Long-Term Results of Targeted Low-Grade Glioma Treatment with 213Bi-DOTA-[Thi8,Met(O2)11]-Substance P

2019 ◽  
Vol 34 (6) ◽  
pp. 413-416 ◽  
Author(s):  
Dominik Cordier ◽  
Adrian Merlo
2020 ◽  
Vol 22 (Supplement_3) ◽  
pp. iii367-iii367
Author(s):  
Nongnuch Sirachainan ◽  
Attaporn Boongerd ◽  
Samart Pakakasama ◽  
Usanarat Anurathapan ◽  
Ake Hansasuta ◽  
...  

Abstract INTRODUCTION Low grade glioma (LGG) is the most common central nervous system (CNS) tumor in children accounted for 30–50%. Regarding benign characteristic of disease, surgical management remains the mainstay of treatment. However, surgical approach is limited in some conditions such as location at brainstem or infiltrative tumor. Chemotherapy and radiation treatments have been included in order to control tumor progression. The 5-years survival rate is approach 90% especially in patients who receive complete resection. However, the outcome of children with LGG in low to middle income is limited. Therefore, the aim of the study was to determine long-term outcome of children with newly diagnosed LGG. METHODS A retrospective study enrolled children aged <18 years who were newly diagnosed LGG during January 2006- December 2019. Diagnosis of LGG was confirmed by histological findings of grade I and II according to WHO criteria. RESULTS A total of 40 patients, female to male ratio was 1:1.35 and mean (SD) for age was 6.7 (4.0) years. The most common location was optic chiasmatic pathway (42.5%), followed by suprasellar region (25.0%). Sixty percent of patients received at least partial tumor removal. Chemotherapy and radiation had been used in 70% and 10.0% respectively. The 10-year progression free survival was 74.1±11.4% and overall survival was 96.2±3.8%. SUMMARY: Treatment of Pediatric LGG mainly required surgical management, however, chemotherapy and radiation had been used in progressive disease. The outcome was excellent.


2009 ◽  
Vol 75 (5) ◽  
pp. 1401-1407 ◽  
Author(s):  
Glenn Bauman ◽  
Barbara Fisher ◽  
Christopher Watling ◽  
J. Gregory Cairncross ◽  
David Macdonald

Neurology ◽  
2001 ◽  
Vol 56 (10) ◽  
pp. 1285-1290 ◽  
Author(s):  
O. Surma-aho ◽  
M. Niemela ◽  
J. Vilkki ◽  
M. Kouri ◽  
A. Brander ◽  
...  

Cancer ◽  
2016 ◽  
Vol 122 (8) ◽  
pp. 1261-1269 ◽  
Author(s):  
Rahul Krishnatry ◽  
Nataliya Zhukova ◽  
Ana S. Guerreiro Stucklin ◽  
Jason D. Pole ◽  
Matthew Mistry ◽  
...  

Author(s):  
S. Tabrizi ◽  
B.Y. Yeap ◽  
J.C. Sherman ◽  
L.B. Nachtigall ◽  
M.K. Colvin ◽  
...  

2013 ◽  
Vol 15 (4) ◽  
pp. 469-479 ◽  
Author(s):  
S. Leu ◽  
S. von Felten ◽  
S. Frank ◽  
E. Vassella ◽  
I. Vajtai ◽  
...  

2012 ◽  
Vol 17 (3) ◽  
pp. 141-145 ◽  
Author(s):  
Anna Mucha-Małecka ◽  
Bogdan Gliński ◽  
Marcin Hetnał ◽  
Magdalena Jarosz ◽  
Jacek Urbański ◽  
...  

2011 ◽  
Vol 79 (4) ◽  
pp. 1131-1138 ◽  
Author(s):  
Rudolf Korinthenberg ◽  
Daniela Neuburger ◽  
Michael Trippel ◽  
Christoph Ostertag ◽  
Guido Nikkhah

2016 ◽  
pp. 44-48
Author(s):  
I. V. Mikhailov ◽  
T. N. Nesterovich ◽  
S. L. Achinovich ◽  
V. M. Bondarenko ◽  
V. A. Kudryashov

Objective : to carry out the comparative analysis of clinical and morphological pathologic factors and long-term results of surgical treatment of cancer of the pancreas head (CPH) depending on prior biliary drainage (PBD). Material and methods . 39 patients (group I) were performed single-step surgery, PBD was performed in 41 cases (group II) at a total bilirubin level of more than 200 umol/l. Results . The prevalence of cancer of the pancreas head in the surveyed groups did not differ, patients of groups I and II revealed low-grade ductal adenocarcinoma in 43 and 79 %, respectively (p = 0.003), the survival median was 14 and 13 months, 3-year survival rate was found in 28.9 ± 8.4 and 3.5 ± 3.4 %, 5-year - 19.3 ± 7.9 and 0 % (p = 0.04). Conclusion . It is advisable to expand the indications for single-step surgical treatment for CPH complicated by obstructive jaundice.


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