scholarly journals Acceptable Weight Ranges for Research Tissue Procurement and Biorepositories, 2015–2017

2018 ◽  
Vol 16 (6) ◽  
pp. 463-466
Author(s):  
David G. Nohle ◽  
Randal L. Mandt ◽  
Marta E. Couce ◽  
Anil V. Parwani ◽  
Leona W. Ayers
Keyword(s):  
Tissue Procurement

Using Biomedical Ethics Model to Explore Use of Postmortem Specimens in Tissue Research

2016 ◽  
Vol 3 (1) ◽  
pp. 234-237
Author(s):  
Stacy A. Drake ◽  
Erica T. Yu
Keyword(s):  
Ethical Issues ◽  
Biomedical Ethics ◽  
Human Tissues ◽  
Next Of Kin ◽  
Policy Makers ◽  
Institutional Review ◽  
Tissue Procurement ◽  
Tissue Research ◽  
Death Investigation ◽  
Medicolegal Death Investigation

Researchers often have a need to conduct human tissue research using postmortem specimens. Medicolegal death investigation organizations are untapped areas for obtaining postmortem human tissues. Because death investigation organizations are not required by law to conduct or support research, an ethical dilemma exists in whether or not researchers should use cadaver tissues for research purposes. This paper analyzes the ethical issues of using human tissues through discussion of principles of biomedical ethics, respect for autonomy, nonmaleficence, beneficence, and justice. Policy makers, organ and tissue procurement organizations, medicolegal death investigation organizations, and scientists should be aware of these principles when considering researchers requests. The authors conclude that with Institutional Review Board approval and next of kin consent, there are prevailing reasons for using postmortem tissue for research.

Unexpected Neoplasia in Autopsies: Potential Implications for Tissue and Organ Safety

2009 ◽  
Vol 133 (12) ◽  
pp. 1923-1931 ◽  
Author(s):  
Mary Ann Sens ◽  
Xu Dong Zhou ◽  
Timothy Weiland ◽  
A. Marvin Cooley
Keyword(s):  
Lymphoblastic Leukemia ◽  
Forensic Autopsy ◽  
Medical Examiner ◽  
Minimal Risk ◽  
Neoplastic Tissue ◽  
Donor Pool ◽  
Potential Donor ◽  
Tissue Donor ◽  
Medical Evaluation ◽  
Tissue Procurement

Abstract Context.—Medical examiner cases are increasingly used as tissue donor referral sources to meet the ever-growing need for transplant tissues. The assumption is often made that traumatic and sudden deaths have minimal risk of unsuspected neoplasia. An autopsy of a registered tissue donor with strong preautopsy clinical assessment of a saddle pulmonary embolus revealed unsuspected acute lymphoblastic leukemia, prompting a review of the incidence of unsuspected neoplasia from a regional forensic autopsy practice. Objective.—To determine the incidence of (1) unsuspected neoplasia, (2) clinical concordance of known neoplasia, and (3) potential donor referral in a regional forensic autopsy service. Design.—A retrospective, 5-year review of 412 autopsies from a regional, primarily forensic, autopsy service to determine the incidence of unsuspected neoplasia, clinical concordance of known neoplasia, and the preautopsy assessment of potential donor referral suitability. Results.—Unsuspected neoplasia rate at autopsy was 7% (29 of 412 patients); cancer was the cause of death in 41% (12 of 29 patients) of these individuals. In patients with a history of cancer, the discordance of cancer diagnosis was 44% (4 of 9 patients [11 patients with known cancer, 2 who refused medical evaluation were excluded from the study]). Nearly 60% (17 of 29 patients) of the unsuspected cancer cases had no apparent reason for deferral of tissue procurement before the autopsy examination. Conclusions.—The 7% incidence of unsuspected cancer in a forensic autopsy practice raises concern for the potential introduction of neoplastic tissue in the donor pool. To ensure the safety of this vital resource, mandatory complete autopsies on deceased donors are advocated as well as a tissue-recipient registry to track donor-related neoplasia.

scholarly journals Experience of nurses in the process of donation of organs and tissues for transplant

2014 ◽  
Vol 22 (2) ◽  
pp. 226-233 ◽  
Author(s):  
Edvaldo Leal de Moraes ◽  
Marcelo José dos Santos ◽  
Miriam Aparecida Barbosa Merighi ◽  
Maria Cristina Komatsu Braga Massarollo
Keyword(s):  
Qualitative Study ◽  
Healthcare Professionals ◽  
Phenomenological Approach ◽  
Individual Interviews ◽  
Donation Process ◽  
Tissue Procurement ◽  
The City

OBJECTIVE: to investigate the meaning of the action of nurses in the donation process to maintain the viability of organs and tissues for transplantation.METHOD: this qualitative study with a social phenomenological approach was conducted through individual interviews with ten nurses of three Organ and Tissue Procurement Services of the city of São Paulo.RESULTS: the experience of the nurses in the donation process was represented by the categories: obstacles experienced in the donation process, and interventions performed. The meaning of the action to maintain the viability of organs and tissues for transplantation was described by the categories: to change paradigms, to humanize the donation process, to expand the donation, and to save lives.FINAL CONSIDERATIONS: knowledge of the experience of the nurses in this process is important for healthcare professionals who work in different realities, indicating strategies to optimize the procurement of organs and tissues for transplantation.

scholarly journals Microbial contamination and tissue procurement location: A conventional operating room is not mandatory. An observational study

PLoS ONE ◽  
2019 ◽  
Vol 14 (1) ◽  
pp. e0210140
Author(s):  
Benjamin Louart ◽  
Claire Charles ◽  
Tri-Long Nguyen ◽  
Nicolas Builles ◽  
Claire Roger ◽  
...  
Keyword(s):  
Observational Study ◽  
Operating Room ◽  
Microbial Contamination ◽  
Tissue Procurement

Bone and Soft Tissue Procurement

1989 ◽  
Vol 8 (2) ◽  
pp. 31-34 ◽  
Author(s):  
Mary L. Dekker
Keyword(s):  
Soft Tissue ◽  
Tissue Procurement

Use of resources in corneal tissue procurement

2003 ◽  
Vol 35 (3) ◽  
pp. 1002 ◽  
Author(s):  
G Bozzi ◽  
A Saviozzi ◽  
M Nardi ◽  
N Lombardi ◽  
G Giuliano
Keyword(s):  
Corneal Tissue ◽  
Use Of Resources ◽  
Tissue Procurement

Organ and tissue procurement in the acute care setting: Principles and practice — part 2

1990 ◽  
Vol 19 (2) ◽  
pp. 193-200 ◽  
Author(s):  
Emanuel P Rivers ◽  
Susan M Buse ◽  
Brack A Bivins ◽  
H Mathilda Horst
Keyword(s):  
Acute Care ◽  
Care Setting ◽  
Acute Care Setting ◽  
Tissue Procurement
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