat Organs ◽  
Formaldehyde Vapor ◽  
Histopathologic Changes

Total uncinectomy of the cervical spine with an osteotome: technical note and intraoperative video

2019 ◽  
Vol 31 (6) ◽  
pp. 831-834 ◽  
Author(s):  
Anand H. Segar ◽  
Alexander Riccio ◽  
Michael Smith ◽  
Themistocles S. Protopsaltis
Keyword(s):  
Vertebral Artery ◽  
High Speed ◽  
Thermal Injury ◽  
Technical Note ◽  
Uncinate Process ◽  
Foraminal Stenosis ◽  
Cervical Kyphosis ◽  
Kyphosis Correction ◽  
Direct Injury ◽  
High Speed Burr

Total uncinate process resection or uncinectomy is often required in the setting of severe foraminal stenosis or cervical kyphosis correction. The proximity of the uncus to the vertebral artery, nerve root, and spinal cord makes this a challenging undertaking. Use of a high-speed burr or ultrasonic bone dissector can be associated with direct injury to the vertebral artery and thermal injury to the surrounding structures. The use of an osteotome is a safe and efficient method of uncinectomy. Here the authors describe their technique, which is illustrated with an intraoperative video.

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