European Regulations for Consumption of Cloned Animals and First-Generation Offspring Still Unwritten

2011 ◽  
Vol 30 (4) ◽  
pp. 469-469
Keyword(s):  
First Generation ◽  
European Regulations ◽  
Generation Offspring

scholarly journals Reproductive performance of the Antarctic tardigrades, Acutuncus antarcticus (Eutardigrada: Hypsibiidae), revived after being frozen for over 30 years and of their offspring

2019 ◽  
Vol 188 (3) ◽  
pp. 839-847
Author(s):  
Megumu Tsujimoto ◽  
Hiroshi Kagoshima ◽  
Hiroshi Kanda ◽  
Kenichi Watanabe ◽  
Satoshi Imura
Keyword(s):  
Reproductive Performance ◽  
First Generation ◽  
Dna Analysis ◽  
Term Survival ◽  
Long Term Survival ◽  
Genetic Types ◽  
Genetic Sequences ◽  
The Antarctic ◽  
Generation Offspring

Abstract Studies on the long-term survival of animals often focus on the specific instance of survival of animals only, and descriptions of subsequent reproduction are generally not reported. In this study, we recorded the reproductive performance of the first-generation offspring of the resuscitated individual (SB-1) and the hatchling of the resuscitated egg (SB-3) of the Antarctic tardigrade, Acutuncus antarcticus, after being frozen for 30.5 years. By providing further detailed description of the reproduction of SB-1 and SB-3 after revival, and then comparing the reproductive performance with that of their first-generation offspring, the possible indications of the damage accrued during the long-term preservation in SB-1 and SB-3 were more specifically detected. Additionally, the DNA analysis revealed two distinctively different mitochondrial genetic sequences of A. antarcticus between the SB strains and the LSW strain. The observed differences in some of the reproductive parameters between the two genetic types suggested a possible relationship between the life-history traits and genetic type in the species A. antarcticus. Further experiments using the SB-1 and SB-3 strains reared for a long period to exclude the instant effect of preservation are expected to improve our understanding of the mechanisms underlying the long-term survival of animals.

Relationship of Body Weight and Physical Activity with Aging Inbred Mice and First Generation Offspring

2008 ◽  
Vol 40 (Supplement) ◽  
pp. S326
Author(s):  
Michael J. Turner ◽  
Elizabeth Grindstaff ◽  
Sean M. Courtney ◽  
Ala'a El Masri ◽  
Steven R. Kleeberger ◽  
...  
Keyword(s):  
Physical Activity ◽  
Body Weight ◽  
First Generation ◽  
Inbred Mice ◽  
Relationship Of ◽  
Generation Offspring

scholarly journals Minireview: Transgenerational Inheritance of the Stress Response: A New Frontier in Stress Research

Endocrinology ◽  
2010 ◽  
Vol 151 (1) ◽  
pp. 7-13 ◽  
Author(s):  
Stephen G. Matthews ◽  
David I. W. Phillips
Keyword(s):  
Stress Response ◽  
First Generation ◽  
Intervention Strategies ◽  
Stress Axis ◽  
Biological Processes ◽  
Transgenerational Inheritance ◽  
Transgenerational Transmission ◽  
New Frontier ◽  
Stress Responsiveness ◽  
Generation Offspring

Abstract It is well established in animal models that the prenatal environment can have a major impact on stress axis function throughout life. These changes can predispose to various metabolic, cardiovascular, and neurobiological pathophysiologies. Emerging evidence indicates that the same programming effects occur in humans. It is now becoming clear that the pathophysiological effects are not confined to the first-generation offspring and that there is transgenerational memory of fetal experience that can extend across multiple generations. The complex mechanisms by which transgenerational transmission of stress responsiveness occur are rapidly becoming a focus of investigation. Understanding these fundamental biological processes will allow for development of intervention strategies that prevent or reverse adverse programming of the stress response.

scholarly journals HEMATOLOGICAL PARAMETERS OF RATS - WISTAR LINE UNDER THE BLV EXPERIMENTAL INFECTION

2018 ◽  
pp. 138-145
Author(s):  
E. S. Krasnikova ◽  
A. V. Krasnikov ◽  
R. V. Radionov ◽  
A. S. Belyakova ◽  
V. I. Okolelov
Keyword(s):  
First Generation ◽  
Hematological Parameters ◽  
Lymphocytic Leukemia ◽  
Laboratory Model ◽  
Transplacental Transmission ◽  
Average Volume ◽  
Initial Stage ◽  
Good Laboratory ◽  
Leukemia Development ◽  
Generation Offspring

Rats Wistar line were found to be a good laboratory model for the BLV infection pathogenesis studying. At the initial stage of infection, the rats’ first generation offspring were born healthy and colostral immunity protected them from infection for at least a month. Transplacental transmission of the virus to the rats’ second generation offspring was established in 30-33 % of experimental animals. The results of hematological studies have shown that in animals of experimental groups, thrombocytosis progressed over time and the average volume of platelets increased, which may be evidence of the megakaryocytic leukemia development. In some cases, there were signs of allergy, hemolytic anemia, lymphocytic leukemia. The most significant changes were found in the offspring of experimental rats.

scholarly journals Programmed aortic dysfunction and reduced Na+,K+-ATPase activity present in first generation offspring of lard-fed rats does not persist to the second generation

2007 ◽  
Vol 92 (3) ◽  
pp. 583-589 ◽  
Author(s):  
James A. Armitage ◽  
Asuka Ishibashi ◽  
Aswini A. Balachandran ◽  
Runa I. Jensen ◽  
Lucilla Poston ◽  
...  
Keyword(s):  
Atpase Activity ◽  
First Generation ◽  
Second Generation ◽  
Generation Offspring

Lifespan and autopsy findings in the first-generation offspring of X-irradiated male mice

1993 ◽  
Vol 319 (1) ◽  
pp. 71-79 ◽  
Author(s):  
G.E. Cosgrove ◽  
P.B. Selby ◽  
A.C. Upton ◽  
T.J. Mitchell ◽  
M.H. Steele ◽  
...  
Keyword(s):  
First Generation ◽  
Male Mice ◽  
Autopsy Findings ◽  
Generation Offspring
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