Single-Dose Pharmacokinetics of HLD200, a Delayed-Release and Extended-Release Methylphenidate Formulation, in Healthy Adults and in Adolescents and Children with Attention-Deficit/Hyperactivity Disorder

Ann Childress; Shailly Mehrotra; Jogarao Gobburu; Angus McLean; Norberto J. DeSousa; Bev Incledon

doi:10.1089/cap.2017.0044

Single-Dose Pharmacokinetics of HLD200, a Delayed-Release and Extended-Release Methylphenidate Formulation, in Healthy Adults and in Adolescents and Children with Attention-Deficit/Hyperactivity Disorder

Journal of Child and Adolescent Psychopharmacology ◽

10.1089/cap.2017.0044 ◽

2018 ◽

Vol 28 (1) ◽

pp. 10-18 ◽

Cited By ~ 10

Author(s):

Ann Childress ◽

Shailly Mehrotra ◽

Jogarao Gobburu ◽

Angus McLean ◽

Norberto J. DeSousa ◽

...

Keyword(s):

Attention Deficit Hyperactivity Disorder ◽

Single Dose ◽

Attention Deficit ◽

Extended Release ◽

Healthy Adults ◽

Hyperactivity Disorder ◽

Delayed Release

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4.23 PIVOTAL PHASE 3 TRIAL EVALUATING THE EFFICACY AND SAFETY OF HLD200, A NOVEL DELAYED-RELEASE AND EXTENDED-RELEASE FORMULATION OF METHYLPHENIDATE, IN CHILDREN WITH ATTENTION-DEFICIT/HYPERACTIVITY DISORDER

Journal of the American Academy of Child & Adolescent Psychiatry ◽

10.1016/j.jaac.2016.09.218 ◽

2016 ◽

Vol 55 (10) ◽

pp. S170

Author(s):

Valerie K. Arnold ◽

Norberto J. DeSousa ◽

Bev Incledon ◽

Floyd R. Sallee ◽

Timothy E. Wilens ◽

...

Keyword(s):

Attention Deficit Hyperactivity Disorder ◽

Attention Deficit ◽

Extended Release ◽

Efficacy And Safety ◽

Phase 3 ◽

Pivotal Phase ◽

Release Formulation ◽

Extended Release Formulation ◽

Hyperactivity Disorder ◽

Delayed Release

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Model-Based Approach for Establishing the Predicted Clinical Response of a Delayed-Release and Extended-Release Methylphenidate for the Treatment of Attention-Deficit/Hyperactivity Disorder

Journal of Clinical Psychopharmacology ◽

10.1097/jcp.0000000000001222 ◽

2020 ◽

Vol 40 (4) ◽

pp. 350-358 ◽

Cited By ~ 1

Author(s):

Roberto Gomeni ◽

Marina Komolova ◽

Bev Incledon ◽

Stephen V. Faraone

Keyword(s):

Attention Deficit Hyperactivity Disorder ◽

Clinical Response ◽

Attention Deficit ◽

Extended Release ◽

Hyperactivity Disorder ◽

Model Based ◽

Delayed Release

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Effect of Delayed-Release and Extended-Release Methylphenidate on Caregiver Strain and Validation of Psychometric Properties of the Caregiver Strain Questionnaire: Results from a Phase 3 Trial in Children with Attention-Deficit/Hyperactivity Disorder

Journal of Child and Adolescent Psychopharmacology ◽

10.1089/cap.2020.0159 ◽

2021 ◽

Author(s):

Frank A. López ◽

Stephen V. Faraone ◽

Jeffrey H. Newcorn ◽

Helen A. Doll ◽

Stephanie Rhoten ◽

...

Keyword(s):

Attention Deficit Hyperactivity Disorder ◽

Psychometric Properties ◽

Attention Deficit ◽

Extended Release ◽

Caregiver Strain ◽

Phase 3 ◽

Hyperactivity Disorder ◽

Delayed Release

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Open-label, Single-dose Trial to Assess the Pharmacokinetics of Centanafadine Extended-release Capsules in Pediatric Subjects With Attention-deficit Hyperactivity Disorder

Case Medical Research ◽

10.31525/ct1-nct04081363 ◽

2019 ◽

Author(s):

Keyword(s):

Attention Deficit Hyperactivity Disorder ◽

Single Dose ◽

Attention Deficit ◽

Extended Release ◽

Open Label ◽

Hyperactivity Disorder ◽

Dose Trial

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6.49 PHARMACOKINETICS OF A NOVEL, EXTENDED-RELEASE FORMULATION OF METHYLPHENIDATE (PRC-063) IN ADOLESCENTS WITH ATTENTION-DEFICIT/HYPERACTIVITY DISORDER AND IN HEALTHY ADULTS AT STEADY STATE

Journal of the American Academy of Child & Adolescent Psychiatry ◽

10.1016/j.jaac.2016.09.368 ◽

2016 ◽

Vol 55 (10) ◽

pp. S219-S220 ◽

Cited By ~ 1

Author(s):

Declan Martin Quinn ◽

Twyla D. Bode ◽

Graeme Donnelly ◽

Joseph L. Reiz

Keyword(s):

Attention Deficit Hyperactivity Disorder ◽

Steady State ◽

Attention Deficit ◽

Extended Release ◽

Healthy Adults ◽

Release Formulation ◽

Extended Release Formulation ◽

Hyperactivity Disorder

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A Randomized, Double-Blind, Placebo-Controlled Study of HLD200, a Delayed-Release and Extended-Release Methylphenidate, in Children with Attention-Deficit/Hyperactivity Disorder: An Evaluation of Safety and Efficacy Throughout the Day and Across Settings

Journal of Child and Adolescent Psychopharmacology ◽

10.1089/cap.2019.0070 ◽

2020 ◽

Vol 30 (1) ◽

pp. 2-14 ◽

Cited By ~ 2

Author(s):

Ann C. Childress ◽

Andrew J. Cutler ◽

Andrea Marraffino ◽

Mary Ann McDonnell ◽

John M. Turnbow ◽

...

Keyword(s):

Attention Deficit Hyperactivity Disorder ◽

Attention Deficit ◽

Extended Release ◽

Controlled Study ◽

Double Blind ◽

Safety And Efficacy ◽

Double Blind Placebo ◽

Hyperactivity Disorder ◽

Delayed Release

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A Single-Dose, Single-Period Pharmacokinetic Assessment of an Extended-Release Orally Disintegrating Tablet of Methylphenidate in Children and Adolescents with Attention-Deficit/Hyperactivity Disorder

Journal of Child and Adolescent Psychopharmacology ◽

10.1089/cap.2015.0261 ◽

2016 ◽

Vol 26 (6) ◽

pp. 505-512 ◽

Cited By ~ 14

Author(s):

Ann Childress ◽

Jeffrey Newcorn ◽

Jeffrey G. Stark ◽

Russ McMahen ◽

Mark Tengler ◽

...

Keyword(s):

Attention Deficit Hyperactivity Disorder ◽

Single Dose ◽

Children And Adolescents ◽

Attention Deficit ◽

Extended Release ◽

Orally Disintegrating Tablet ◽

Hyperactivity Disorder ◽

Single Period ◽

Pharmacokinetic Assessment

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36.4 A Phase 3 Registration Trial of Delayed-Release and Extended-Release Methylphenidate (HLD200) in the Treatment of Early Morning Functioning Impairments in Children with Attention-Deficit/Hyperactivity Disorder

Journal of the American Academy of Child & Adolescent Psychiatry ◽

10.1016/j.jaac.2016.07.331 ◽

2016 ◽

Vol 55 (10) ◽

pp. S315

Author(s):

Steven R. Pliszka

Keyword(s):

Attention Deficit Hyperactivity Disorder ◽

Attention Deficit ◽

Extended Release ◽

Early Morning ◽

Phase 3 ◽

Hyperactivity Disorder ◽

Delayed Release ◽

Registration Trial

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Efficacy and Safety of HLD200, Delayed-Release and Extended-Release Methylphenidate, in Children with Attention-Deficit/Hyperactivity Disorder

Journal of Child and Adolescent Psychopharmacology ◽

10.1089/cap.2017.0084 ◽

2017 ◽

Vol 27 (6) ◽

pp. 474-482 ◽

Cited By ~ 13

Author(s):

Steven R. Pliszka ◽

Timothy E. Wilens ◽

Samantha Bostrom ◽

Valerie K. Arnold ◽

Andrea Marraffino ◽

...

Keyword(s):

Attention Deficit Hyperactivity Disorder ◽

Attention Deficit ◽

Extended Release ◽

Efficacy And Safety ◽

Hyperactivity Disorder ◽

Delayed Release

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Effectiveness of an extended release stimulant medication in treating preschool children with attention deficit hyperactivity disorder (The APS Study)

PsycEXTRA Dataset ◽

10.1037/e657832010-001 ◽

2010 ◽

Author(s):

John H. Fanton

Keyword(s):

Attention Deficit Hyperactivity Disorder ◽

Preschool Children ◽

Attention Deficit ◽

Extended Release ◽

Stimulant Medication ◽

Hyperactivity Disorder

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