Attitudes Toward Stimulant Treatment of Offspring of Adult Patients with Attention-Deficit/Hyperactivity Disorder

2017 ◽  
Vol 27 (5) ◽  
pp. 422-428
Author(s):  
Carlos Canela ◽  
Anna Buadze ◽  
Anish Dube ◽  
Dominique Eich ◽  
Michael Liebrenz
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Adult Patients ◽  
Stimulant Treatment ◽  
Hyperactivity Disorder

scholarly journals Systematic review of transdermal treatment options in attention-deficit/hyperactivity disorder: implications for use in adult patients

CNS Spectrums ◽  
2021 ◽  
pp. 1-13
Author(s):  
Christoph U. Correll ◽  
Brittney R. Starling ◽  
Michael Huss
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
English Language ◽  
Treatment Options ◽  
Adult Patients ◽  
Publication Date ◽  
Potential Cost ◽  
Hyperactivity Disorder ◽  
Related Quality ◽  
Treatment Safety

Abstract Background Adults with attention-deficit/hyperactivity disorder (ADHD) often face delays in diagnosis and remain untreated, despite significant negative impacts. To evaluate the safety and efficacy of transdermal treatment options in children, adolescents, and adults, a systematic literature review was conducted, with a focus on the implications of transdermal therapies for ADHD in adults. Methods A MEDLINE/Embase/BIOSIS/SCOPUS database search was conducted December 4, 2019, for English-language articles of interventional clinical trials using transdermal formulations for the treatment of ADHD without publication date limit. Assessed outcomes included efficacy, safety, adherence, abuse potential, cost efficacy, and health-related quality of life. Results Of 23 eligible publications, 18 were in children or adolescents (n = 1699; range 23-305), and 5 in adults (n = 274; range 14-90); all included methylphenidate transdermal system (MTS). All seven pediatric publications reporting change in ADHD symptomology from baseline reported a significant improvement with MTS treatment. Similarly, in three adult publications, ADHD symptoms improved significantly with MTS treatment. Safety findings in pediatric and adult studies were comparable; the most frequently reported treatment-emergent adverse events (TEAEs), namely, headache, decreased appetite, and insomnia, were reported in 13/16 (81%) of publications reporting specific TEAEs. MTS-related dermal reactions were mostly mild and transient. Discontinuation due to dermal reactions was reported in 10 studies (range 0%-7.1% [1 of 14 patients]). MTS compliance was high when assessed (97%-99%). Conclusions Transdermal therapies provide a useful treatment formulation for ADHD. Studies of MTS and other transdermal formulations, such as amphetamine, in adult patients are needed in this underserved population.

Forty years of methylphenidate treatment in Attention-Deficit/Hyperactivity Disorder

2002 ◽  
Vol 6 (1_suppl) ◽  
pp. 17-30 ◽  
Author(s):  
C. K. Conners
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Drug Effects ◽  
Long Term Effects ◽  
Stimulant Treatment ◽  
Hyperactivity Disorder ◽  
Subject Selection ◽  
Methodological Rigor ◽  
Adolescents And Adults ◽  
Core Symptoms

This paper reviews approximately 40 years of stimulant drug treatment of children with behavior and learning problems. These patients generally fall under the rubric of Attention-Deficit/Hyperactivity Disorder (ADHD), with core symptoms of hyperactivity, impulsivity, and inattention being the most studied and most robust of the targets for stimulant treatment. In addition, the drug effects on other targets, such as cognitive and academic function, are included. The largest selection of studies involves methylphenidate. Both qualitative studies and meta-analytic studies from major reviews are examined. Variations in the methodology of the reviews are described and some of the discrepancies in interpretation examined. Despite wide variations in subject selection, types of trials, degree of methodological rigor, and the decade in which the studies took place, the evidence is remarkably consistent. The overall results suggest significant clinical impact upon the core features of ADHD. More studies of long-term effects and special populations such as older adolescents and adults will be necessary, though existing evidence strongly supports similar findings as for the younger patients with a diagnosis of ADHD.

Early maladaptive schemas in adult patients with attention deficit hyperactivity disorder

2016 ◽  
Vol 9 (2) ◽  
pp. 101-111 ◽  
Author(s):  
Alexandra Philipsen ◽  
Alexandra P. Lam ◽  
Sigrid Breit ◽  
Caroline Lücke ◽  
Helge H. Müller ◽  
...  
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Adult Patients ◽  
Early Maladaptive Schemas ◽  
Maladaptive Schemas ◽  
Hyperactivity Disorder

Neural correlates of performance monitoring in adult patients with attention deficit hyperactivity disorder (ADHD)

2010 ◽  
Vol 11 (2-2) ◽  
pp. 457-464 ◽  
Author(s):  
Martin J. Herrmann ◽  
Kathrin Mader ◽  
Theresa Schreppel ◽  
Christian Jacob ◽  
Monika Heine ◽  
...  
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Attention Deficit ◽  
Performance Monitoring ◽  
Neural Correlates ◽  
Adult Patients ◽  
Hyperactivity Disorder
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