scholarly journals Effects of Cannabidiol Chewing Gum on Perceived Pain and Well-Being of Irritable Bowel Syndrome Patients: A Placebo-Controlled Crossover Exploratory Intervention Study with Symptom-Driven Dosing

2021 ◽  
Author(s):  
Anne-Claire B. van Orten-Luiten ◽  
Nicole M. de Roos ◽  
Soumia Majait ◽  
Ben J.M. Witteman ◽  
Renger F. Witkamp
Keyword(s):  
Irritable Bowel Syndrome ◽  
Intervention Study ◽  
Well Being ◽  
Chewing Gum ◽  
Perceived Pain ◽  
Irritable Bowel

scholarly journals Efficacy of Lactobacillus paracasei HA-196 and Bifidobacterium longum R0175 in Alleviating Symptoms of Irritable Bowel Syndrome (IBS): A Randomized, Placebo-Controlled Study

Nutrients ◽  
2020 ◽  
Vol 12 (4) ◽  
pp. 1159 ◽  
Author(s):  
Erin D. Lewis ◽  
Joseph M. Antony ◽  
David C. Crowley ◽  
Amanda Piano ◽  
Renu Bhardwaj ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Irritable Bowel Syndrome ◽  
Bifidobacterium Longum ◽  
Well Being ◽  
Lactobacillus Paracasei ◽  
Controlled Study ◽  
Double Blind ◽  
Gi Symptoms ◽  
Irritable Bowel

Specific probiotic strains can alleviate the gastrointestinal (GI) symptoms and psychiatric comorbidities of irritable bowel syndrome (IBS). In this randomized, double-blind, placebo-controlled study, the efficacy of Lactobacillus paracasei HA-196 (L. paracasei) and Bifidobacterium longum R0175 (B. longum) in reducing the GI and psychological symptoms of IBS was evaluated in 251 adults with either constipation (IBS-C), diarrhea (IBS-D), or mixed-pattern (IBS-M). Following a 2-week run-in period, participants were randomized to one of three interventions: L. paracasei (n = 84), B. longum (n = 83) or placebo (n = 81). IBS symptoms, stool frequency and consistency and quality of life were assessed by questionnaires. The differences from baseline in the severity of IBS symptoms at 4 and 8 weeks were similar between groups. Participants in this study were classified, after randomization, into subtypes according to Rome III. Within the L. paracasei group, complete spontaneous and spontaneous bowel movement frequency increased in participants with IBS-C (n = 10) after 8 weeks of supplementation (both p < 0.05) and decreased in participants with IBS-D (n = 10, p = 0.013). Both L. paracasei and B. longum supplementation improved the quality of life in emotional well-being and social functioning compared with baseline (all p < 0.05). In conclusion, L. paracasei and B. longum may reduce GI symptom severity and improve the psychological well-being of individuals with certain IBS subtypes.

Bifidobacterium infantis M-63 improves mental health in victims with irritable bowel syndrome developed after a major flood disaster

2019 ◽  
Vol 10 (2) ◽  
pp. 111-120 ◽  
Author(s):  
Z.F. Ma ◽  
N. Yusof ◽  
N. Hamid ◽  
R.M. Lawenko ◽  
W.M.Z. Wan Mohammad ◽  
...  
Keyword(s):  
Mental Health ◽  
Irritable Bowel Syndrome ◽  
Bodily Pain ◽  
Depression Scale ◽  
Bacterial Overgrowth ◽  
Well Being ◽  
Bifidobacterium Infantis ◽  
Before And After ◽  
Irritable Bowel ◽  
Lower Ratio

Individuals in a community who developed irritable bowel syndrome (IBS) after major floods have significant mental health impairment. We aimed to determine if Bifidobacterium infantis M-63 was effective in improving symptoms, psychology and quality of life measures in flood-affected individuals with IBS and if the improvement was mediated by gut microbiota changes. Design was non-randomised, open-label, controlled before-and-after. Of 53 participants, 20 with IBS were given B. infantis M-63 (1×109 cfu/sachet/day) for three months and 33 were controls. IBS symptom severity scale, hospital anxiety and depression scale, SF-36 Questionnaire, hydrogen breath testing for small intestinal bacterial overgrowth and stools for 16S rRNA metagenomic analysis were performed before and after intervention. 11 of 20 who were given probiotics (M-63) and 20 of 33 controls completed study as per-protocol. Mental well-being was improved with M-63 vs controls for full analysis (P=0.03) and per-protocol (P=0.01) populations. Within-group differences were observed for anxiety and bodily pain (both P=0.04) in the M-63 per-protocol population. Lower ratio of Firmicutes/Bacteroidetes was observed with M-63 vs controls (P=0.01) and the lower ratio was correlated with higher post-intervention mental score (P=0.04). B. infantis M-63 is probably effective in improving mental health of victims who developed IBS after floods and this is maybe due to restoration of microbial balance and the gut-brain axis. However, our conclusion must be interpreted within the context of limited sample size. The study was retrospectively registered on 12 October 2017 and the Trial Registration Number (TRN) was NCT03318614.

Impact of differences in severity of irritable bowel syndrome (IBS) on patients' well being and resource use

2001 ◽  
Vol 120 (5) ◽  
pp. A406-A406 ◽  
Author(s):  
J RICCI ◽  
P JHINGRAN ◽  
W HARRIS ◽  
A ASGHARIAN ◽  
M MARKOWITZ ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Resource Use ◽  
Well Being ◽  
Irritable Bowel

An Empirical Study on Why Men and Women Deal with Stress Differently

2016 ◽  
Vol 11 (01) ◽  
Author(s):  
Naini Jain ◽  
Mohit Rastogi
Keyword(s):  
Irritable Bowel Syndrome ◽  
Strong Predictor ◽  
Well Being ◽  
Role Stress ◽  
Human Beings ◽  
Men And Women ◽  
Work Related ◽  
Sequence Of Events ◽  
Irritable Bowel ◽  
Psychological Demands

In today’s competitive and changing environment every company expects its employees to act for achieving goals so that it attains success in its venture. Such higher commitments may lead to stress. Stress can be defined as a person-environment relationship (Folkman, 1984; Lazarus, 1966). It is a process, a sequence of events that will lead to a particular end. Stress is the result of imbalance between the physical and psychological demands encountered and the response capability of the individuals, in case failure to meet he demands has important implications for the individuals (McGrath 1970). Stress is s strong predictor of various personal and work related outcomes. It is evident from history that Women are considered to be the caretakers of others. In the recent study Doctors observed a irritable bowel syndrome (IBS) in human beings out of which 80% of them are women (July 13 2011, Times of India). This is due to the fact that they often spend less time nurturing their own emotional and physical needs. Conflict between the demands and behaviors expected from the women in different roles is expressed in the form of role stress that negatively influences the well being of women and their performances in different working areas.

scholarly journals Who Gets Irritable Bowel Syndrome and Does Seeing a Gastroenterologist Affect Its Course?

2001 ◽  
Vol 15 (suppl b) ◽  
pp. 5B-7B
Author(s):  
Charles N Bernstein
Keyword(s):  
Health Care ◽  
Irritable Bowel Syndrome ◽  
Health Care Utilization ◽  
Well Being ◽  
Care Utilization ◽  
Office Visits ◽  
Utilization Patterns ◽  
Irritable Bowel ◽  
The Impact

A review of studies involving patients with irritable bowel syndrome is presented. This review looks at the impact of gastroenterology consultation on health care utilization patterns and the well-being of the patient when followed up over a two-year period. A structured gastroenterological consultation between the physician and patient may decrease the number of office visits for gastrointestinal- related problems.

scholarly journals The Relationship between Personality Characteristics and Psychological Well-Being in Patients with Irritable Bowel Syndrome: The Role of Mediator of Emotion Regulation

2019 ◽  
Author(s):  
Javad Khalatbari ◽  
Vahid Hemmati Sabet ◽  
Farinaz Tabibzadeh ◽  
Akbar Hemmati Sabet
Keyword(s):  
Irritable Bowel Syndrome ◽  
Personality Traits ◽  
Emotional Regulation ◽  
Well Being ◽  
Psychological Well Being ◽  
Mediating Role ◽  
Proposed Model ◽  
Irritable Bowel ◽  
The Relationship

Introduction: The purpose of the present study was to investigate the relationship between personality traits and psychological well-being in people with irritable bowel syndrome with mediating role of emotional regulation. Methods: Research method according to the applied purpose, and the data collection method was a descriptive correlation and a quantitative data type. The statistical population of this study was all the patients with irritable bowel syndrome referring to Danesh Gastrointestinal Clinic in Tehran in 1396. The sample size was 390 participants selected by calculate sample size in structural equations and using a sample purposive sampling method. In order to measure the variables, personality traits Neo Costa & McGary (1992), Psychological well-being Ryff (1989), and of emotional regulation Gross and John (2003) questionnaires were used. Evaluation of the proposed model was done using structural equation modeling and SPSS Inc., Chicago, IL; Version 18 as well as Amos. The reliability, convergent validity and divergent validity of the questionnaire, were investigated.  Moreover, path coefficients and software significance coefficients were used to examine the research hypotheses. Results: The results showed that the degree of appropriateness of the proposed model was appropriate to the components of the research; personality traits and psychological well-being were found to be correlated with the role of mediator of emotional regulation in the patients with irritable bowel syndrome (p <0.0001). Conclusion: This research confirms the relationship between personality traits and psychological well-being with the mediating role of emotional regulation in people with irritable bowel syndrome. Because of Numerous scientific evidence in the ontology of this syndrome, further study on emotional skills and related problems in people with irritable bowel syndrome are required.

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