Long Noncoding RNA Bladder Cancer Associated Transcript 1 Promotes the Proliferation, Migration, and Invasion of Nonsmall Cell Lung Cancer Through Sponging miR-144

2017 ◽  
Vol 36 (10) ◽  
pp. 845-852 ◽  
Author(s):  
Ji-Ru Ye ◽  
Liang Liu ◽  
Feng Zheng
Keyword(s):  
Lung Cancer ◽  
Bladder Cancer ◽  
Cell Lung Cancer ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Nonsmall Cell Lung Cancer ◽  
Migration And Invasion

scholarly journals Circulating long noncoding RNA GAS5 is a novel biomarker for the diagnosis of nonsmall cell lung cancer

Medicine ◽  
2016 ◽  
Vol 95 (37) ◽  
pp. e4608 ◽  
Author(s):  
Wenjun Liang ◽  
Tangfeng Lv ◽  
Xuefei Shi ◽  
Hongbing Liu ◽  
Qingqing Zhu ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cell Lung Cancer ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Nonsmall Cell Lung Cancer

scholarly journals Long noncoding RNA CYTOR sponges miR-195 to modulate proliferation, migration, invasion and radiosensitivity in nonsmall cell lung cancer cells

2018 ◽  
Vol 38 (6) ◽  
Author(s):  
Jun Zhang ◽  
Wenqi Li
Keyword(s):  
Lung Cancer ◽  
Cell Lung Cancer ◽  
Noncoding Rna ◽  
Nonsmall Cell Lung Cancer ◽  
Underlying Mechanism ◽  
Migration And Invasion ◽  
Functional Roles ◽  
Promising Therapeutic Target ◽  
Microrna Sponge

Nonsmall cell lung cancer (NSCLC) is one of the most frequent malignancies worldwide. Long noncoding RNAs (LncRNAs) play critical roles in cancer initiation and progression. Previous studies have demonstrated that overexpression of cytoskeleton regulator RNA (CYTOR) predicates poor prognosis and promotes tumor progression. However, the functional roles and underlying mechanism of CYTOR in NSCLC remain unknown. In the present study, we found that CYTOR promoted cell proliferation, migration and invasion ability, and induced radioresistance in NSCLC cells. Mechanistically, CYTOR could directly interact with miR-195 and increase its targets. Thus, CYTOR played an oncogenic role in NSCLC progression through sponging miR-195. Together, our study elucidates the role of CYTOR as a microRNA sponge in NSCLC, and CYTOR may be used as a promising therapeutic target for NSCLC treatment.

Long Noncoding RNA SNHG10 Sponges miR-543 to Upregulate Tumor Suppressive SIRT1 in Nonsmall Cell Lung Cancer

2020 ◽  
Vol 35 (10) ◽  
pp. 771-775 ◽  
Author(s):  
Zhe Zhang ◽  
Li Nong ◽  
Meng-Lei Chen ◽  
Xiao-Li Gu ◽  
Wei-Wei Zhao ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cell Lung Cancer ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Nonsmall Cell Lung Cancer
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