The Relationship Between Low-Frequency Motions and Community Structure of Residue Network in Protein Molecules

2018 ◽  
Vol 25 (1) ◽  
pp. 103-113 ◽  
Author(s):  
Weitao Sun
Keyword(s):  
Community Structure ◽  
Low Frequency ◽  
Protein Molecules ◽  
The Relationship

scholarly journals Low-frequency vibrations of helical structures in protein molecules

1983 ◽  
Vol 209 (3) ◽  
pp. 573-580 ◽  
Author(s):  
K C Chou
Keyword(s):  
Raman Spectra ◽  
Mechanism Of Action ◽  
Calculated Result ◽  
Low Frequency ◽  
Helical Structures ◽  
Low Frequency Vibration ◽  
Protein Molecules ◽  
The Relationship ◽  
Feasible Experiment

A physically intuitive and mathematically easily handled formula is presented for calculating the low-frequency vibrations of helical structures in protein molecules. alpha-Chymotrypsin is taken as an example, and the calculated result shows precise agreement with observations of the low-frequency Raman spectra. As reflected in the formula, this kind of low frequency is very sensitive to the conformation of a biomacromolecule, and can therefore serve as a vehicle to investigate the mechanism of action of a biomacromolecule from the viewpoint of dynamics. On this basis a feasible experiment is suggested by which one can examine the relationship between a presumed mode of low-frequency vibration in a biomacromolecule and its activity.

Practical High Resolution Microscopy

1968 ◽  
Vol 26 ◽  
pp. 302-303
Author(s):  
P. A. Marsh ◽  
T. Mullens ◽  
D. Price
Keyword(s):  
High Resolution ◽  
Magnetic Fields ◽  
Low Frequency ◽  
Resolving Power ◽  
Careful Attention ◽  
Electron Microscopes ◽  
The Relationship ◽  
High Resolution Microscopy ◽  
New Facilities

It is possible to exceed the guaranteed resolution on most electron microscopes by careful attention to microscope parameters essential for high resolution work. While our experience is related to a Philips EM-200, we hope that some of these comments will apply to all electron microscopes.The first considerations are vibration and magnetic fields. These are usually measured at the pre-installation survey and must be within specifications. It has been our experience, however, that these factors can be greatly influenced by the new facilities and therefore must be rechecked after the installation is completed. The relationship between the resolving power of an EM-200 and the maximum tolerable low frequency interference fields in milli-Oerstedt is 10 Å - 1.9, 8 Å - 1.4, 6 Å - 0.8.

scholarly journals Slithering CSF: Cerebrospinal Fluid Dynamics in the Stationary and Moving Viper Boa, Candoia aspera

Biology ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 672
Author(s):  
Bruce A. Young ◽  
Skye Greer ◽  
Michael Cramberg
Keyword(s):  
Cerebrospinal Fluid ◽  
Cardiac Cycle ◽  
Low Frequency ◽  
Mean Amplitude ◽  
The Body ◽  
Body Waves ◽  
Lower Amplitude ◽  
Lateral Undulation ◽  
Recovery From Anesthesia ◽  
The Relationship

In the viper boa (Candoia aspera), the cerebrospinal fluid (CSF) shows two stable overlapping patterns of pulsations: low-frequency (0.08 Hz) pulses with a mean amplitude of 4.1 mmHg that correspond to the ventilatory cycle, and higher-frequency (0.66 Hz) pulses with a mean amplitude of 1.2 mmHg that correspond to the cardiac cycle. Manual oscillations of anesthetized C. aspera induced propagating sinusoidal body waves. These waves resulted in a different pattern of CSF pulsations with frequencies corresponding to the displacement frequency of the body and with amplitudes greater than those of the cardiac or ventilatory cycles. After recovery from anesthesia, the snakes moved independently using lateral undulation and concertina locomotion. The episodes of lateral undulation produced similar influences on the CSF pressure as were observed during the manual oscillations, though the induced CSF pulsations were of lower amplitude during lateral undulation. No impact on the CSF was found while C. aspera was performing concertina locomotion. The relationship between the propagation of the body and the CSF pulsations suggests that the body movements produce an impulse on the spinal CSF.

scholarly journals On the Relationship between Regional Ocean Heat Content and Sea Surface Height

2017 ◽  
Vol 30 (22) ◽  
pp. 9195-9211 ◽  
Author(s):  
John T. Fasullo ◽  
Peter R. Gent
Keyword(s):  
Time Scales ◽  
Low Frequency ◽  
Heat Content ◽  
Sea Surface Height ◽  
Ocean Heat Content ◽  
Ocean Dynamics ◽  
Sea Surface ◽  
Altimeter Data ◽  
Model Control ◽  
The Relationship

Abstract An accurate diagnosis of ocean heat content (OHC) is essential for interpreting climate variability and change, as evidenced for example by the broad range of hypotheses that exists for explaining the recent hiatus in global mean surface warming. Potential insights are explored here by examining relationships between OHC and sea surface height (SSH) in observations and two recently available large ensembles of climate model simulations from the mid-twentieth century to 2100. It is found that in decadal-length observations and a model control simulation with constant forcing, strong ties between OHC and SSH exist, with little temporal or spatial complexity. Agreement is particularly strong on monthly to interannual time scales. In contrast, in forced transient warming simulations, important dependencies in the relationship exist as a function of region and time scale. Near Antarctica, low-frequency SSH variability is driven mainly by changes in the circumpolar current associated with intensified surface winds, leading to correlations between OHC and SSH that are weak and sometimes negative. In subtropical regions, and near other coastal boundaries, negative correlations are also evident on long time scales and are associated with the accumulated effects of changes in the water cycle and ocean dynamics that underlie complexity in the OHC relationship to SSH. Low-frequency variability in observations is found to exhibit similar negative correlations. Combined with altimeter data, these results provide evidence that SSH increases in the Indian and western Pacific Oceans during the hiatus are suggestive of substantial OHC increases. Methods for developing the applicability of altimetry as a constraint on OHC more generally are also discussed.

NEW ETIOLOGICAL FACTORS OF OCCUPATIONAL HEARING LOSS

2021 ◽  
Author(s):  
V.B. Pankova ◽  
◽  
М.F. Vilk ◽  
◽  
◽  
...  
Keyword(s):  
Hearing Loss ◽  
Low Frequency ◽  
Evidence Base ◽  
Frequency Noise ◽  
Labor Intensity ◽  
Etiological Factors ◽  
Hearing Organ ◽  
The Relationship ◽  
Vascular Stria ◽  
Occupational Hearing Loss

Annotation. On the example of railway and air transport, a number of new issues of occupational hearing loss are shown, requiring study and subsequent implementation in practical health care, as new etiological factors in the development of hearing loss. This concerns the factor of labor intensity, which has a potentiating, pathogenetic significance, along with noise, in the development of hearing loss due to the formation of chronic stress, leading to additional ischemia of the vascular stria and damage to the neuroepithelium of the inner ear. There is a need, along with the development of a methodology for assessing the factor of labor intensity for SOUT of workplaces, to determine the criteria for its negative action when used for the examination of the connection between the disease of the organ of hearing and the profession. In the «List of occupational diseases» in clause 2.4.2. indicated diseases associated with exposure to infrasound (IZ), among the manifestations of which, called sensorineural hearing loss bilateral. However, IZ, as well as low-frequency noise (LFN), were not previously considered as significant adverse factors in relation to the hearing organ in mass clinical trials, therefore, there are no expert criteria for the relationship between hearing loss and their impact, which could be applied in practice, which requires accumulation of evidence base for the subsequent substantiation of an independent nosological form of a disease of the organ of hearing, associated with mechanoacoustic exposure.

scholarly journals The Relationship between Vibratory Sensation and Body Surface Vibration Induced by Low-Frequency Noise

2002 ◽  
Vol 21 (2) ◽  
pp. 87-100 ◽  
Author(s):  
Yukio Takahashi ◽  
Kazuo Kanada ◽  
Yoshiharu Yonekawa
Keyword(s):  
Body Surface ◽  
Mechanical Vibration ◽  
Low Frequency ◽  
The Body ◽  
Frequency Noise ◽  
Low Frequency Noise ◽  
Vibration Acceleration ◽  
Surface Vibration ◽  
Human Body Surface ◽  
The Relationship

Human body surface vibration induced by low-frequency noise was measured at the forehead, the chest and the abdomen. At the same time, subjects rated their vibratory sensation at each of these locations. The relationship between the measured vibration on the body surface and the rated vibratory sensation was examined, revealing that the vibratory sensations perceived in the chest and abdomen correlated closely with the vibration acceleration levels of the body surface vibration. This suggested that a person exposed to low-frequency noise perceives vibration at the chest or abdomen by sensing the mechanical vibration that the noise induces in the body. At the head, on the other hand, it was found that the vibratory sensation correlated comparably with the vibration acceleration level of the body surface vibration and the sound pressure level of the noise stimulus. This finding suggested that the mechanism of perception of vibration in the head is different from that of the perception of vibratory sensation in the chest and the abdomen.

scholarly journals The relationship between S-wave reflectors and deep low-frequency earthquakes in the northern Kinki district, southwestern Japan

2018 ◽  
Vol 70 (1) ◽  
Author(s):  
Shinya Katoh ◽  
Yoshihisa Iio ◽  
Hiroshi Katao ◽  
Masayo Sawada ◽  
Kazuhide Tomisaka ◽  
...  
Keyword(s):  
Low Frequency ◽  
S Wave ◽  
The Relationship

scholarly journals Rare microbes from diverse Earth biomes dominate community activity

2019 ◽  
Author(s):  
Rohan Sachdeva ◽  
Barbara J. Campbell ◽  
John F. Heidelberg
Keyword(s):  
Community Structure ◽  
Microbial Activity ◽  
Ecosystem Function ◽  
Total Activity ◽  
Reaction Rates ◽  
Community Activity ◽  
Crucial Component ◽  
Tightly Coupled ◽  
The Relationship

AbstractMicrobes are the Earth’s most numerous organisms and are instrumental in driving major global biological and chemical processes. Microbial activity is a crucial component of all ecosystems, as microbes have the potential to control any major biochemical process. In recent years, considerable strides have been made in describing the community structure,i.e. diversity and abundance, of microbes from the Earth’s major biomes. In virtually all environments studied, a few highly abundant taxa dominate the structure of microbial communities. Still, microbial diversity is high and is concentrated in the less abundant, or rare, fractions of the community,i.e. the “long tail” of the abundance distribution. The relationship between microbial community structure and activity, specifically the role of rare microbes, and its connection to ecosystem function, is not fully understood. We analyzed 12.3 million metagenomic and metatranscriptomic sequence assemblies and their genes from environmental, human, and engineered microbiomes, and show that microbial activity is dominated by rare microbes (96% of total activity) across all measured biomes. Further, rare microbial activity was comprised of traits that are fundamental to ecosystem and organismal health,e.g. biogeochemical cycling and infectious disease. The activity of rare microbes was also tightly coupled to temperature, revealing a link between basic biological processes,e.g. reaction rates, and community activity. Our study provides a broadly applicable and predictable paradigm that implicates rare microbes as the main microbial drivers of ecosystem function and organismal health.

Trans*formative Thinking Through Sound: Artistic Research in Gender and Sound Beyond the Human

2021 ◽  
Vol 4 (1) ◽  
pp. 335-346
Author(s):  
Luca Soudant
Keyword(s):  
Queer Theory ◽  
Low Frequency ◽  
Sound Studies ◽  
Sound Design ◽  
Research Practice ◽  
Sound Waves ◽  
Frequency Sound ◽  
Gender Power ◽  
The Relationship ◽  
Artistic Research

Abstract This article reflects on an ongoing artistic research practice that deals with sound, gender, power, spatiality, and human–nonhuman entanglement. Sparked by a sound design for a less crunchy “lady-friendly” crisp, the research inquires the relationship between gender and sound at human–nonhuman encounter through making and thinking. Drawing on queer theory, sound studies, and posthumanism, it aims to transcend essentialist, vision-focused, and anthropocentric conceptualisations of gender and, as an insight gained from working with low-frequency sound waves, it reflects on sound as material-philosophically demonstrating human–nonhuman interconnectedness. The latter, as this article proposes, may encourage us to horizontalise hierarchies between the human and nonhuman. Finally, this text situates sonic thinking as a mode of trans*formative thinking: a process-oriented philosophy that aims to embrace the messy, queer ways of human–nonhuman relationality, which characterises a vibrant space from which this artistic research will further develop.

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