In Vivo Binding of Orc2 to a Region of the Chicken Lysozyme GAS41 Origin Containing Multiple Sp1-Binding Sites

2012 ◽  
Vol 31 (2) ◽  
pp. 180-186 ◽  
Author(s):  
Katrin Hübner ◽  
Loc Phi-van
Keyword(s):  
Binding Sites ◽  
In Vivo Binding ◽  
Chicken Lysozyme

scholarly journals De novo identification of in vivo binding sites from ChIP-chip data

2008 ◽  
Vol 9 (S7) ◽  
Author(s):  
Victor Jin ◽  
Alina Rabinovich ◽  
Henny O'Geen ◽  
Sushma Iyengar ◽  
Peggy Farnham
Keyword(s):  
Binding Sites ◽  
De Novo ◽  
Chip Data ◽  
In Vivo Binding ◽  
Chip Chip

scholarly journals E2F in vivo binding specificity: Comparison of consensus versus nonconsensus binding sites

2008 ◽  
Vol 18 (11) ◽  
pp. 1763-1777 ◽  
Author(s):  
A. Rabinovich ◽  
V. X. Jin ◽  
R. Rabinovich ◽  
X. Xu ◽  
P. J. Farnham
Keyword(s):  
Binding Sites ◽  
Binding Specificity ◽  
In Vivo Binding

scholarly journals Genome-Wide Mapping of Collier In Vivo Binding Sites Highlights Its Hierarchical Position in Different Transcription Regulatory Networks

PLoS ONE ◽  
2015 ◽  
Vol 10 (7) ◽  
pp. e0133387 ◽  
Author(s):  
Mathilde de Taffin ◽  
Yannick Carrier ◽  
Laurence Dubois ◽  
Laetitia Bataillé ◽  
Anaïs Painset ◽  
...  
Keyword(s):  
Binding Sites ◽  
Regulatory Networks ◽  
In Vivo Binding ◽  
Genome Wide ◽  
Hierarchical Position

scholarly journals Predicting in vivo binding sites of RNA-binding proteins using mRNA secondary structure

RNA ◽  
2010 ◽  
Vol 16 (6) ◽  
pp. 1096-1107 ◽  
Author(s):  
X. Li ◽  
G. Quon ◽  
H. D. Lipshitz ◽  
Q. Morris
Keyword(s):  
Secondary Structure ◽  
Binding Sites ◽  
Binding Proteins ◽  
Rna Binding ◽  
Rna Binding Proteins ◽  
Mrna Secondary Structure ◽  
In Vivo Binding

scholarly journals Comparison of in vitro and in vivo binding sites competition of Bacillus thuringiensis Cry1 proteins in two important maize pests

2021 ◽  
Author(s):  
Patricia Hernández‐Martínez ◽  
Eric C. Bretsnyder ◽  
James A. Baum ◽  
Jeff A. Haas ◽  
Graham P. Head ◽  
...  
Keyword(s):  
Bacillus Thuringiensis ◽  
Binding Sites ◽  
In Vivo Binding

scholarly journals A novel mode of capping protein-regulation by twinfilin

eLife ◽  
2018 ◽  
Vol 7 ◽  
Author(s):  
Adam B Johnston ◽  
Denise M Hilton ◽  
Patrick McConnell ◽  
Britney Johnson ◽  
Meghan T Harris ◽  
...  
Keyword(s):  
Cell Morphology ◽  
Binding Sites ◽  
Actin Filaments ◽  
Protein Regulation ◽  
Actin Assembly ◽  
Binding Partner ◽  
In Vivo Binding ◽  
Capping Protein

Cellular actin assembly is controlled at the barbed ends of actin filaments, where capping protein (CP) limits polymerization. Twinfilin is a conserved in vivo binding partner of CP, yet the significance of this interaction has remained a mystery. Here, we discover that the C-terminal tail of Twinfilin harbors a CP-interacting (CPI) motif, identifying it as a novel CPI-motif protein. Twinfilin and the CPI-motif protein CARMIL have overlapping binding sites on CP. Further, Twinfilin binds competitively with CARMIL to CP, protecting CP from barbed-end displacement by CARMIL. Twinfilin also accelerates dissociation of the CP inhibitor V-1, restoring CP to an active capping state. Knockdowns of Twinfilin and CP each cause similar defects in cell morphology, and elevated Twinfilin expression rescues defects caused by CARMIL hyperactivity. Together, these observations define Twinfilin as the first ‘pro-capping’ ligand of CP and lead us to propose important revisions to our understanding of the CP regulatory cycle.

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