Letter to the Editor: Rapid Clozapine Concentration Increase Following Augmentation with Low-Dose Fluvoxamine in 12-Year-Old with Childhood Onset Schizophrenia

2021 ◽  
Author(s):  
Kaitlin Boyle ◽  
Susan Cornett ◽  
Adam Fijtman ◽  
Tyehimba Hunt-Harrison
Keyword(s):  
Low Dose ◽  
Concentration Increase ◽  
Childhood Onset ◽  
Clozapine Concentration ◽  
Letter To The Editor ◽  
Childhood Onset Schizophrenia

scholarly journals National record-linkage study of hospital admissions for schizophrenia in childhood and adolescence in England

2021 ◽  
Author(s):  
Olena Seminog ◽  
Uy Hoang ◽  
Michael Goldacre ◽  
Anthony James
Keyword(s):  
Hospital Admissions ◽  
Population Based ◽  
Linkage Study ◽  
Incidence Rates ◽  
Childhood And Adolescence ◽  
Childhood Onset ◽  
Affective Psychosis ◽  
Health Service Provision ◽  
Childhood Onset Schizophrenia ◽  
Icd 10

Abstract Background There is a lack of information on changes in hospital admission rates for childhood-onset schizophrenia (COS), or on patient characteristics, to inform clinical research and health service provision. Aims To report age- and sex-specific incidence rates of hospital admissions and day patient care for schizophrenia (ICD-10 F20) and non-affective psychosis (ICD-10 F20-29), by year of occurrence and age, in childhood and adolescence. Methods Population-based study using person-linked data for England (available 2001–2016); time-periods in single years and 4-year groups. Results Hospitalised incidence for schizophrenia increased with increasing age, from 0.03 (95% confidence interval (CI) 0.02–0.05) and 0.01 (0–0.01) per 100,000 in, respectively, males and females aged 5–12 years, to 3.67 (3.44–3.91) in males and 1.58 (1.43–1.75) in females aged 13–17 years. There was no gender difference in hospitalised incidence rates in children aged 5–12, but in 13–17 years old, there was a male excess. Rates for schizophrenia were stable over time in 5–12 years old. In ages 13–17, rates for schizophrenia decreased between 2001–2004 and 2013–2016 in males, from 6.65 (6.04–7.31) down to 1.40 (1.13–1.73), and in females from 2.42 (2.05–2.83) to 1.18 (0.92–1.48). The hospitalisation rates for schizophrenia and non-affective psychosis, combined, in 13–17 years old decreased in males from 14.20 (13.30–15.14) in 2001–2004 to 10.77 (9.97–11.60) in 2013–2016, but increased in females from 7.49 (6.83–8.20) to 10.16 (9.38–11.00). Conclusions The study confirms that childhood-onset schizophrenia is extremely rare, with only 32 cases identified over a 15-year period in the whole of England. The incidence of schizophrenia and non-affective psychosis increased substantially in adolescence; however, the marked reduction in the proportion of those diagnosed with schizophrenia in this age group suggests a possible change in diagnostic practice.

6.89 DEFINING SYMPTOM DIMENSIONS AND SUBTYPES IN CHILDHOOD-ONSET SCHIZOPHRENIA

2016 ◽  
Vol 55 (10) ◽  
pp. S233
Author(s):  
Kirsten E.S. Craddock ◽  
Xueping Zhou ◽  
Frances F. Loeb ◽  
Judith L. Rapoport ◽  
Dwight Dickinson
Keyword(s):  
Childhood Onset ◽  
Symptom Dimensions ◽  
Childhood Onset Schizophrenia

Superior temporal gyrus differences in childhood-onset schizophrenia

2005 ◽  
Vol 73 (2-3) ◽  
pp. 235-241 ◽  
Author(s):  
Janelle L. Taylor ◽  
Rebecca E. Blanton ◽  
Jennifer G. Levitt ◽  
Rochelle Caplan ◽  
Daniel Nobel ◽  
...  
Keyword(s):  
Superior Temporal Gyrus ◽  
Childhood Onset ◽  
Childhood Onset Schizophrenia

Frequency and Severity of Enlarged Cavum Septi Pellucidi in Childhood-Onset Schizophrenia

1998 ◽  
Vol 155 (8) ◽  
pp. 1074-1079 ◽  
Author(s):  
Peg C. Nopoulos ◽  
Jay N. Giedd ◽  
Nancy C. Andreasen ◽  
Judith L. Rapoport
Keyword(s):  
Childhood Onset ◽  
Cavum Septi Pellucidi ◽  
Childhood Onset Schizophrenia

scholarly journals 3.68 Missense Variants in the ATP1A3 and FXYD Gene Family are Associated With Childhood-Onset Schizophrenia

2018 ◽  
Vol 57 (10) ◽  
pp. S204
Author(s):  
Vladimir Ferrafiat ◽  
Boris Chaumette ◽  
Amirthagowri Ambalavanan ◽  
Priscille Gerardin ◽  
Claudine Laurent ◽  
...  
Keyword(s):  
Gene Family ◽  
Childhood Onset ◽  
Missense Variants ◽  
Childhood Onset Schizophrenia
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