scholarly journals Validity of a 3-Hour Breast Milk Expression Protocol in Estimating Current Maternal Milk Production Capacity and Infant Breast Milk Intake in Exclusively Breastfeeding Dyads

2020 ◽  
Vol 15 (10) ◽  
pp. 630-638
Author(s):  
Dayna M. Roznowski ◽  
Erin A. Wagner ◽  
Sarah W. Riddle ◽  
Laurie A. Nommsen-Rivers
Keyword(s):  
Breast Milk ◽  
Milk Production ◽  
Production Capacity ◽  
Milk Intake ◽  
Maternal Milk ◽  
Breast Milk Expression

scholarly journals Domperidone and maternal milk volume in mothers of premature newborns

2017 ◽  
Vol 57 (1) ◽  
pp. 18 ◽  
Author(s):  
Tengku Ellya Fazilla ◽  
Guslihan Dasa Tjipta ◽  
Muhammad Ali ◽  
Pertin Sianturi
Keyword(s):  
Placebo Group ◽  
Breast Milk ◽  
Milk Production ◽  
Controlled Trial ◽  
Maternal Milk ◽  
Premature Newborns ◽  
Breast Milk Production ◽  
Days Of Therapy ◽  
Significant Difference ◽  
Milk Volume

Background Mothers of premature newborns often have difficulty giving adequate breast milk volume to their infants. Domperidone is an antagonist of peripheral dopamine receptors and believed to increase breast milk production. In Indonesia, no study has been done to date on the effect of domperidone on maternal milk production in mothers of premature newborns.  Objective To evaluate the effect of domperidone on milk production in mothers of premature newborns who failed to lactate.Methods A randomized controlled trial was conducted from July to December 2012 in the Perinatology Unit, Haji Adam Malik Hospital, Medan. Mothers of premature newborns were given lactation counseling for 7 days in order to increase their milk production. Mothers who failed to lactate after that time were enrolled in the study. Fifty subjects were assigned to receive either domperidone or a placebo for 7 days. Milk volume was measured every 2 hours (from 7 am to 9 pm), in the 24 hours before starting therapy, and on the 7th and 10th days (the 10th day being 3 days after stopping therapy). Results This study involved 25 mothers in the domperidone groups and 25 others in placebo group. After 7 days of therapy, mean breast milk volume was significantly higher in the domperidone group than in the placebo group  [181.6 (SD 80.2) vs. 72.4 (SD 57.8) mL, respectively; 95%CI of differences 69.36 to 148.93; P=0.0001]. At day 10, breast milk production remained significantly higher in the domperidone group. Furthermore, in the domperidone group, no significant difference in mean breast milk volumes was noted between the 7th and 10th days (P=0.65). Conclusion In mothers of premature newborns who failed to lactate, domperidone therapy for 7 days causes significantly higher milk production compared to placebo. 

scholarly journals Comparison of Infant Test-Weighing and Hourly Breast Expression in Measuring Maternal Milk Production (P11-041-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Dayna Roznowski ◽  
Erin Wagner ◽  
Sarah Riddle ◽  
Laurie Nommsen-Rivers
Keyword(s):  
Steady State ◽  
Production Rate ◽  
Milk Production ◽  
Production Capacity ◽  
Limits Of Agreement ◽  
Term Infants ◽  
Maternal Milk ◽  
Milk Output ◽  
Before And After ◽  
The Difference

Abstract Objectives Measuring maternal milk production is cumbersome. Our objectives were to: 1) confirm that milk production rate reaches steady state at hour 2 of hourly breast emptying; and 2) compare agreement in milk production when measured using the well-established test-weighing method versus the more efficient hourly breast emptying method (Lai, et al., Breastfeeding Medicine, 2010). Methods Eligible mothers were 4–10 weeks postpartum and exclusively breastfeeding their healthy, singleton, term infants. A subset of mothers test-weighed (TW) their infant (± 2 g) before and after breastfeeding for 48h. Within 1 week of TW, mothers had a morning visit at the research clinic for hourly breast expression measurements. Mothers emptied both breasts at baseline (h0), and 1, 2, and 3 hours after baseline (h1, h2, h3) using a hospital-grade pump. We recorded hourly milk output ± 1 g and adjusted production rate (g/h) to exact interval (minutes from end of previous to end of current expression). We used paired t-test to compare g/h at h3 versus h0, h1, and h2. We estimated mother's steady-state milk production rate (MPR, g/h) as mean (h2, h3). We used the Bland-Altman method for determining the 95% limits of agreement in measuring milk production (g/24h) using TW versus MPRx24. Results 23 mothers (65% primiparous) were 54 ± 14 days postpartum. Milk output was 185 ± 55 g at h0 and 60 ± 26, 47 ± 13, 44 ± 13 g/h at h1, h2, and h3, respectively. Mean paired difference (vs. h3) was significant at h0 and h1 (P < 0.05), but not at h2 (P > 0.05, h3 - h2 = 3 ± 10 g/h). In the subset with TW data (n = 16), mean TW milk output was 717 ± 119 g/24h, and mean MPRx24 was 1085 ± 300 g/24h. Mean difference, MPRx24 - TW [± 95% limits of agreement], was 368 [± 468] g/24h; and mean ratio, MPRx24/TW, was 1.5 [± 0.4]. Both difference and ratio significantly increased as MPR increased (P < 0.05). Conclusions Hourly milk production reaches steady state at h2; thus, mean (h2, h3) is a valid measure of current maternal milk production capacity. However, there was not homogeneous agreement between MPR and TW, and the 95% limits of agreement were very wide: -91 to 459 g/24h when expressed as the difference, and 0.9 to 1.9-fold as a ratio. Thus, MPR is feasible for researching variation in maternal milk production but not for researching variation in infant intake. Funding Sources None. Supporting Tables, Images and/or Graphs

Formula Supplementation of the Breastfed Infant: Assault on the Gut Microbiome

2014 ◽  
Vol 5 (4) ◽  
pp. 128-132 ◽  
Author(s):  
Marsha Walker
Keyword(s):  
Breast Milk ◽  
Health Outcomes ◽  
Milk Production ◽  
Gut Microbiome ◽  
Side Effect ◽  
Early Life ◽  
Microbial Colonization ◽  
Mucosal Inflammation ◽  
Maternal Milk ◽  
Allergic Disorders

Although formula supplementation is well known to have detrimental effects on the duration and exclusivity of breastfeeding, on the maternal milk production, and on the health outcomes of mothers and infants, there are immediate and long-lasting effects on the infant’s gut microbiome. Breast milk is an important element modulating the metabolic and immunological programming relative to a child’s health. An unfavorable or abnormal microbial colonization during early life interferes with many functions in the gut and facilitates invasion of pathogens and foreign or harmful antigens. Alterations of the gut environment (such as from supplementation with formula) are directly responsible for mucosal inflammation and disease, autoimmunity conditions, and allergic disorders in childhood and adulthood. Clinicians and parents will benefit from knowledge of this side effect of formula supplementation.

scholarly journals Safety and Efficacy of Galactogogues: Substances that Induce, Maintain and Increase Breast Milk Production

2010 ◽  
Vol 13 (2) ◽  
pp. 162 ◽  
Author(s):  
Antonio Alberto Zuppa ◽  
Paola Sindico ◽  
Claudia Orchi ◽  
Chiara Carducci ◽  
Valentina Cardiello ◽  
...  
Keyword(s):  
Growth Hormone ◽  
Breast Milk ◽  
Milk Production ◽  
Milk Thistle ◽  
Thyrotrophin Releasing Hormone ◽  
Maternal Milk ◽  
Safety And Efficacy ◽  
Natural Substances ◽  
Breast Milk Production ◽  
Other Substances

Poor production of breast milk is the most frequent cause of breast lactation failure. Often, physician prescribe medications or other substances to solve this problem. The use of galactogogues should be limited to those situations in which reduced milk production from treatable causes has been excluded. One of the most frequent indication for the use of galactogogues is the diminution of milk production in mothers using indirect lactation, particularly in the case of preterm birth. The objective of this review is to analyze to the literature relating to the principal drugs used as galactogogues (metoclopramide, domperidone, chlorpromazine, sulpiride, oxytocin, growth hormone, thyrotrophin releasing hormone, medroxyprogesterone). Have been also analyzed galactogogues based on herbs and other natural substances (fenugreek, galega and milk thistle). We have evaluated their mechanism of action, transfer to maternal milk, effectiveness and potential side effects for mother and infant, suggested doses for galactogogic effect, and recommendation for breastfeeding.

Services Provided for Lactating Mothers at Lactation Management Clinic in Selected Tertiary Level Hospitals

2020 ◽  
Vol 38 (2) ◽  
pp. 68-73
Author(s):  
Tarannum Tasnim ◽  
ANM Shamsul Islam ◽  
Mehedi Hasan Azad ◽  
Farhana Sharmin
Keyword(s):  
Breast Milk ◽  
Milk Production ◽  
Public Awareness ◽  
Cross Sectional Study ◽  
Dietary Advice ◽  
Tertiary Level ◽  
Cross Sectional ◽  
Breast Milk Production ◽  
Lactating Mothers ◽  
Structured Questionnaire

Background: Children are the precious gift from the Almightily Allah and breast milk is an ideal product given to the human being by nature to fulfill all requirements of the offspring until they are matured enough to take adult food. Objective: To assess the services provided for lactating mothers at lactation management centre in selected tertiary level hospitals. Materials and Methods: This cross sectional study was conducted among 100 Lactating mothers who were selected conveniently and were interviewed by pre-tested semi-structured questionnaire and an observational checklist. Collected data were processed and analyzed using SPSS (Statistical Packages for Social Science) software. Results: Lactation management centre (LMC) is supervised by a consultant and separate room is allotted in both out-patient and in-patient departments. Mothers came with lactation problems were more likely in the first month of the baby (73%) and feeling of not enough milk production was common (49%).Highly significant relationship was found between breast problems of lactating mother and age of child (p<0.001). About 84% respondents received practical demonstration on position and attachment of the baby during lactation. About 91% respondents got dietary advice for enough breast milk production, 75% got dietary advice regarding their child’s weaning food chart and69% got health education. Maximum mothers were informed about LMC by doctor & nurse (82%). Conclusion: Information about LMC services should be disseminated across the country. Lactating mothers should be familiarized with LMC and public awareness should be enhanced for effective management of breastfeeding problem to promote, protect and support the breastfeeding. JOPSOM 2019; 38(2): 68-73

Penatalaksanaan IMD pada Ibu Postpartum Sectio Caesarea Mempengaruhi Status Gizi dan Kecepatan Produksi ASI

2020 ◽  
Vol 2 (2) ◽  
pp. 112-120
Author(s):  
Nursari Abdul Syukur ◽  
Susi Purwanti
Keyword(s):  
Breast Milk ◽  
Nutritional Status ◽  
Milk Production ◽  
Quantitative Research ◽  
Milk Protein ◽  
Sectio Caesarea ◽  
Control Group ◽  
P Value ◽  
Study Results

Many mothers who give birth to Sectio Caesarea (SC) do not Initiate Early Breastfeeding (IMD), which fails exclusive breastfeeding. This study aimed to determine the effect of IMD management in postpartum SC mothers on nutritional status, speed of milk production, and quality of breast milk protein. Method: quantitative research with quasi approach experiment. The research design used was a pre-post-test control non-equivalent control group. A sampling of this study used the Consecutive method sampling with a sample of 20 mothers who gave birth by cesarean section (SC). Hypothesis testing uses the independent t-test and the Mann-Whitney test. The study results showed an influence on the management of IMD in postpartum SC mothers on the speed of ASI production (p-value=0.004) and nutritional status (p-value=0.028). There was no effect of IMD management on postpartum SC mothers on the quality of breast milk protein (p-value = 0.543). This study recommends that the hospital implement an IMD promotion program before the abdominal wall is closed as a form of intervention to increase milk production and maternal nutritional status

Prevalence of Breast Milk Expression and Associated Factors

PEDIATRICS ◽  
2008 ◽  
Vol 122 (Supplement 2) ◽  
pp. S63-S68 ◽  
Author(s):  
Judith Labiner-Wolfe ◽  
Sara B. Fein ◽  
Katherine R. Shealy ◽  
Cunlin Wang
Keyword(s):  
Breast Milk ◽  
Associated Factors ◽  
Breast Milk Expression
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