The Role of Kinase Signaling in Resistance to Bevacizumab Therapy for Glioblastoma Multiforme

2019 ◽  
Vol 34 (6) ◽  
pp. 345-354 ◽  
Author(s):  
Sara Ramezani ◽  
Nasim Vousooghi ◽  
Mohammad Taghi Joghataei ◽  
Shahrokh Yousefzadeh Chabok
Keyword(s):  
Glioblastoma Multiforme ◽  
Kinase Signaling

cAMP and Extracellular Signal-Regulated Kinase Signaling in Response to d-Amphetamine and Methylphenidate in the Prefrontal Cortex in Vivo: Role of β1-Adrenoceptors

2005 ◽  
Vol 68 (2) ◽  
pp. 421-429 ◽  
Author(s):  
Vincent Pascoli ◽  
Emmanuel Valjent ◽  
Anne-Gaëlle Corbillé ◽  
Jean-Christophe Corvol ◽  
Jean-Pol Tassin ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Kinase Signaling ◽  
Extracellular Signal Regulated Kinase ◽  
Extracellular Signal

scholarly journals Wiskott-Aldrich Syndrome Interacting Protein Deficiency Uncovers the Role of the Co-receptor CD19 as a Generic Hub for PI3 Kinase Signaling in B Cells

Immunity ◽  
2015 ◽  
Vol 43 (4) ◽  
pp. 660-673 ◽  
Author(s):  
Selina Jessica Keppler ◽  
Francesca Gasparrini ◽  
Marianne Burbage ◽  
Shweta Aggarwal ◽  
Bruno Frederico ◽  
...  
Keyword(s):  
B Cells ◽  
Pi3 Kinase ◽  
Protein Deficiency ◽  
Kinase Signaling ◽  
Interacting Protein ◽  
Wiskott Aldrich Syndrome

Deciphering the signaling pathways of cancer stem cells of glioblastoma multiforme: Role of Akt/mTOR and MAPK pathways

2011 ◽  
Vol 51 (1) ◽  
pp. 164-170 ◽  
Author(s):  
Meena Jhanwar-Uniyal ◽  
Ladislau Albert ◽  
Elise McKenna ◽  
Michael Karsy ◽  
Priya Rajdev ◽  
...  
Keyword(s):  
Stem Cells ◽  
Glioblastoma Multiforme ◽  
Cancer Stem Cells ◽  
Signaling Pathways ◽  
Mapk Pathways

scholarly journals Combining experiments and in silico modeling to infer the role of adhesion and proliferation on the collective dynamics of cells

2021 ◽  
Author(s):  
Hygor P. M. Melo ◽  
F. Raquel Maia ◽  
André S. Nunes ◽  
Rui L. Reis ◽  
Joaquim M. Oliveira ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Cell Adhesion ◽  
Glioblastoma Multiforme ◽  
In Silico ◽  
Relative Importance ◽  
Collective Dynamics ◽  
Surfaces And Interfaces ◽  
In Silico Modeling ◽  
Cell Cell

ABSTRACTThe collective dynamics of cells on surfaces and interfaces poses technological and theoretical challenges in the study of morphogenesis, tissue engineering, and cancer. Different mechanisms are at play, including, cell-cell adhesion, cell motility, and proliferation. However, the relative importance of each one is elusive. Here, experiments with a culture of glioblastoma multiforme cells on a substrate are combined with in silico modeling to infer the rate of each mechanism. By parametrizing these rates, the time-dependence of the spatial correlation observed experimentally is reproduced. The obtained results suggest a reduction in cell-cell adhesion with the density of cells. The reason for such reduction and possible implications for the collective dynamics of cancer cells are discussed.

Role of the p38 MAP-Kinase Signaling Pathway for Cx32 and Claudin-1 in the Rat Liver

2003 ◽  
Vol 10 (4-6) ◽  
pp. 437-443 ◽  
Author(s):  
Takashi Kojima ◽  
Toshinobu Yamamoto ◽  
Masaki Murata ◽  
Mengdong Lan ◽  
Ken-ichi Takano ◽  
...  
Keyword(s):  
Map Kinase ◽  
Signaling Pathway ◽  
Rat Liver ◽  
P38 Map Kinase ◽  
Kinase Signaling ◽  
Map Kinase Signaling ◽  
Kinase Signaling Pathway ◽  
Map Kinase Signaling Pathway
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