Long-Term Safety of Divalproex Sodium Extended-Release in Children and Adolescents with Bipolar I Disorder

2009 ◽  
Vol 19 (1) ◽  
pp. 83-89 ◽  
Author(s):  
Laura Redden ◽  
Melissa DelBello ◽  
Karen Dineen Wagner ◽  
Timothy E Wilens ◽  
Shishuka Malhotra ◽  
...  
Keyword(s):  
Children And Adolescents ◽  
Extended Release ◽  
Divalproex Sodium ◽  
Bipolar I Disorder

Initial Treatment of Bipolar I Disorder in Children and Adolescents

2018 ◽  
Author(s):  
Stephanie Ng ◽  
Andres Martin
Keyword(s):  
Children And Adolescents ◽  
Adolescent Psychiatry ◽  
Initial Treatment ◽  
Clinical Case ◽  
Child And Adolescent Psychiatry ◽  
Divalproex Sodium ◽  
Bipolar I Disorder ◽  
Study Intervention ◽  
Landmark Study

This chapter provides a summary of a landmark study in child and adolescent psychiatry. In medication-naïve children and adolescents with bipolar I disorder who have had a recent manic or mixed phase episode, should risperidone, lithium, or divalproex sodium be used for initial treatment? Also, for partial responders or nonresponders to the first medication, which agent should be added on or switched to? Starting with these questions, it describes the basics of the study, including funding, study location, who was studied, how many patients, study design, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.

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