Obtaining High-Quality Blood Specimens for Downstream Applications: A Review of Current Knowledge and Best Practices

2018 ◽  
Vol 16 (6) ◽  
pp. 411-418 ◽  
Author(s):  
Qiyuan Li ◽  
Xian Wang ◽  
Xue Li ◽  
Xuheng He ◽  
Qian Wan ◽  
...  
Keyword(s):  
Best Practices ◽  
Current Knowledge ◽  
High Quality ◽  
Blood Specimens

Critical reagent generation, characterization, handling and storage workflows: impact on ligand binding assays

Bioanalysis ◽  
2021 ◽  
Author(s):  
Elisa Oquendo ◽  
Jolaine Savoie ◽  
Joyce M Swenson ◽  
Christine Grimaldi
Keyword(s):  
Best Practices ◽  
Ligand Binding ◽  
Binding Assay ◽  
State Of The Art ◽  
Current Knowledge ◽  
Binding Assays ◽  
High Quality ◽  
The Past ◽  
Antidrug Antibodies ◽  
And Storage

The foundation of pharmacokinetics and antidrug antibodies assay robustness relies on the use of high-quality reagents. Over the past decade, there has been increasing interest within the pharmaceutical industry, as well as regulators, on defining best practices and scientific approaches for generation, characterization and handling of critical reagents. In this review, we will discuss current knowledge and practices on critical reagent workflows and state-of-the-art approaches for characterization, generation, stability and storage and how each of these steps can impact ligand-binding assay robustness.

State of the Journal, 2021

2021 ◽  
Vol 75 (6) ◽  
Author(s):  
Stacey Reynolds
Keyword(s):  
North America ◽  
Occupational Therapy ◽  
Best Practices ◽  
Manuscript Submission ◽  
High Quality ◽  
High Quality Research ◽  
Quality Research

The American Journal of Occupational Therapy (AJOT) retains its ranking as the top-rated occupational therapy journal in North America by maintaining its commitment to publishing high-quality research aimed at occupational therapy professionals. As the needs and scope of the profession continue to expand, AJOT will continue to serve as a resource to practitioners, academics, and administrators to help guide best practices. Communication and engagement with readers will be facilitated through the new AJOT website as well as the new AJOT: Authors and Issues series. The journal seeks to expand its scope through its website, manuscript submission platform, and new ways to engage readers.

scholarly journals Good practices in collecting umbilical cord and placental blood

2016 ◽  
Vol 24 (0) ◽  
Author(s):  
Lauren Auer Lopes ◽  
Elizabeth Bernardino ◽  
Karla Crozeta ◽  
Paulo Ricardo Bittencourt Guimarães
Keyword(s):  
Best Practices ◽  
Umbilical Cord ◽  
Management Tool ◽  
Blood Collection ◽  
Placental Blood ◽  
Operational Factors ◽  
Blood Specimens ◽  
Definition Of ◽  
Gathering Data

Abstract Objective: to identify the factors related to the quality of umbilical cord and placental blood specimens, and define best practices for their collection in a government bank of umbilical cord and placental blood. Method: this was a descriptive study, quantitative approach, performed at a government umbilical cord and placental blood bank, in two steps: 1) verification of the obstetric, neonatal and operational factors, using a specific tool for gathering data as non-participant observers; 2) definition of best practices by grouping non-conformities observed before, during and after blood collection. The data was analyzed using descriptive statistics and the following statistical software: Statistica(r) and R(r). Results: while there was a correlation with obstetrical and neonatal factors, there was a larger correlation with operational factors, resulting in the need to adjust the professional practices of the nursing staff and obstetrical team involved in collecting this type of blood. Based on these non-conformities we defined best practices for nurses before, during and after blood collection. Conclusion: the best practices defined in this study are an important management tool for the work of nurses in obtaining blood specimens of high cell quality.

Best Practices for Tour Guides at Christian and Islamic Religious Sites

2020 ◽  
pp. 154-180
Author(s):  
Sawsan Khreis ◽  
Jean Michel Chapuis ◽  
Mohammed Shunnaq
Keyword(s):  
Best Practices ◽  
Human Resources ◽  
Gross Domestic Product ◽  
Developing Country ◽  
Religious Activities ◽  
High Quality ◽  
Tourist Destinations ◽  
Tour Guides ◽  
Religious Tourism ◽  
High Quality Service

Tourism is a major economic pillar for many countries; it enables them to increase gross domestic product, improves the population lifestyle, and preserves natural, cultural, and religious tourism assets. Tourism appears as a magic tool that could change the future of a developing country. However, tourism requires qualified human resources who can deliver high-quality service. Tour guides assume a great responsibility as they communicate with tourists during their sojourn. Their mission is even more critical if they have to accompany tourists to sacred tourist destinations where tourists are engaged in religious activities. The best practices of guides embedded with tourist behaviors are expected to enhance a peaceful world and provide a good touristic experience.

Final Thoughts on Best Practices

2021 ◽  
pp. 95-100
Author(s):  
Amie R. Newins ◽  
Laura C. Wilson
Keyword(s):  
Sexual Assault ◽  
Best Practices ◽  
Service Delivery ◽  
High Quality ◽  
Contextual Model ◽  
Sexual Assault Survivors ◽  
Sources Of Support ◽  
Assault Survivors

Throughout the book, the authors have argued that it is important to use a contextual model to consider all of the factors that influence how survivors conceptualize what happened to them, whether or not they disclose the incident to others, and how others respond to their disclosures. It is also imperative that professionals understand how these factors may serve as barriers to survivors seeking and receiving high-quality and affirming services. In light of this, in this chapter, the authors offer more general recommendations for ways formal sources of support can improve their service delivery when working with sexual assault survivors. Overall, there have been recent gains and improvements within the disciplines that serve sexual assault survivors, as well as within society as a whole. Despite this progress, there is still more work to do.

scholarly journals Response to Letter to the Editor: COVID-19: Current Knowledge and Best Practices for Orthopaedic Surgeons

2020 ◽  
Vol 54 (6) ◽  
pp. 919-920
Author(s):  
Harvinder Singh Chhabra ◽  
Vaibhav Bagaria ◽  
Swapnil Keny ◽  
Kalyan Kumar Varma Kalidindi ◽  
Abhinandan Mallepally ◽  
...  
Keyword(s):  
Best Practices ◽  
Current Knowledge ◽  
Orthopaedic Surgeons ◽  
Letter To The Editor

scholarly journals COVID‑19: Current Knowledge and Best Practices for Orthopaedic Surgeons

2020 ◽  
Vol 54 (6) ◽  
pp. 917-918
Author(s):  
Abhishek Vaish ◽  
Vijay Kumar Jain ◽  
Karthikeyan P. Iyengar ◽  
Raju Vaishya
Keyword(s):  
Best Practices ◽  
Current Knowledge ◽  
Orthopaedic Surgeons

Screening for prostate cancer

2017 ◽  
Author(s):  
Fritz H. Schröder
Keyword(s):  
Prostate Cancer ◽  
High Risk ◽  
Early Detection ◽  
Secondary Prevention ◽  
Current Knowledge ◽  
Age Groups ◽  
Population Based ◽  
High Rate ◽  
High Quality ◽  
Prostate Cancer Mortality

Screening for a disease must be clearly defined and differentiated from early detection. ‘Screening’ refers to the application of tests to the whole population or to defined segments such as males within certain defined high risk age groups. If applied in such a fashion ‘screening’ for prostate cancer may also be described epidemiologically as ‘secondary prevention’. While high-quality randomized studies show that screening reduces prostate cancer mortality by 21–44%, there is wide agreement that the introduction of population-based screening is at present premature because harms, mainly the high rate of overdiagnosis seen currently outweighs the benefits. This chapter attempts to put current knowledge into perspective with a set of recognized prerequirements for the application of screening, established by Wilson and Jungner in 1968.

scholarly journals On “success” in applied environmental research — What is it, how can it be achieved, and how does one know when it has been achieved?

2020 ◽  
Vol 28 (4) ◽  
pp. 357-372 ◽  
Author(s):  
Steven J. Cooke ◽  
Trina Rytwinski ◽  
Jessica J. Taylor ◽  
Elizabeth A. Nyboer ◽  
Vivian M. Nguyen ◽  
...  
Keyword(s):  
Decision Making ◽  
Best Practices ◽  
Environmental Science ◽  
Early Career ◽  
Environmental Research ◽  
Relevant Research ◽  
High Quality ◽  
Partner Satisfaction ◽  
Effective Decision Making ◽  
Social Environmental

Environmental decision-makers and practitioners need and deserve high-quality environmental evidence for effective decision-making. We collate and share a suite of best practices for applied environmental researchers to support their capacity to inform such decision-making processes. This raises a number of important questions: What does “relevant” and informative evidence look like? How do we know when evidence has been applied? We assembled an experienced team of knowledge generators and users in Canada to identify insights that have emerged from their work and that could serve as guideposts for others who seek to apply environmental research to policy challenges. By reflecting on successes and failures, we define “success” in applied environmental science as respectfully conducted, partner-relevant research that is accessible, understandable, and shared and that can create opportunities for change (e.g., in policy, behaviour, management). Next, we generated a list of best practices for delivering “successful” applied environmental research. Our guidance emphasizes the importance of engaging early and often, in a respectful manner, with partners, generating high-quality, relevant research (which requires flexibility), having a plan for communicating and sharing outputs, and being transparent about uncertainties and limitations. Other important considerations include acknowledging partners for involvement and training early career researchers in applied partnership research. Finally, we generated a list of specific, measurable indicators for evaluating success, including quality and quantity of scientific outputs, the relationship with the partner(s), relevance and connectedness of the research, accessibility and availability of outputs to users, provision of outputs that are digestible and usable by different audiences, training and capacity building, and ultimate outcomes (e.g., including social, environmental, and economic outcomes, as well as partner satisfaction). We encourage those embarking on applied environmental research to consider embracing the strategies, to continuously reflect on progress toward shared research goals, and to be flexible. Doing so will increase the likelihood of delivering research that is “successful” and in doing so contribute to overcoming and addressing environmental issues and problems.

scholarly journals Audit committee compensation, best practices and audit fees

2019 ◽  
Vol 50 (1) ◽  
Author(s):  
Bum-Jin Park
Keyword(s):  
Best Practices ◽  
Financial Reporting ◽  
Regression Models ◽  
Audit Committee ◽  
Best Practice ◽  
Audit Quality ◽  
Positive Association ◽  
Audit Fees ◽  
High Quality ◽  
The Relationship

Background: It is extremely important that an audit committee (AC) monitors a company’s financial reporting process, and that the committee engages a high-quality auditor to carry this out effectively. Prior research on ACs has paid much attention to the relationship between AC best practices and audit fees (AF). Although compensation is a means of aligning interests between ACs and stakeholders, previous studies have neglected the complementary interaction between AC compensation and compliance with best practices on audit quality.Objectives: The purpose of this study is to investigate how compensation for ACs affects AF, and how the association is moderated by compliance with best practices to capture effective monitoring.Method: The regression models are estimated to verify how the relationship between AC compensation and AF is moderated by AC compliance with best practice. Moreover, the logistic regression models are used to investigate how the relationship between AC compensation and the opportunistic achievement of earnings goals is moderated by AC compliance with best practice.Results: The findings show a positive association between the levels of compensation AC members receive and AF, which is reinforced in firms that have ACs that comply with all best practices.Conclusion: The results suggest that highly paid ACs engage high-quality auditors to complement their function of monitoring management and AC compensation and compliance with best practices are complementary to enhance audit quality. This study thus provides the interesting insights that can be applicable to countries with requirements relating to the compensation schemes for ACs or the formation of the AC.

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