Diode Laser Radiation and Its Bactericidal Effect in Root Canal Wall Dentin

2000 ◽  
Vol 18 (2) ◽  
pp. 57-60 ◽  
Author(s):  
NORBERT GUTKNECHT ◽  
DIRK VAN GOGSWAARDT ◽  
GEORG CONRADS ◽  
CHRISTIAN APEL ◽  
CLAUS SCHUBERT ◽  
...  
2004 ◽  
Vol 22 (1) ◽  
pp. 9-13 ◽  
Author(s):  
N. Gutknecht ◽  
R. Franzen ◽  
M. Schippers ◽  
F. Lampert

2000 ◽  
Author(s):  
Norbert Gutknecht ◽  
Georg Conrads ◽  
Christian Apel ◽  
Claus Schubert ◽  
Friedrich Lampert

2018 ◽  
Vol 2 (4) ◽  
pp. 247-254 ◽  
Author(s):  
Norbert Gutknecht ◽  
Nour Al Hassan ◽  
Miguel R. Martins ◽  
Georg Conrads ◽  
Rene Franzen

2021 ◽  
Vol 22 (16) ◽  
pp. 8384
Author(s):  
Naoya Higuchi ◽  
Jun-ichiro Hayashi ◽  
Masanori Fujita ◽  
Yuki Iwamura ◽  
Yasuyuki Sasaki ◽  
...  

Apical periodontitis, an inflammatory lesion causing bone resorption around the apex of teeth, is treated by eradicating infectious bacteria from the root canal. However, it has a high recurrence rate and often requires retreatment. We investigated the bactericidal effect of antimicrobial photodynamic therapy (aPDT)/photodynamic antimicrobial chemotherapy (PACT) using indocyanine green (ICG)-loaded nanospheres coated with chitosan and a diode laser on a biofilm of Enterococcus faecalis, a pathogen of refractory apical periodontitis. Biofilm of E. faecalis was cultured in a porcine infected root canal model. ICG solution was injected into the root canal, which was then irradiated with a laser (810 nm wavelength) from outside the root canal. The bactericidal effect was evaluated by colony counts and scanning electron microscopy. The result of the colony counts showed a maximum 1.89 log reduction after irradiation at 2.1 W for 5 min. The temperature rise during aPDT/PACT was confirmed to be within a safe range. Furthermore, the light energy transmittance through the root was at a peak approximately 1 min after the start of irradiation, indicating that most of the ICG in the root canal was consumed. This study shows that aPDT/PACT can suppress E. faecalis in infected root canals with high efficiency.


LASER THERAPY ◽  
2014 ◽  
Vol 23 (4) ◽  
pp. 263-271 ◽  
Author(s):  
Ghanbari Habiboallah ◽  
Zakeri Mahdi ◽  
Naderi Nasab Mahbobeh ◽  
Zareian Jahromi Mina ◽  
Faghihi Sina ◽  
...  

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