scholarly journals Long-Term Passive Ureteral Dilatation with Double-J Stent: Possibly an Effective Treatment for Recurrent Renal Colic Caused by Papillary Renal Necrosis

2020 ◽  
Vol 6 (4) ◽  
pp. 526-529
Author(s):  
Braulio O. Manzo ◽  
Eduardo Tejeda ◽  
Ben. H. Chew ◽  
Pompeyo Alarcon ◽  
Edson Flores ◽  
...  
Keyword(s):  
Effective Treatment ◽  
Renal Colic ◽  
Double J Stent ◽  
Ureteral Dilatation ◽  
Renal Necrosis

scholarly journals Endo-sponge Assisted Early Surgical Closure of Ileal Pouch-anal Anastomotic Leakage Preserves Long-term Function: A Cohort Study

2019 ◽  
Vol 13 (12) ◽  
pp. 1537-1545
Author(s):  
Karin A Wasmann ◽  
Maud A Reijntjes ◽  
Merel E Stellingwerf ◽  
Cyriel Y Ponsioen ◽  
Christianne J Buskens ◽  
...  
Keyword(s):  
Cohort Study ◽  
Effective Treatment ◽  
Anastomotic Leakage ◽  
Ileal Pouch ◽  
Pelvic Sepsis ◽  
Surgical Closure ◽  
Pouch Failure ◽  
Pouch Function ◽  
And Control

Abstract Background and Aims Endo-sponge [Braun Medical] assisted early surgical closure [ESC] is an effective treatment to control pelvic sepsis after ileal pouch-anal anastomosis [IPAA] leakage, and became standard treatment in our centre from 2010 onwards. The aim of this cohort study was to assess the long-term pouch function of ulcerative colitis [UC] patients treated with ESC or conventional management [CM] for anastomotic leakage after IPAA. Methods Consecutive patients who underwent an IPAA for UC between 2002 and 2017 were included. Patients treated with ESC [2010–2017] or CM [2002–2009] for anastomotic leakage were compared with control patients without anastomotic leakage of the corresponding time period. Main endpoints were long-term pouch function on a 3-point scale and pouch failure, as measured with the validated pouch dysfunction score questionnaire. Results Some 280 of 334 patients [84%] returned the pouch dysfunction questionnaire, of whom 18 were treated with ESC and 22 with CM for anastomotic leakage. Control cohorts included 133 [2010–2017] and 107 patients [2002–2009]. Between ESC-treated patients and control patients, pouch function [p = 0.647] and pouch failure rates [0/18 versus 5/133, p >0.99] were similar. CM resulted in worse pouch function [p = 0.016] and a higher pouch failure rate [5/22 versus 5/107, p = 0.013] compared with control patients. Conclusions ESC, in contrast to CM, for IPAA leakage in UC patients is associated with preservation of pouch function and preclusion of pouch failure, probably due to early and effective treatment of pelvic sepsis.

scholarly journals Treatment of the Fluoroquinolone-Associated Disability: The Pathobiochemical Implications

2017 ◽  
Vol 2017 ◽  
pp. 1-15 ◽  
Author(s):  
Krzysztof Michalak ◽  
Aleksandra Sobolewska-Włodarczyk ◽  
Marcin Włodarczyk ◽  
Justyna Sobolewska ◽  
Piotr Woźniak ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Gene Expression ◽  
Enzyme Activity ◽  
Antibiotic Therapy ◽  
Effective Treatment ◽  
Social Problem ◽  
Fenton Reaction ◽  
Current Paper ◽  
Bivalent Cations

Long-term fluoroquinolone-associated disability (FQAD) after fluoroquinolone (FQ) antibiotic therapy appears in recent years as a significant medical and social problem, because patients suffer for many years after prescribed antimicrobial FQ treatment from tiredness, concentration problems, neuropathies, tendinopathies, and other symptoms. The knowledge about the molecular activity of FQs in the cells remains unclear in many details. The effective treatment of this chronic state remains difficult and not effective. The current paper reviews the pathobiochemical properties of FQs, hints the directions for further research, and reviews the research concerning the proposed treatment of patients. Based on the analysis of literature, the main directions of possible effective treatment of FQAD are proposed: (a) reduction of the oxidative stress, (b) restoring reduced mitochondrion potential ΔΨm, (c) supplementation of uni- and bivalent cations that are chelated by FQs and probably ineffectively transported to the cell (caution must be paid to Fe and Cu because they may generate Fenton reaction), (d) stimulating the mitochondrial proliferation, (e) removing FQs permanently accumulated in the cells (if this phenomenon takes place), and (f) regulating the disturbed gene expression and enzyme activity.

Anti-inflammatory agents for prophylaxis and flares

2016 ◽  
Author(s):  
Nicola Dalbeth
Keyword(s):  
Effective Treatment ◽  
Interleukin 1 ◽  
Safety Data ◽  
Acute Gout ◽  
Repeated Use ◽  
Anti Inflammatory ◽  
Concomitant Medications

Acute gout requires rapid, effective treatment. Colchicine, non-steroidal anti-inflammatories, and corticosteroids are all effective; the choice of agent is dictated by the patient’s co-morbidities and concomitant medications. Interleukin-1 inhibitors are effective, but the high cost precludes routine use, and long-term safety data for repeated use are lacking.

scholarly journals The use of lithium in mixed states

CNS Spectrums ◽  
2019 ◽  
Vol 25 (4) ◽  
pp. 449-451 ◽  
Author(s):  
Gabriele Sani ◽  
Andrea Fiorillo
Keyword(s):  
Effective Treatment ◽  
Acute Treatment ◽  
Mood Stabilizers ◽  
Affective States ◽  
Mixed States ◽  
Term Management

Lithium is a unique drug. In more than 60 years of observation, it showed its multiple important clinical properties in treating mania, stabilizing mood alterations, preventing suicide and protecting from neurodegeneration. It was also the most extensively studied drug in psychiatry. Nevertheless, it is generally underprescribed. Specifically, lithium is virtually not considered in the treatment of patients affected by mixed affective states. Lithium is not suggested for the acute treatment of mixed affective states and is considered to be less effective than other mood stabilizers in the long-term management of these patients. The main reason why lithium has no indication for mixed states is the “lack of evidence.” Actually, there are several reasons to consider lithium as an effective treatment in patients with mixed affective states.

scholarly journals Balloon dilation for the treatment of nasopharyngeal stenosis in seven cats

2017 ◽  
Vol 3 (2) ◽  
pp. 205511691772998
Author(s):  
Stefeny Z Pollack ◽  
Peter S Chapman ◽  
Alan Klag
Keyword(s):  
Effective Treatment ◽  
Medical Records ◽  
Balloon Dilation ◽  
Clinical Signs ◽  
Upper Airway ◽  
Short Term ◽  
Effective Treatment Option ◽  
Endoscopic Guidance ◽  
Ocular Discharge

Objectives The objective of this study was to evaluate the effectiveness of balloon dilation for the treatment of nasopharyngeal stenosis in cats. Methods The medical records of seven cats with nasopharyngeal stenosis treated with balloon dilation were reviewed. The most common presenting clinical signs included upper airway noise, sneezing, nasal and/or ocular discharge. All seven cats were confirmed to have nasopharyngeal stenosis via nasopharyngeal endoscopy and were treated with balloon dilation under endoscopic guidance. Results All seven cats had acceptable short-term control (median 14 days) of clinical signs after the procedure. Two of six cats had successful long-term control (median 34 days) of clinical signs after one balloon dilation and an additional 2/6 cats had acceptable long-term control of clinical signs after a second balloon dilation procedure. The most significant complication of balloon dilation was the recurrence of stenosis. Conclusions and relevance The findings of this study indicate that balloon dilation is a safe and effective treatment option for the relief of clinical signs associated with nasopharyngeal stenosis in cats. Multiple procedures may be necessary for the best chance of long-term success.

Peptide receptor radioligand therapy is an effective treatment for the long-term stabilization of malignant gastrinomas

Cancer ◽  
2010 ◽  
Vol 117 (7) ◽  
pp. 1377-1385 ◽  
Author(s):  
Simona Grozinsky-Glasberg ◽  
Dganit Barak ◽  
Merav Fraenkel ◽  
Martin A. Walter ◽  
Jan Müeller-Brand ◽  
...  
Keyword(s):  
Effective Treatment ◽  
Radioligand Therapy ◽  
Peptide Receptor

Five Questions about Group Therapy in Long-Term Schizophrenia

1999 ◽  
Vol 32 (4) ◽  
pp. 515-524 ◽  
Author(s):  
Jay Smith
Keyword(s):  
Group Therapy ◽  
Effective Treatment ◽  
Time Scale

Group therapy has been demonstrated to be an effective treatment for individuals with long-term schizophrenic illnesses. However, therapists must be aware of the particular characteristics of these patients and modify their expectations, techniques and time scale of treatment accordingly. If this can be achieved, both patient and therapist may be surprised by how rewarding and helpful such a group may become.

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