Bipolar Disorder and Gender Are Associated with Frontolimbic and Basal Ganglia Dysconnectivity: A Study of Topological Variance Using Network Analysis

2019 ◽  
Vol 9 (10) ◽  
pp. 745-759 ◽  
Author(s):  
Leila Nabulsi ◽  
Genevieve McPhilemy ◽  
Liam Kilmartin ◽  
Denis O'Hora ◽  
Stefani O'Donoghue ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Basal Ganglia ◽  
Network Analysis ◽  
And Gender

Quetiapine responsive catatonia in an autistic patient with comorbid bipolar disorder and idiopathic basal ganglia calcification

2014 ◽  
Vol 36 (9) ◽  
pp. 823-825 ◽  
Author(s):  
Makoto Ishitobi ◽  
Masao Kawatani ◽  
Mizuki Asano ◽  
Hirotaka Kosaka ◽  
Takashi Goto ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Basal Ganglia ◽  
Basal Ganglia Calcification ◽  
Autistic Patient ◽  
Idiopathic Basal Ganglia Calcification

342. Anatomical MRI study of basal ganglia in bipolar disorder patients

2000 ◽  
Vol 47 (8) ◽  
pp. S103
Author(s):  
P. Brambilla ◽  
K. Harenski ◽  
M. Nicoletti ◽  
A.G. Mallinger ◽  
E. Frank ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Basal Ganglia ◽  
Mri Study ◽  
Anatomical Mri

A-85 Differences in Cerebral Blood Perfusion with Individuals Diagnosed with Cluster B Personality Disorders

2021 ◽  
Vol 36 (6) ◽  
pp. 1132-1132
Author(s):  
D'anna Sydow ◽  
Daniel Amen ◽  
Kristen Willeumier ◽  
Brittny Arias ◽  
Charles J Golden ◽  
...  
Keyword(s):  
Blood Flow ◽  
Basal Ganglia ◽  
Personality Disorders ◽  
Limbic System ◽  
Negative Emotion ◽  
Blood Perfusion ◽  
Healthy Controls ◽  
Self Recognition ◽  
Cluster B Personality Disorders ◽  
And Gender

Abstract Objective To identify regional cerebral blood flow (rCBF) differences between individuals with DSM-IV diagnosis of Cluster B Personality Disorders (PDB) and healthy controls. Method Healthy controls (n = 81, Mage = 41.9, 53.0% female, 42.0% Caucasian) and persons diagnosed by psychiatric examination with PDB (n=, Mage = 34.12, 71.5% female, 69.8% Caucasian) were selected from a deidentified adult clinical outpatient database. Those with comorbid diagnoses were included. Significant differences (alpha = 0.005) were found for age [t(195) = −3.62], gender [χ2(2) = 7.1], and race [χ2(12) = 23.82] between groups. Mean age [t(523) = 2.09, p = 0.037) and gender [t(532) = −2.653, p = 0.008] different significantly between groups. No significant mean difference was found for education [t(523) = 0.832, p = 0.406]. Results Significant rCBF differences were noted in the cerebellum [left:F(1,192) = 10.5; right:F(1,192) = 4.6], limbic system [left:F(1,192) = 7.8; right:F(1,192) = 5.0], and basal ganglia [left:F(1,192) = 12.3; right:F(1,192) = 6.7]. Group means comparisons indicated higher perfusion in the cerebellum for the PDB group. Lower perfusion was found in the limbic system and basal ganglia in the PDB group. Conclusion Results observed in this study are concurrent with previous literature. PDB demonstrates higher activity in the cerebellum which contains inhibitory neurotransmitters, like Purkinje cells. The increased blood flow to cerebellar circuits may be related to the explicit self-recognition of negative emotion reported in PDB. Hypoperfusion found in the limbic system could be linked to impaired emotional responses. Apathy experienced in PDB may be accounted for by the low perfusion in the highly dopaminergic pathway in the basal ganglia. Further research should assess how different comorbidities with PDB affect perfusion.

scholarly journals Patterns of Multimorbidity in Adults: An Association Rules Analysis Using the Korea Health Panel

2020 ◽  
Vol 17 (8) ◽  
pp. 2618 ◽  
Author(s):  
Yoonju Lee ◽  
Heejin Kim ◽  
Hyesun Jeong ◽  
Yunhwan Noh
Keyword(s):  
Network Analysis ◽  
Chronic Conditions ◽  
Integrated Approach ◽  
Classification Of Diseases ◽  
Standard Classification ◽  
And Gender ◽  
Gender Groups ◽  
Association Rules Analysis ◽  
Different Characteristics ◽  
Public Health Practitioners

This study aimed to identify the prevalence and patterns of multimorbidity among Korean adults. A descriptive study design was used. Of 11,232 adults aged 18 and older extracted from the 2014 Korean Health Panel Survey, 7118 had one or more chronic conditions. The chronic conditions code uses the Korean Standard Classification of Diseases. Association rule analysis and network analysis were conducted to identify patterns of multimorbidity among 4922 participants with multimorbidity. The prevalence of multimorbidity in the overall population was 34.8%, with a higher prevalence among women (40.8%) than men (28.6%). Hypertension had the highest prevalence in both men and women. In men, diabetes mellitus and hypertension yielded the highest probability of comorbidity (10.04%). In women, polyarthrosis and hypertension yielded the highest probability of comorbidity (12.51%). The results of the network analysis in four groups divided according to gender and age showed different characteristics for each group. Public health practitioners should adopt an integrated approach to manage multimorbidity rather than an individual disease-specific approach, along with different strategies according to age and gender groups.

1473 – Seasonal pattern in bipolar disorder: prevalence, clinical characteristics and gender influence

2013 ◽  
Vol 28 ◽  
pp. 1 ◽  
Author(s):  
P.A. Geoffroy ◽  
B. Etain ◽  
J. Scott ◽  
C. Boudebesse ◽  
M. Lajnef ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Clinical Characteristics ◽  
Seasonal Pattern ◽  
Gender Influence ◽  
And Gender

scholarly journals Reduced intracellular pH in the basal ganglia and whole brain measured by 31P-MRS in bipolar disorder

2004 ◽  
Vol 58 (1) ◽  
pp. 82-88 ◽  
Author(s):  
HIROSHI HAMAKAWA ◽  
JUN MURASHITA ◽  
NAOTO YAMADA ◽  
TOSHIRO INUBUSHI ◽  
NOBUMASA KATO ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Basal Ganglia ◽  
Intracellular Ph ◽  
Whole Brain ◽  
31P Mrs

Evaluation of basal ganglia, brainstem raphe and ventricles in bipolar disorder by transcranial sonography

2011 ◽  
Vol 194 (2) ◽  
pp. 190-197 ◽  
Author(s):  
Christos Krogias ◽  
Kija Hoffmann ◽  
Jens Eyding ◽  
Dirk Scheele ◽  
Christine Norra ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Basal Ganglia ◽  
Transcranial Sonography ◽  
Brainstem Raphe

scholarly journals Late Onset Bipolar Disorder due to a Lacunar State

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Elena Antelmi ◽  
Margherita Fabbri ◽  
Lucia Cretella ◽  
Maria Guarino ◽  
Andrea Stracciari
Keyword(s):  
Bipolar Disorder ◽  
Basal Ganglia ◽  
Psychiatric Symptoms ◽  
Late Onset ◽  
Type Ii ◽  
Psychiatric Consultation ◽  
Limb Weakness ◽  
Recent Onset ◽  
New Onset

Objective.To describe a patient with a new onset bipolar disorder (BD) type II, secondary to a lacunar state.Background.Poststroke BD is rare and mainly associated with lesion in the prefrontal-striatal-thalamic circuit.Materials and Methods.A 51-year-old woman came to our attention for a mood disorder of recent onset. At 49, she had suffered acute left-sided limb weakness that improved spontaneously four days later. Arterial hypertension was subsequently diagnosed. After 6 months, she began to suffer from alternating brief periods of expansive and elevated mood with longer periods of depressed mood, with a suicide attempt. We performed extensive laboratory and instrumental investigations, as well as, psychiatric consultation, and a cognitive assessment, which was repeated 9 months later.Results.Brain magnetic resonance disclosed leukoaraiosis and a lacunar state of the basal ganglia. Transcranial Doppler showed a patent foramen ovale. A psychiatric consultation led to the diagnosis of BP type II. Neuropsychological evaluation detected deficits in attention/executive functions, verbal fluency, and memory. Nine months later, after specific psychiatric therapy, the psychiatric symptoms were remarkably improved.Conclusion.Our case sheds light on the role of the basal ganglia in mood disorders and the importance of ruling out brain injury in late onset BP.

scholarly journals Bipolar Disorder with Seasonal Pattern: Clinical Characteristics and Gender Influences

2013 ◽  
Vol 30 (9) ◽  
pp. 1101-1107 ◽  
Author(s):  
Pierre Alexis Geoffroy ◽  
Frank Bellivier ◽  
Jan Scott ◽  
Carole Boudebesse ◽  
Mohamed Lajnef ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Clinical Characteristics ◽  
Seasonal Pattern ◽  
And Gender ◽  
Gender Influences
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