scholarly journals Comparison of the Neurotoxic and Seizure-Inducing Effects of Synthetic and Endogenous Cannabinoids with Δ9-Tetrahydrocannabinol

2020 ◽  
Vol 5 (1) ◽  
pp. 32-41 ◽  
Author(s):  
Chris S. Breivogel ◽  
Jacob R. Wells ◽  
Amreen Jonas ◽  
Artik H. Mistry ◽  
Morgan L. Gravley ◽  
...  
Keyword(s):  
Endogenous Cannabinoids

Retrograde Modulation of Synaptic Transmission Mediated by Endogenous Cannabinoids

2004 ◽  
Vol 2 (1) ◽  
pp. 49-57 ◽  
Author(s):  
M. Kano ◽  
T. Ohno-Shosaku ◽  
T. Maejima ◽  
T. Yoshida ◽  
K. Hashimoto
Keyword(s):  
Synaptic Transmission ◽  
Endogenous Cannabinoids

scholarly journals Brain Levels of Prostaglandins, Endocannabinoids, and Related Lipids Are Affected by Mating Strategies

2013 ◽  
Vol 2013 ◽  
pp. 1-14 ◽  
Author(s):  
Jordyn M. Stuart ◽  
Jason J. Paris ◽  
Cheryl Frye ◽  
Heather B. Bradshaw
Keyword(s):  
Sexual Differentiation ◽  
Home Cage ◽  
Mating Strategies ◽  
Spectrometric Analysis ◽  
Tandem Mass ◽  
Reproductive Behaviors ◽  
Tandem Mass Spectrometric Analysis ◽  
Tandem Mass Spectrometric ◽  
Endogenous Cannabinoids ◽  
The Brain

Background. Endogenous cannabinoids (eCBs) are involved in the development and regulation of reproductive behaviors. Likewise, prostaglandins (PGs) drive sexual differentiation and initiation of ovulation. Here, we use lipidomics strategies to test the hypotheses that mating immediately activates the biosynthesis and/or metabolism of eCBs and PGs and that specific mating strategies differentially regulate these lipids in the brain.Methods. Lipid extractions and tandem mass spectrometric analysis were performed on brains from proestrous rats that had experienced one of two mating strategies (paced or standard mating) and two nonmated groups (chamber exposed and home cage controls). Levels of PGs (PGE2 and PGF2alpha), eCBs (AEA and 2-AG,N-arachidonoyl glycine), and 4 related lipids (4N-acylethanolamides) were measured in olfactory bulb, hypothalamus, hippocampus, thalamus, striatum, midbrain, cerebellum, and brainstem.Results. Overall, levels of these lipids were significantly lower among paced compared to standard mated rats with the most dramatic decreases observed in brainstem, hippocampus, midbrain, and striatum. However, chamber exposed rats had significantly higher levels of these lipids compared to home cage controls and paced mated wherein the hippocampus showed the largest increases.Conclusions. These data demonstrate that mating strategies and exposure to mating arenas influence lipid signaling in the brain.

Endogenous cannabinoids contribute to remote ischemic preconditioning via cannabinoid CB2 receptors in the rat heart

2008 ◽  
Vol 579 (1-3) ◽  
pp. 246-252 ◽  
Author(s):  
Amir Reza Hajrasouliha ◽  
Sina Tavakoli ◽  
Mehdi Ghasemi ◽  
Pejman Jabehdar-Maralani ◽  
Hamed Sadeghipour ◽  
...  
Keyword(s):  
Ischemic Preconditioning ◽  
Rat Heart ◽  
Remote Ischemic Preconditioning ◽  
Cb2 Receptors ◽  
Endogenous Cannabinoids ◽  
Cannabinoid Cb2 Receptors

scholarly journals Retrograde signaling at central synapses via endogenous cannabinoids

2002 ◽  
Vol 7 (3) ◽  
pp. 234-235 ◽  
Author(s):  
M Kano ◽  
T Ohno-Shosaku ◽  
T Maejima
Keyword(s):  
Retrograde Signaling ◽  
Endogenous Cannabinoids ◽  
Central Synapses

scholarly journals Attenuation of Experimental Autoimmune Hepatitis by Exogenous and Endogenous Cannabinoids: Involvement of Regulatory T Cells

2008 ◽  
Vol 74 (1) ◽  
pp. 20-33 ◽  
Author(s):  
Venkatesh L. Hegde ◽  
Shweta Hegde ◽  
Benjamin F. Cravatt ◽  
Lorne J. Hofseth ◽  
Mitzi Nagarkatti ◽  
...  
Keyword(s):  
T Cells ◽  
Regulatory T Cells ◽  
Autoimmune Hepatitis ◽  
Endogenous Cannabinoids ◽  
Experimental Autoimmune

Exogenous Delta9-Tetrahydrocannabinol Influences Circulating Endogenous Cannabinoids in Humans

2013 ◽  
Vol 33 (5) ◽  
pp. 699-705 ◽  
Author(s):  
Carmen Walter ◽  
Nerea Ferreirós ◽  
Philipp Bishay ◽  
Gerd Geisslinger ◽  
Irmgard Tegeder ◽  
...  
Keyword(s):  
Endogenous Cannabinoids
Sign in / Sign up

Export Citation Format

Share Document